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pro vyhledávání: '"Sruthi Sritharan"'
Publikováno v:
Apoptosis : an international journal on programmed cell death. 27(9-10)
Cancer has presented to be the most challenging disease, contributing to one in six mortalities worldwide. The current treatment regimen involves multiple rounds of chemotherapy administration, alone or in combination. The treatment has adverse effec
Autor:
Kaliappan Ganesan, Sruthi Sritharan, Nageswaran Sivalingam, Ab Rouf War, Sri Harsha Vedulla, Jeyan Jayarajan, Sruthy Angandoor
Publikováno v:
Molecular biology reports. 47(10)
Cancer cells require higher levels of ATP for their sustained growth, proliferation, and chemoresistance. Mitochondrial matrix protein, C1qbp is upregulated in colon cancer cell lines. It protects the mitochondria from oxidative stress, by inhibiting
Publikováno v:
Life Sciences. 278:119527
Doxorubicin or Adriamycin, is one of the most widely used chemotherapeutic drug for treating a myriad of cancers. It induces cell death through multiple intracellular targets: reactive oxygen species generation, DNA-adduct formation, topoisomerase II