Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Stéphane, Lolignier"'
Autor:
Maëva Meynier, Valentine Daugey, Geoffroy Mallaret, Sandie Gervason, Mathieu Meleine, Julie Barbier, Youssef Aissouni, Stéphane Lolignier, Mathilde Bonnet, Denis Ardid, Willem M. De Vos, Matthias Van Hul, Peter Suenaert, Amandine Brochot, Patrice D. Cani, Frédéric A. Carvalho
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
ABSTRACTGut – brain communications disorders in irritable bowel syndrome (IBS) are associated with intestinal microbiota composition, increased gut permeability, and psychosocial disturbances. Symptoms of IBS are difficult to medicate, and hence mu
Externí odkaz:
https://doaj.org/article/cb9803d64116443f855c9388193c7f9a
Autor:
Mélissa Delanne-Cuménal, Sylvain Lamoine, Mathieu Meleine, Youssef Aissouni, Laetitia Prival, Mathilde Fereyrolles, Julie Barbier, Christine Cercy, Ludivine Boudieu, Julien Schopp, Michel Lazdunski, Alain Eschalier, Stéphane Lolignier, Jérôme Busserolles
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 176, Iss , Pp 116887- (2024)
Background: The metastasis of tumors into bone tissue typically leads to intractable pain that is both very disabling and particularly difficult to manage. We investigated here whether riluzole could have beneficial effects for the treatment of prost
Externí odkaz:
https://doaj.org/article/fba694993c0445fda652c636373e8655
Autor:
Stéphane Lolignier, Caroline Bonnet, Christelle Gaudioso, Jacques Noël, Jérôme Ruel, Muriel Amsalem, Jérémy Ferrier, Lise Rodat-Despoix, Valentine Bouvier, Youssef Aissouni, Laetitia Prival, Eric Chapuy, Françoise Padilla, Alain Eschalier, Patrick Delmas, Jérôme Busserolles
Publikováno v:
Cell Reports, Vol 11, Iss 7, Pp 1067-1078 (2015)
Cold-triggered pain is essential to avoid prolonged exposure to harmfully low temperatures. However, the molecular basis of noxious cold sensing in mammals is still not completely understood. Here, we show that the voltage-gated Nav1.9 sodium channel
Externí odkaz:
https://doaj.org/article/b41660b502d941c294543319bb5331b1
Autor:
Laetitia Prival, Emmanuel Bourinet, Jérôme Busserolles, Vanessa Pereira, David Balayssac, Sylvain Lamoine, Alain Eschalier, Anne Pizzoccaro, Mélissa Cuménal, Stéphane Lolignier, Youssef Aissouni
Publikováno v:
Molecular Neurobiology
Molecular Neurobiology, Humana Press, 2021, 58 (7), pp.3575-3587. ⟨10.1007/s12035-021-02361-6⟩
Molecular Neurobiology, 2021, 58 (7), pp.3575-3587. ⟨10.1007/s12035-021-02361-6⟩
Molecular Neurobiology, Humana Press, 2021, 58 (7), pp.3575-3587. ⟨10.1007/s12035-021-02361-6⟩
Molecular Neurobiology, 2021, 58 (7), pp.3575-3587. ⟨10.1007/s12035-021-02361-6⟩
International audience; Peripheral neuropathy is the most frequent dose-limiting adverse effect of oxaliplatin. Acute pain symptoms that are induced or exacerbated by cold occur in almost all patients immediately following the first infusions. Eviden
Autor:
Maïly Devilliers, Eric Chapuy, Florian Lesage, Florence Noble, Julien Schopp, Alain Eschalier, Jérôme Busserolles, Laura Poupon, Loïc Clémenceau, Laetitia Pouchol, Serge Richard, Mathieu Meleine, Sylvie Ducki, Celine Judon, Nicolas Marie, Ismail Ben Soussia, Stéphane Lolignier
Publikováno v:
British Journal of Pharmacology
British Journal of Pharmacology, 2020, 177 (20), pp.4782-4795. ⟨10.1111/bph.15243⟩
British Journal of Pharmacology, Wiley, 2020, 177 (20), pp.4782-4795. ⟨10.1111/bph.15243⟩
Br J Pharmacol
British Journal of Pharmacology, 2020, 177 (20), pp.4782-4795. ⟨10.1111/bph.15243⟩
British Journal of Pharmacology, Wiley, 2020, 177 (20), pp.4782-4795. ⟨10.1111/bph.15243⟩
Br J Pharmacol
International audience; Background and Purpose: Opioids are effective painkillers. However, their risk-benefit ratio is dampened by numerous adverse effects and opioid misuse has led to a public health crisis. Safer alternatives are required, but iso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f70c964ceae3c40fc977b9b77e572245
https://uca.hal.science/hal-03512213/document
https://uca.hal.science/hal-03512213/document
Autor:
Dimitra, Gkika, Stéphane, Lolignier, Guillaume P, Grolez, Alexis, Bavencoffe, Georges, Shapovalov, Dmitri, Gordienko, Artem, Kondratskyi, Mathieu, Meleine, Laetitia, Prival, Eric, Chapuy, Monique, Etienne, Alain, Eschalier, Yaroslav, Shuba, Roman, Skryma, Jérôme, Busserolles, Natalia, Prevarskaya
Publikováno v:
FASEB Journal
FASEB Journal, Federation of American Society of Experimental Biology, 2020, 34 (6), pp.7483-7499. ⟨10.1096/fj.201902270R⟩
FASEB Journal, 2020, 34 (6), pp.7483-7499. ⟨10.1096/fj.201902270R⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2020, 34 (6), pp.7483-7499. ⟨10.1096/fj.201902270R⟩
FASEB Journal, 2020, 34 (6), pp.7483-7499. ⟨10.1096/fj.201902270R⟩
International audience; Recent studies have revealed gender differences in cold perception, and pointed to a possible direct action of testosterone (TST) on the cold-activated TRPM8 (Transient Receptor Potential Melastatin Member 8) channel. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a3720930f75b7ae7d1f35c0cb881acbc
https://hal.uca.fr/hal-03512394
https://hal.uca.fr/hal-03512394
Autor:
Stéphane Lolignier, Muriel Amsalem, François Maingret, Françoise Padilla, Mélanie Gabriac, Eric Chapuy, Alain Eschalier, Patrick Delmas, Jérôme Busserolles
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23083 (2011)
Inflammation is known to be responsible for the sensitization of peripheral sensory neurons, leading to spontaneous pain and invalidating pain hypersensitivity. Given its role in regulating neuronal excitability, the voltage-gated Nav1.9 channel is a
Externí odkaz:
https://doaj.org/article/fdd502ad8c7744639fcd1d797028d43d
Autor:
Nicolas Authier, Alain Eschalier, Célian Bertin, Jérôme Busserolles, Stéphane Lolignier, Nicolas Kerckhove
Publikováno v:
Pharmacology and Therapeutics
Pharmacology and Therapeutics, 2020, 210, pp.107519-. ⟨10.1016/j.pharmthera.2020.107519⟩
Pharmacology and Therapeutics, Elsevier, 2020, 210, pp.107519-. ⟨10.1016/j.pharmthera.2020.107519⟩
Pharmacology and Therapeutics, 2020, 210, pp.107519-. ⟨10.1016/j.pharmthera.2020.107519⟩
Pharmacology and Therapeutics, Elsevier, 2020, 210, pp.107519-. ⟨10.1016/j.pharmthera.2020.107519⟩
The scarcity and limited risk/benefit ratio of painkillers available on the market, in addition to the opioid crisis, warrant reflection on new innovation strategies. The pharmacopoeia of analgesics is based on products that are often old and derived
Autor:
Jérôme Busserolles, Laura Poupon, Youssef Aissouni, Stéphane Lolignier, Nicolas Authier, David Balayssac, Nicolas Kerckhove, David André Barrière, Fabrice Giraudet, Damien Richard, Michel Lazdunski, Alain Eschalier, Mathieu Meleine, Sylvain Lamoine, Vanessa Pereira, Laetitia Prival
Publikováno v:
Neuropharmacology
Neuropharmacology, Elsevier, 2018, 140, pp.43-61. ⟨10.1016/j.neuropharm.2018.07.026⟩
Neuropharmacology, 2018, 140, pp.43-61. ⟨10.1016/j.neuropharm.2018.07.026⟩
Neuropharmacology, Elsevier, 2018, 140, pp.43-61. ⟨10.1016/j.neuropharm.2018.07.026⟩
Neuropharmacology, 2018, 140, pp.43-61. ⟨10.1016/j.neuropharm.2018.07.026⟩
International audience; Neurotoxicity remains the most common adverse effect of oxaliplatin, limiting its clinical use. In the present study, we developed a mouse model of chronic oxaliplatin-induced neuropathy, which mimics both sensory and motor de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8180b728beaf66f765518896817c4cd0
https://hal.archives-ouvertes.fr/hal-02065469
https://hal.archives-ouvertes.fr/hal-02065469
Autor:
Queensta Millet, Jane E. Sexton, Julie Tordo, Alice M. Fuller, Michael Linden, Stephen E. Moss, Jyoti S. Choudhary, Els Henckaerts, Stéphane Lolignier, Vanessa Pereira, Richard J. Lewis, Sonia Santana-Varela, John N. Wood, Ramin Raouf, Anna M Biller, Mark O. Collins
Publikováno v:
Science Signaling
Science Signaling, American Association for the Advancement of Science, 2018, 11 (535), ⟨10.1126/scisignal.aao2060⟩
Science Signaling, American Association for the Advancement of Science (AAAS), 2018, 11 (535), ⟨10.1126/scisignal.aao2060⟩
Raouf, R, Lolignier, S, Sexton, J E, Millet, Q, Santana-Varela, S, Biller, A, Fuller, A M, Pereira, V, Choudhary, J S, Collins, M O, Moss, S E, Lewis, R, Tordo, J, Henckaerts, E, Linden, M & Wood, J N 2018, ' Inhibition of somatosensory mechanotransduction by annexin A6 ', Science Signaling, vol. 11, no. 535, eaao2060 . https://doi.org/10.1126/scisignal.aao2060
Science Signaling, American Association for the Advancement of Science, 2018, 11 (535), ⟨10.1126/scisignal.aao2060⟩
Science Signaling, American Association for the Advancement of Science (AAAS), 2018, 11 (535), ⟨10.1126/scisignal.aao2060⟩
Raouf, R, Lolignier, S, Sexton, J E, Millet, Q, Santana-Varela, S, Biller, A, Fuller, A M, Pereira, V, Choudhary, J S, Collins, M O, Moss, S E, Lewis, R, Tordo, J, Henckaerts, E, Linden, M & Wood, J N 2018, ' Inhibition of somatosensory mechanotransduction by annexin A6 ', Science Signaling, vol. 11, no. 535, eaao2060 . https://doi.org/10.1126/scisignal.aao2060
Patients with osteoarthritis experience pain when moving or, sometimes, touching the affected joints. Raouf et al. identified proteins that bound to a toxin that inhibits mechanically induced pain, including the membrane-binding protein annexin A6. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::817616de32e174a126da9c7636d79807
https://hal.uca.fr/hal-03512530
https://hal.uca.fr/hal-03512530