Zobrazeno 1 - 10 of 63 pro vyhledávání: '"Ss, Sahota"'
1
Somatic mutation of bcl-6 genes can occur in the absence of V(H) mutations in chronic lymphocytic leukemia
Autor: Ss, Sahota, Davis Z, Tj, Hamblin, Freda Stevenson
Publikováno v: Europe PubMed Central
Somatic mutation in immunoglobulin variable (V) region genes occurs largely in the germinal center and, after neoplastic transformation, imprints V genes of B-cell tumors with the mutational history of the cell of origin. Recently, it has been found
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::67190b15e5b27680a0ecf6b07b53f4be
https://pubmed.ncbi.nlm.nih.gov/10828040
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2
VH gene analysis of clonally related IgM and IgG from human lymphoplasmacytoid B-cell tumors with chronic lymphocytic leukemia features and high serum monoclonal IgG
Autor: Ss, Sahota, Garand R, Bataille R, Aj, Smith, Freda Stevenson
Publikováno v: Scopus-Elsevier
Europe PubMed Central
An unusual group of human B-cell tumors with cellular features of chronic lymphocytic leukemia or lymphoplasmacytoid leukemia, together with high levels of a monoclonal IgG serum protein, has been investigated. Analysis of tumor-derived VH genes of n
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d3d737312b339b6a68c87a2e45c3b04e
https://pubmed.ncbi.nlm.nih.gov/9414290
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3
Ig VH gene mutational patterns indicate different tumor cell status in human myeloma and monoclonal gammopathy of undetermined significance
Autor: Ss, Sahota, Leo R, Tj, Hamblin, Freda Stevenson
Publikováno v: Europe PubMed Central
Plasma cell tumors display a wide spectrum of clinical progression, ranging from aggressive multiple myeloma to a benign form known as monoclonal gammopathy of undetermined significance (MGUS), which requires no treatment. Because both diseases invol
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a81cc33fbdef965d97bb8ff64c96ed5e
https://pubmed.ncbi.nlm.nih.gov/8555499
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6
Myeloma VL and VH gene sequences reveal a complementary imprint of antigen selection in tumor cells
Autor: Ss, Sahota, Leo R, Tj, Hamblin, Freda Stevenson
Publikováno v: Europe PubMed Central
In multiple myeloma, sequence studies of VH genes used to encode clonal Ig in neoplastic plasma cells have shown a common pattern of extensive somatic hypermutation. A further consistent feature of these VH sequences is a complete lack of intraclonal
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e206ef5cdddf619c50745bdde883fd7f
http://europepmc.org/abstract/med/8978295
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8
Akademický článek
The genomic landscape and clonal evolutionary trajectory of classical hairy cell leukemia.
Autor: Moreno Rueda LY; Tumour Immunogenetics Group, Cancer Sciences Unit, Faculty of Medicine, University of Southampton, Southampton, UK. lymoreno@mdanderson.org., Bryant D; Tumour Immunogenetics Group, Cancer Sciences Unit, Faculty of Medicine, University of Southampton, Southampton, UK., Tapper WJ; Genetic Epidemiology and Genomic Informatics Group, Human Genetics, Faculty of Medicine, University of Southampton, Southampton, UK., Weston-Bell NJ; Tumour Immunogenetics Group, Cancer Sciences Unit, Faculty of Medicine, University of Southampton, Southampton, UK., Wedge DC; Manchester Cancer Research Centre, University of Manchester, Manchester, UK., Ansari-Pour N; MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Sahota SS; Tumour Immunogenetics Group, Cancer Sciences Unit, Faculty of Medicine, University of Southampton, Southampton, UK.
Publikováno v: Leukemia [Leukemia] 2023 Apr; Vol. 37 (4), pp. 929-933. Date of Electronic Publication: 2023 Jan 28.
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9
Report
Single-cell exomes in an index case of amp1q21 multiple myeloma reveal more diverse mutanomes than the whole population.
Autor: Bryant D; Tumour Immunogenetics Group, Cancer Sciences Academic Unit, and., Tapper W; Human Development and Health Academic Unit, Faculty of Medicine, University of Southampton, Southampton, United Kingdom., Weston-Bell NJ; Tumour Immunogenetics Group, Cancer Sciences Academic Unit, and., Bolomsky A; Department of Medicine I, Wilhelminen Cancer Research Institute, Wilhelminen Hospital, Vienna, Austria; and., Song L; BGI Genomics, BGI-Shenzhen, Shenzhen, China., Xu S; BGI Genomics, BGI-Shenzhen, Shenzhen, China., Collins AR; Human Development and Health Academic Unit, Faculty of Medicine, University of Southampton, Southampton, United Kingdom., Zojer N; Department of Medicine I, Wilhelminen Cancer Research Institute, Wilhelminen Hospital, Vienna, Austria; and., Sahota SS; Tumour Immunogenetics Group, Cancer Sciences Academic Unit, and.
Publikováno v: Blood [Blood] 2018 Jul 12; Vol. 132 (2), pp. 232-235. Date of Electronic Publication: 2018 May 18.
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10
Akademický článek
Tracking B-Cell Repertoires and Clonal Histories in Normal and Malignant Lymphocytes.
Autor: Weston-Bell NJ; Tumour Immunogenetics Group, Cancer Sciences Academic Unit, Faculty of Medicine, University of Southampton, Southampton, UK.; University Hospital Southampton, Somers Cancer Research Building, MP824, Tremona Road, Southampton, SO16 6YD, UK., Cowan G; The King's Buildings, Ashworth Laboratories, Charlotte Auerbach Road, Edinburgh, EH9 3FL, UK., Sahota SS; Tumour Immunogenetics Group, Cancer Sciences Academic Unit, Faculty of Medicine, University of Southampton, Southampton, UK. S.S.Sahota@southampton.ac.uk.; University Hospital Southampton, Somers Cancer Research Building, MP824, Tremona Road, Southampton, SO16 6YD, UK. S.S.Sahota@southampton.ac.uk.
Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2017; Vol. 1623, pp. 281-301.
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