Výsledky vyhledávání - "Ss, Trofimov"

[The correction with nooglutil and L-pyroglutamyl-D-alanine amide of cognitive disorders in rats due to intrauterine hypoxia]

Autor: Ss, Trofimov, Ru, Ostrovskaia, Nm, Smol Nikova, Ep, Nemova, Tatiana Gudasheva, Ea, Kuznetsova, Ta, Voronina

Publikováno v: Europe PubMed Central

Novel nootropic compounds, nooglutyl (N-5-hydroxy(nicotinoyl)-L-glutamine acid, 25 mg/kg/day) and L-pyroglutamyl-D-alanine amide (1 mg/kg/day) administered intracutaneously from the 8th to 20th day of life prevent from movement hyperactivity in "open

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::878d889cbae616b708c1f4935b7c9323
https://pubmed.ncbi.nlm.nih.gov/8704601

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[A comparative analysis of the effect of nootropic preparations with different chemical structures on the failure of the escape reaction in rats]

Autor: An, Inozemtsev, Pl, Pragina, Fa, Firova, Ss, Trofimov, Tatiana Gudasheva, Na, Tushmalova, Ru, Ostrovskaia, Ta, Voronina

Publikováno v: Europe PubMed Central

The nootropic agents pyroglutamyl-D-alanine amide (TGS-20), mechlofenoxate, and mexidole versus piracetam were tested for their effects on the reversible impairments of cognitive brain functions, on the demolition of active avoidance responses in rat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6c735c076e42a6f4483047d28e15662f
https://pubmed.ncbi.nlm.nih.gov/7663285

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[The nooglutil correction of functional disorders of the central nervous system caused by prenatal alcoholization in rats]

Autor: Ss, Trofimov, Ru, Ostrovskaia, Nm, Smol Nikova, Iv, Khromova, Sv, Krapivin, Am, Krylova, Gi, Kovalev, Raul R Gainetdinov, Bi, Liubimov, Ta, Voronina

Publikováno v: Europe PubMed Central

Administration of ethanol (5 g/kg/day, per os) to the pregnant rats evoked delayed impairments of the learning and memory in the offspring. Prenatal alcoholization of the animals attenuated the habituation of the exploration behavior in open field, i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::48675c47a69cf215c5847440864e907e
https://pubmed.ncbi.nlm.nih.gov/1305426

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[L-pyroglutamyl-D-alanine amide normalizes the function of the developing brain damaged by antenatal alcoholization in rats]

Autor: Ru, Ostrovskaia, Ss, Trofimov, Tatiana Gudasheva, Nm, Smol Nikova, Ep, Nemova, Sv, Krapivin, Nm, Savchenko, Ml, Tsirenina, An, Ushakov, Ei, Mel Nik

Publikováno v: Europe PubMed Central

The effects of the synthetic dipeptide, L-pyroglutamyl-D-alaninamide (LPDA) were studied in the experiments on offspring of alcoholized during the pregnancy (5 g/kg/day) females. This dipeptide, which revealed the nootropic activity in previous exper

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f5a40d770c7795671be03360492e810a
https://pubmed.ncbi.nlm.nih.gov/2083361

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[Neuropharmacological properties of piracetam derivatives]

Autor: Ru, Ostrovskaia, Gm, Molodavkin, Ss, Trofimov, Popova RIa, Tatiana Gudasheva

Publikováno v: Europe PubMed Central

Piracetam and its 8 derivatives were studied in experiments on mice and rats with the use of standard neurotropic tests and nootropic activity tools. The electrophysiological index of GABA-ergic inhibition (the recovery cycle of cortical evoked poten

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5d4b4982b61c904d440084060360f422
https://pubmed.ncbi.nlm.nih.gov/6891272

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The novel substituted acylproline-containing dipeptide, GVS-111, promotes the restoration of learning and memory impaired by bilateral frontal lobectomy in rats

Autor: Ru, Ostrovskaya, Ga, Romanova, Ss, Trofimov, Tatiana Gudasheva, Ta, Voronina, Ja, Halikas, Sb, Seredenin

Publikováno v: Europe PubMed Central

The present study investigated the potential benefit of the ethyl ester of N-phenylacetylprolylglycine (GVS-111) on the model of bilateral frontal lobectomy (BFL) in rats. The animals in Experiment 1 were trained in an active avoidance task and subse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e27098b6a7f40c6ed22684e1b8291757
http://europepmc.org/abstract/med/9833021

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[Behavioral and electrophysiologic characteristics of a peptide analog of piracetam--L-pyroglutamyl-D-alanine amide]

Autor: Ru, Ostrovskaia, Tatiana Gudasheva, Ss, Trofimov, Ga, Romanova, Vp, Dobrynin

Publikováno v: Europe PubMed Central

The effect of L-pyroglutamyl-L-alanine amide, a structural analog of nootropil, was studied in the passive and active conditioned avoidance tests in rats. The compound (1 mg/kg, i. p.) was shown to be able to improve the performance in the shuttle-bo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::238cbaceafccd693d0c458e1ddfb1ab2
http://europepmc.org/abstract/med/3676493

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[The effect of the new nootropic dipeptide GVS-111 in different functional disorders of the escape reaction]

Autor: An, Inozemtsev, Ss, Trofimov, Gg, Borlikova, Fa, Firova, Ll, Pragina, Tatiana Gudasheva, Ru, Ostrovskaia, Na, Tushmalova, Ta, Voronina

Publikováno v: Europe PubMed Central

The authors studied the effect of a new nootropic agent with anxiolytic properties GVS-111 (ethyl ether N-phenylacetyl-L-prolylglycine) on formation of the avoidance reaction (AR) in rats and its functional disorders which were induced by two methods

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::354e05c64bf100bbdb896ab2ab7146d3
http://europepmc.org/abstract/med/9690067

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