Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Stéphane Huet"'
Autor:
James Michael Woolven, Eugene T. Grygielko, Françoise Gellibert, Neil Mathews, Stéphane Huet, Nicholas J. Laping, Angela Patikis, Cécile Bertho-Ruault, Anne-Charlotte de Gouville, Van-Loc Nguyen
Publikováno v:
Journal of Medicinal Chemistry. 49:2210-2221
Inhibitors of transforming growth factor beta (TGF-beta) type I receptor (ALK5) offer a novel approach for the treatment of fibrotic diseases such as renal, hepatic, and pulmonary fibrosis. The optimization of a novel phenylpyridine pyrazole series (