Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ssu-Ting Lien"'
Autor:
Sing-Han Huang, Yi-Ting Chen, Xiang-Yu Lin, Yi-Yi Ly, Ssu-Ting Lien, Pei-Hsin Chen, Cheng-Tang Wang, Suh-Chin Wu, Chwen-Cheng Chen, Ching-Yung Lin
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The COVID-19 pandemic has had a widespread impact on a global scale, and the evolution of considerable dominants has already taken place. Some variants contained certain key mutations located on the receptor binding domain (RBD) of spike pro
Externí odkaz:
https://doaj.org/article/cb0c8d13813245d7a48bd64f32a5581e
Autor:
Chao-Di Chang, Min-Wu Chao, Hsueh-Yun Lee, Yi-Ting Liu, Huang-Ju Tu, Ssu-Ting Lien, Tony Eight Lin, Tzu-Ying Sung, Shih-Chung Yen, Sing-Han Huang, Kai-Cheng Hsu, Shiow-Lin Pan
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
Inhibiting a specific target in cancer cells and reducing unwanted side effects has become a promising strategy in pancreatic cancer treatment. MAP4K4 is associated with pancreatic cancer development and correlates with poor clinical outcomes. By pho
Externí odkaz:
https://doaj.org/article/eeb87040e05f48b3ad27fb6a79897905
Autor:
Kuan-Chih Wang, Mei-Chin Lu, Kai-Cheng Hsu, Mohamed El-Shazly, Shou-Ping Shih, Ssu-Ting Lien, Fu-Wen Kuo, Shyh-Chyun Yang, Chun-Lin Chen, Yu-Chen S. H. Yang
Publikováno v:
Molecules, Vol 26, Iss 22, p 7037 (2021)
Xestoquinone is a polycyclic quinone-type metabolite with a reported antitumor effect. We tested the cytotoxic activity of xestoquinone on a series of hematological cancer cell lines. The antileukemic effect of xestoquinone was evaluated in vitro and
Externí odkaz:
https://doaj.org/article/0f779598f48a428d996bf6389ff62567
Publikováno v:
Computers in Biology and Medicine. 156:106722
Autor:
Tzu Ying Sung, Liang Chieh Chen, Ssu Ting Lien, Yi Wen Wu, Sin Ting Ngo, Shiow Lin Pan, Shih Chung Yen, Hui Ju Tseng, Kai Cheng Hsu, Tony Eight Lin, Han Li Huang, Wei Jan Huang
Publikováno v:
Journal of Natural Products. 84:1-10
Acute myeloid leukemia (AML) is an aggressive disease with a poor prognosis and a high degree of relapse seen in patients. Overexpression of FMS-like tyrosine kinase 3 (FLT3) is associated with up to 70% of AML patients. Wild-type FLT3 induces prolif
Autor:
Shyh-Chyun Yang, Fu-Wen Kuo, Mei-Chin Lu, Yu-Chen S. H. Yang, Kuan-Chih Wang, Shou-Ping Shih, Chun-Lin Chen, Ssu-Ting Lien, Kai-Cheng Hsu, Mohamed El-Shazly
Publikováno v:
Molecules, Vol 26, Iss 7037, p 7037 (2021)
Molecules; Volume 26; Issue 22; Pages: 7037
Molecules
Molecules; Volume 26; Issue 22; Pages: 7037
Molecules
Xestoquinone is a polycyclic quinone-type metabolite with a reported antitumor effect. We tested the cytotoxic activity of xestoquinone on a series of hematological cancer cell lines. The antileukemic effect of xestoquinone was evaluated in vitro and
Autor:
Shih-Chung Yen, Liang-Chieh Chen, Han-Li Huang, Wei-Chun HuangFu, Yi-Ying Chen, Tony Eight Lin, Ssu-Ting Lien, Hui-Ju Tseng, Tzu-Ying Sung, Jui-Hua Hsieh, Wei-Jan Huang, Shiow-Lin Pan, Kai-Cheng Hsu
Publikováno v:
Bioorganic chemistry. 121
Fms-like tyrosine kinase 3 (FLT3) is considered a promising therapeutic target for acute myeloid leukemia (AML) in the clinical. However, monotherapy with FLT3 inhibitor is usually accompanied by drug resistance. Dual inhibitors might be therapeutica
Autor:
Yu-Hsuan Li, Mei-Jung Lai, Wei-Cheng Wu, Jing-Ping Liou, Yi-Min Liu, Ssu-Ting Lien, Kai-Cheng Hsu, Shiow-Lin Pan, Mei-Chuan Chen, Yu-Hsuan Liao, I-Chung Chen
Publikováno v:
European journal of medicinal chemistry. 203
A major cause of failure of therapy in patients with non-small cell lung cancer (NSCLC) is development of acquired drug resistance leading to tumor recurrence and disease progression. In addition to the development of new generations of epidermal gro