Acceptability of oral liquid pharmaceutical products in older adults: palatability and swallowability issues

Autor: Emilie Belissa, Thibault Vallet, Sandra Laribe-Caget, Alain Chevallier, François-Xavier Chedhomme, Fattima Abdallah, Nathalie Bachalat, Sid-Ahmed Belbachir, Imad Boulaich, Vanessa Bloch, Anne Delahaye, Mathieu Depoisson, Amélie Dufaÿ Wojcicki, Stéphane Gibaud, Anne-Sophie Grancher, Caroline Guinot, Celia Lachuer, Laurent Lechowski, Patrick Leglise, Abdel Mahiou, Sylvie Meaume, Corinne Michel, Hugues Michelon, Yann Orven, Ines Perquy, Matthieu Piccoli, Maïté Rabus, Annie-Claude Ribemont, Jean-Paul Rwabihama, Jean-Hugues Trouvin, Fabrice Ruiz, Vincent Boudy

Publikováno v: BMC Geriatrics, Vol 19, Iss 1, Pp 1-9 (2019)

Abstract Background In institutional care, oral liquid pharmaceutical products are widely prescribed for older patients, especially for those with swallowing disorders. As medicines acceptability is a key factor for compliance in the older population

Externí odkaz: https://doaj.org/article/3ed861da67864ca7a527076ccf2f066b

Anticancer properties of lipid and poly(ε-caprolactone) nanocapsules loaded with ferrocenyl-tamoxifen derivatives

Autor: Lucie Sancey, Benoit Busser, Mylène Pezet, Stéphane Gibaud, Ali Rhouma, Gérard Jaouen, Pascal Pigeon, Naziha Marrakchi, Sonia Aroui, Feten Najlaoui, Michel De Waard

Publikováno v: Journal of Pharmacy and Pharmacology
Journal of Pharmacy and Pharmacology, Royal Pharmaceutical Society of Great Britain, 2018, 70 (11), pp.1474-1484. ⟨10.1111/jphp.12998⟩

Objective We synthesized new tamoxifen derivatives as anticancer drug candidates and elaborated on convection-enhanced delivery (CED) as a strategy for delivery. Methods To overcome the issue of their poor solubility, these ferrocenyl-tamoxifen deriv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49bb72fa54a81d60ecc3c72b49cf7c75
https://doi.org/10.1111/jphp.12998

Acceptability of oral liquid pharmaceutical products in older adults: palatability and swallowability issues

Autor: Hugues Michelon, François-Xavier Chedhomme, Jean-Paul Rwabihama, Caroline Guinot, Matthieu Piccoli, Vanessa Bloch, Corinne Michel, Ines Perquy, Sylvie Meaume, Amélie Dufaÿ Wojcicki, Nathalie Bachalat, Mathieu Depoisson, Sandra Laribe-Caget, Emilie Belissa, Imad Boulaich, Patrick Leglise, Anne-Sophie Grancher, Vincent Boudy, Anne Delahaye, Abdel Mahiou, Alain Chevallier, Laurent Lechowski, Maite Rabus, Fattima Abdallah, Thibault Vallet, Jean-Hugues Trouvin, Fabrice Ruiz, Stéphane Gibaud, Annie-Claude Ribemont, Celia Lachuer, Sid-Ahmed Belbachir, Yann Orven

Publikováno v: BMC Geriatrics
BMC Geriatrics, Vol 19, Iss 1, Pp 1-9 (2019)
BMC Geriatrics, BioMed Central, 2019, 19 (1), pp.344. ⟨10.1186/s12877-019-1337-2⟩

Background In institutional care, oral liquid pharmaceutical products are widely prescribed for older patients, especially for those with swallowing disorders. As medicines acceptability is a key factor for compliance in the older population, this st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a37d27ec237a452b1ae8713efa2b01c0
http://europepmc.org/articles/PMC6898963

A Decision Support Tool Facilitating Medicine Design for Optimal Acceptability in The Older Population

Autor: Anne Delahaye, Stéphane Gibaud, Anne-Sophie Grancher, Vincent Boudy, Sandra Laribe-Caget, Corinne Michel, Alain Chevallier, Sylvie Meaume, Matthieu Piccoli, Vanessa Bloch, François-Xavier Chedhomme, Thibault Vallet, Amélie Dufaÿ-Wojcicki, Annie-Claude Ribemont, Fattima Abdallah, Imad Boulaich, Maite Rabus, Patrick Leglise, Laurent Lechowski, Ines Perquy, Abdel Mahiou, Fabrice Ruiz, Emilie Belissa, Yann Orven, Nathalie Bachalat, Mathieu Depoisson, Sid-Ahmed Belbachir, Caroline Guinot, Celia Lachuer, Hugues Michelon, Jean-Paul Rwabihama, Jean-Hugues Trouvin

Publikováno v: Pharmaceutical Research
Pharmaceutical Research, American Association of Pharmaceutical Scientists, 2018, 35 (7), pp.136. ⟨10.1007/s11095-018-2424-3⟩
Pharmaceutical Research, 2018, 35 (7), pp.136. ⟨10.1007/s11095-018-2424-3⟩

International audience; PurposeMedicine acceptability, which is of the utmost importance for vulnerable patients’ adherence, is driven by both user and product characteristics. Herein, a novel multivariate approach integrating the many aspects of a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c52f410bbb515cf912b12395dca5fd7
https://hal.archives-ouvertes.fr/hal-01793642/document

Spray-dried microparticles of glutathione and S-nitrosoglutathione based on Eudragit® FS 30D polymer

Autor: Marie Socha, Stéphane Gibaud, Shefaat Ullah Shah, C. Sejil

Publikováno v: Annales Pharmaceutiques Françaises
Annales Pharmaceutiques Françaises, Elsevier Masson, 2017, 75 (2), pp.95-104. ⟨10.1016/j.pharma.2016.09.001⟩

Summary Objective In recent years, S-nitrosoglutathione has been proposed for the treatment of Crohn's disease to prevent mucosal barrier failure. In this paper, we report the formulation of spray dried microparticles of glutathione and S-nitrosoglut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::799acc75a61bce8647109d66b6e16f54
https://hal.univ-lorraine.fr/hal-01875168