Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Ssu Hsueh Tseng"'
Autor:
Hsin-Fang Tu, Margaret Wong, Ssu-Hsueh Tseng, Nattha Ingavat, Pola Olczak, Kin Israel Notarte, Chien-fu Hung, Richard B.S. Roden
Publikováno v:
Journal of Ovarian Research, Vol 17, Iss 1, Pp 1-15 (2024)
Abstract Background MUC16 is a heavily glycosylated cell surface mucin cleaved in the tumor microenvironment to shed CA125. CA125 is a serum biomarker expressed by > 95% of non-mucinous advanced stage epithelial ovarian cancers. MUC16/CA125 contribut
Externí odkaz:
https://doaj.org/article/ad877e31f2644c21920641ea86e35a8b
Autor:
Ravi K Anchoori, Ssu-Hsueh Tseng, Hua-Ling Tsai, Vikrant Palande, Michelle A Rudek, Richard B S Roden
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0305710 (2024)
There is an urgent unmet need for more targeted and effective treatments for advanced epithelial ovarian cancer (EOC). The emergence of drug resistance is a particular challenge, but small molecule covalent inhibitors have promise for difficult targe
Externí odkaz:
https://doaj.org/article/2db63bf16e0e4c7bacaecfd447382c57
Autor:
Yu-Jui Kung, Brandon Lam, Ssu-Hsueh Tseng, Alana MacDonald, Hsin-Fang Tu, Suyang Wang, John Lin, Ya Chea Tsai, T. C. Wu, Chien-Fu Hung
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-12 (2022)
Abstract Background For centuries, microbial-based agents have been investigated as a therapeutic modality for the treatment of cancer. In theory, these methods would be cheap to produce, broadly applicable in a wide array of cancer types, and could
Externí odkaz:
https://doaj.org/article/14e4a2b3d15f460e890051d6c0f95012
Autor:
Ravi K Anchoori, Vidyasagar Anchoori, Brandon Lam, Ssu-Hsueh Tseng, Samarjit Das, Fernanda Carrizo Velasquez, Balasubramanyam Karanam, Deepika Poddatoori, Ramesh Patnam, Michelle A Rudek, Yung-Nien Chang, Richard B S Roden
Publikováno v:
PLoS ONE, Vol 18, Iss 6, p e0285221 (2023)
Bortezomib has been successful for treatment of multiple myeloma, but not against solid tumors, and toxicities of neuropathy, thrombocytopenia and the emergence of resistance have triggered efforts to find alternative proteasome inhibitors. Bis-benzy
Externí odkaz:
https://doaj.org/article/9b4e3a1ede114e78983838d19f4e8731
Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-12 (2021)
Abstract Background Human Papillomavirus type 16 (HPV16) has been associated with a subset of head and neck cancers. Two HPV encoded oncogenic proteins, E6 and E7, are important for the malignant progression of HPV-associated cancers. A spontaneous H
Externí odkaz:
https://doaj.org/article/9f44f04f994e4196aea0025a3fdb9edb
Autor:
Ssu-Hsueh Tseng, Brandon Lam, Yu Jui Kung, John Lin, Li Liu, Ya Chea Tsai, Louise Ferrall, Richard B. S. Roden, T. C. Wu, Chien-Fu Hung
Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-8 (2021)
Abstract Background The spread of SARS-CoV-2, the virus that causes Coronavirus Disease 2019 (COVID-19), has been characterized as a worldwide pandemic. Currently, there are few preclinical animal models that suitably represent infection, as the main
Externí odkaz:
https://doaj.org/article/9c04d055d1bd4b0991cb3c2f12c981c4
Autor:
Chien-Fu Hung, Ssu-Hsueh Tseng, Brandon Lam, Max A Cheng, Emily Farmer, T-C Wu, Louise Ferrall, Yu Jui Kung, Ling Lim
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 4 (2022)
Externí odkaz:
https://doaj.org/article/83c0c196789a43ff9a33a2face4ce00b
Autor:
Tae Heung Kang, Chih-Ping Mao, Young Seob Kim, Tae Woo Kim, Andrew Yang, Brandon Lam, Ssu-Hsueh Tseng, Emily Farmer, Yeong-Min Park, Chien-Fu Hung
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-8 (2019)
Abstract The tumor microenvironment exists in a state of dynamic equilibrium, in which a balance of agonist and antagonist signals govern the anti-tumor immune responses. Previous studies have shown that chemotherapy could shift this balance in favor
Externí odkaz:
https://doaj.org/article/d7b47040938045bbad53169253d14929
Autor:
Brandon Lam, Yu Jui Kung, John Lin, Ssu-Hsueh Tseng, Ya Chea Tsai, Liangmei He, Gianni Castiglione, Emily Egbert, Elia J. Duh, Evan M. Bloch, Aaron A.R. Tobian, Aaron M. Milstone, Richard B.S. Roden, Tzyy-Choou Wu, Chien-Fu Hung
Publikováno v:
Cell Reports, Vol 37, Iss 3, Pp 109838- (2021)
Summary: As severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spreads, variants with enhanced virulence and transmissibility have emerged. Although in vitro systems allow rapid characterization, they do not fully recapitulate the dynamic i
Externí odkaz:
https://doaj.org/article/71e3dc14b5b146a39a33944e1256682a
Autor:
Ravi K Anchoori, Logan George, Ssu-Hsueh Tseng, Brandon Lam, Srinidhi Polkampally, Anjali D Amiano, Palmer Foran, Hannah Tsingine, Harideep Samanapally, Fernanda Carrizo Velasquez, Samarjit Das, Deyin Xing, Ahmad Bin Salam, Balasubramanyam Karanam, Chien-Fu Hung, Richard B S Roden
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0256937 (2021)
Bortezomib and the other licensed 20S proteasome inhibitors show robust activity against liquid tumors like multiple myeloma, but have disappointed against solid tumors including ovarian cancer. Consequently, interest is mounting in alternative non-p
Externí odkaz:
https://doaj.org/article/a191fb5eadb24586b1e67b55b0cdb07d