Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Sruthi Santhanam"'
Autor:
Sruthi Santhanam, Cheng Chen, Byeongtaek Oh, Kelly W. McConnell, Matine M. Azadian, Jainith J. Patel, Emily E. Gardner, Yuji Tanabe, Ada S. Y. Poon, Paul M. George
Publikováno v:
Advanced Electronic Materials, Vol 9, Iss 10, Pp n/a-n/a (2023)
Abstract Effective stroke recovery therapeutics remain limited. Stem cell therapies have yielded promising results, but the harsh ischemic environment of the post‐stroke brain reduces their therapeutic potential. Previously, a conductive polymer sy
Externí odkaz:
https://doaj.org/article/eff0ff77c57a4766ad822d4dc37eda0c
Autor:
Byeongtaek Oh, Sruthi Santhanam, Matine Azadian, Vishal Swaminathan, Alex G. Lee, Kelly W. McConnell, Alexa Levinson, Shang Song, Jainith J. Patel, Emily E. Gardner, Paul M. George
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Paul George and colleagues developed a conductive polymer system to enable stem cell delivery and electrical modulation in vivo. Employing this system improved functional stroke recovery in rodents and identified important repair pathways.
Externí odkaz:
https://doaj.org/article/e34baf38de8b485a92c16b327f8a2cce
Autor:
Byeongtaek Oh, Vishal Swaminathan, Andrey Malkovskiy, Sruthi Santhanam, Kelly McConnell, Paul M. George
Publikováno v:
Advanced Science, Vol 7, Iss 8, Pp n/a-n/a (2020)
Abstract Extracellular matrix (ECM) properties affect multiple cellular processes such as cell survival, proliferation, and protein synthesis. Thus, a polymeric‐cell delivery system with the ability to manipulate the extracellular environment can a
Externí odkaz:
https://doaj.org/article/d9c17adf7c184b478e3e5d2b9108bc4b
Autor:
Sruthi Santhanam, Vivian R. Feig, Kelly W. McConnell, Shang Song, Emily E. Gardner, Jainith J. Patel, Dingying Shan, Zhenan Bao, Paul M. George
Publikováno v:
Advanced Materials Technologies. 8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e6f4198bc53e5b3dfb71d0abd6871fa
https://doi.org/10.1002/admt.202201724
https://doi.org/10.1002/admt.202201724
Publikováno v:
Stroke. 53
Enhancing an endogenous stem cell response is a promising approach to improve stroke recovery. We have previously shown that a conductive polymer cannula system for human stem cell delivery and electrical stimulation of the post-stroke environment in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3301112144162253db04a85caca15e06
https://doi.org/10.1161/str.53.suppl_1.wp246
https://doi.org/10.1161/str.53.suppl_1.wp246
Autor:
Sruthi Santhanam, George J. Harocopos, Jessica J. Struckhoff, Bedia Begum Karakocak, Nathan Ravi, Ying-Bo Shui, Paul D. Hamilton
Publikováno v:
ACS applied bio materials. 2(1)
The vitreous humor of the eye is mainly composed of fibrillary collagen and semiflexible hyaluronic acid (HA). To mimic this macromolecular composition of the vitreous, we previously developed an injectable two-component hydrogel composed of a fibril
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd259c0135c9dd5aaa34fe70790a6df
https://pubmed.ncbi.nlm.nih.gov/35016332
https://pubmed.ncbi.nlm.nih.gov/35016332
Autor:
Byeongtaek Oh, Sruthi Santhanam, Matine Azadian, Vishal Swaminathan, Alex G. Lee, Kelly W. McConnell, Alexa Levinson, Shang Song, Jainith J. Patel, Emily E. Gardner, Paul M. George
Publikováno v:
Nature communications. 13(1)
Stroke is a leading cause of long-term disability worldwide, intensifying the need for effective recovery therapies. Stem cells are a promising stroke therapeutic, but creating ideal conditions for treatment is essential. Here we developed a conducti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b97a46c596958eb97d6a5fc26b3a4238
https://pubmed.ncbi.nlm.nih.gov/35292643
https://pubmed.ncbi.nlm.nih.gov/35292643
Autor:
Kelly McConnell, Sruthi Santhanam, Vishal Swaminathan, Byeongtaek Oh, Paul M. George, Andrey V. Malkovskiy
Publikováno v:
Advanced Science
Advanced Science, Vol 7, Iss 8, Pp n/a-n/a (2020)
Advanced Science, Vol 7, Iss 8, Pp n/a-n/a (2020)
Extracellular matrix (ECM) properties affect multiple cellular processes such as cell survival, proliferation, and protein synthesis. Thus, a polymeric‐cell delivery system with the ability to manipulate the extracellular environment can act as a f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c227e5721619fcd1e0b0729ec7fe1751
https://pubmed.ncbi.nlm.nih.gov/32328414
https://pubmed.ncbi.nlm.nih.gov/32328414
Autor:
Matine Azadian, Kathy Liu, Paul M. George, Lucia G Brunel, Zhuojun Huang, Zhenan Bao, Kelly McConnell, Sruthi Santhanam, Helen Tran, Vivian R. Feig
Publikováno v:
Adv Mater Technol
Injectable 3D cell scaffolds possessing both electrical conductivity and native tissue-level softness would provide a platform to leverage electric fields to manipulate stem cell behavior. Granular hydrogels, which combine jamming-induced elasticity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b4657910e0f77a3fe0aab073857f825
https://doi.org/10.1002/admt.202100162
https://doi.org/10.1002/admt.202100162
Publikováno v:
Acta Biomaterialia. 43:327-337
The vitreous humor of the eye is a biological hydrogel principally composed of collagen fibers interspersed with hyaluronic acid. Certain pathological conditions necessitate its removal and replacement. Current substitutes, like silicone oils and per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c053f3c894a04ffa10e4ee985a0093b
https://doi.org/10.1016/j.actbio.2016.07.051
https://doi.org/10.1016/j.actbio.2016.07.051