Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Stéphane, Brézillon"'
Autor:
Charlie Colin-Pierre, Oussama El Baraka, Louis Danoux, Vincent Bardey, Valérie André, Laurent Ramont, Stéphane Brézillon
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-17 (2022)
Abstract Heparan sulfate proteoglycans (HSPGs) are part of proteoglycan family. They are composed of heparan sulfate (HS)-type glycosaminoglycan (GAG) chains covalently linked to a core protein. By interacting with growth factors and/or receptors, th
Externí odkaz:
https://doaj.org/article/af0205d265134fe5af6b980d6f49e4f6
Autor:
Charlie Colin-Pierre, Nicolas Berthélémy, Nicolas Belloy, Louis Danoux, Vincent Bardey, Romain Rivet, Solène Mine, Christine Jeanmaire, François-Xavier Maquart, Laurent Ramont, Stéphane Brézillon
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The hair renewal involves changes in the morphology of the hair follicle and its micro-vascularization. In alopecia, the hair cycle is accelerated, resulting in the formation of thinner and shorter hair. In addition, alopecia is associated with a dec
Externí odkaz:
https://doaj.org/article/7eb3a986ed1147df8fa7646514434c09
Autor:
Stéphane Brézillon, Valérie Untereiner, Hossam Taha Mohamed, Estelle Ahallal, Isabelle Proult, Pierre Nizet, Camille Boulagnon-Rombi, Ganesh. D. Sockalingum
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Melanoma is the most aggressive type of cutaneous malignancies. In addition to its role as a regulator of extracellular matrix (ECM) integrity, lumican, a small leucine-rich proteoglycan, also exhibits anti-tumor properties in melanoma. This work foc
Externí odkaz:
https://doaj.org/article/55733cfea8714dabb7280ab4b20104c0
Autor:
Lise Nannan, Valérie Untereiner, Isabelle Proult, Camille Boulagnon-Rombi, Charlie Colin-Pierre, Ganesh D. Sockalingum, Stéphane Brézillon
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Proteoglycans (PG) play an important role in maintaining the extracellular matrix (ECM) integrity. Lumican, a small leucine rich PG, is one such actor capable of regulating such properties. In this study, the integrity of the dermis of lumican-delete
Externí odkaz:
https://doaj.org/article/705a3fe75921405c901d753f161d554a
Autor:
Sylvie Brassart-Pasco, Stéphane Brézillon, Bertrand Brassart, Laurent Ramont, Jean-Baptiste Oudart, Jean Claude Monboisse
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
The tumor microenvironment (TME) is composed of various cell types embedded in an altered extracellular matrix (ECM). ECM not only serves as a support for tumor cell but also regulates cell–cell or cell–matrix cross-talks. Alterations in ECM may
Externí odkaz:
https://doaj.org/article/a8c221074db041958df9a85265512ff6
Autor:
Albin Jeanne, Valérie Untereiner, Corinne Perreau, Isabelle Proult, Cyril Gobinet, Camille Boulagnon-Rombi, Christine Terryn, Laurent Martiny, Stéphane Brézillon, Stéphane Dedieu
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Abstract Lumican is a small leucine-rich proteoglycan (SLRP) being known as a key regulator of collagen fibrillogenesis. However, little attention has been given so far in studying its influence on tumor-associated matrix architecture. Here, we inves
Externí odkaz:
https://doaj.org/article/c046d2d73c534d8cab21461a5d461157
Autor:
Konstantina Karamanou, Marco Franchi, Isabelle Proult, Romain Rivet, Demitrios Vynios, Stéphane Brézillon
Publikováno v:
Cells, Vol 10, Iss 4, p 841 (2021)
It was reported that lumican inhibits the activity of metalloproteinase MMP-14 and melanoma cell migration in vitro and in vivo. Moreover, Snail triggers epithelial-to-mesenchymal transition and the metastatic potential of cancer cells. Therefore, th
Externí odkaz:
https://doaj.org/article/a035e290620a41b0bd220940f49557ab
Autor:
Charlie Colin-Pierre, Valérie Untereiner, Ganesh D. Sockalingum, Nicolas Berthélémy, Louis Danoux, Vincent Bardey, Solène Mine, Christine Jeanmaire, Laurent Ramont, Stéphane Brézillon
Publikováno v:
Biomolecules, Vol 11, Iss 2, p 192 (2021)
The expression of glypicans in different hair follicle (HF) compartments and their potential roles during hair shaft growth are still poorly understood. Heparan sulfate proteoglycan (HSPG) distribution in HFs is classically investigated by convention
Externí odkaz:
https://doaj.org/article/b974d153f5834b3e858ac3db78664e44
Publikováno v:
Journal of Visualized Experiments.
Autor:
Romain Rivet, Rajas Mallenahalli Rao, Pierre Nizet, Nicolas Belloy, Louise Huber, Manuel Dauchez, Laurent Ramont, Stéphanie Baud, Stéphane Brézillon
Publikováno v:
American journal of physiology. Cell physiology.
Small leucine-rich proteoglycans (SLRPs) are major regulators of extracellular matrix assembly and cell signaling. Lumican, a member of the SLRPs family, and its derived peptides were shown to possess antitumor activity by interacting directly with t