Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Srona Sengupta"'
Autor:
Michael D, Claiborne, Srona, Sengupta, Liang, Zhao, Matthew L, Arwood, Im-Meng, Sun, Jiayu, Wen, Elizabeth A, Thompson, Marisa, Mitchell-Flack, Marikki, Laiho, Jonathan D, Powell
Publikováno v:
Sci Immunol
Memory CD8(+) T cells are characterized by their ability to persist long after the initial antigen encounter and their capacity to generate a rapid recall response. Recent studies have identified a role for metabolic reprogramming and mitochondrial f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::04aaeb81d8e89df020b54b177e6f0a75
https://pubmed.ncbi.nlm.nih.gov/35622902
https://pubmed.ncbi.nlm.nih.gov/35622902
Autor:
Michael D. Claiborne, Srona Sengupta, Liang Zhao, Matthew L. Arwood, Im-Meng Sun, Jiayu Wen, Elizabeth A. Thompson, Marisa Mitchell-Flack, Marikki Laiho, Jonathan D. Powell
Publikováno v:
Science Immunology. 7
Memory CD8 + T cells are characterized by their ability to persist long after the initial antigen encounter and their capacity to generate a rapid recall response. Recent studies have identified a role for metabolic reprogramming and mitochondrial fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::758d0be04b079dd1383ee21983caf318
https://doi.org/10.1126/sciimmunol.abh4271
https://doi.org/10.1126/sciimmunol.abh4271
Autor:
Srona Sengupta, Nathan L. Board, Fengting Wu, Milica Moskovljevic, Jacqueline Douglass, Josephine Zhang, Bruce R. Reinhold, Jonathan Duke-Cohan, Jeanna Yu, Madison C. Reed, Yasmine Tabdili, Aitana Azurmendi, Emily J. Fray, Hao Zhang, Emily Han-Chung Hsiue, Katharine Jenike, Ya-Chi Ho, Sandra B. Gabelli, Kenneth W. Kinzler, Bert Vogelstein, Shibin Zhou, Janet D. Siliciano, Scheherazade Sadegh-Nasseri, Ellis L. Reinherz, Robert F. Siliciano
Publikováno v:
Proceedings of the National Academy of Sciences. 119
HIV-1 infection is incurable due to the persistence of the virus in a latent reservoir of resting memory CD4+ T cells. “Shock-and-kill” approaches that seek to induce HIV-1 gene expression, protein production, and subsequent targeting by the host
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd8b19af4a8d6bd0b5e3f8ff2b157dd
https://doi.org/10.1073/pnas.2123406119
https://doi.org/10.1073/pnas.2123406119
Autor:
Srona Sengupta, Marikki Laiho, Marisa Mitchell-Flack, Elizabeth A. Thompson, Jiayu Wen, Jonathan D. Powell, Liang Zhao, Michael D. Claiborne, Im-Meng Sun, Matthew L. Arwood
Memory CD8+ T cells are characterized by their ability to persist long after the initial antigen encounter and their ability to generate a rapid recall response. Recent studies have identified a role for metabolic reprogramming and mitochondrial func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f48cd3971d382f51bef9592b3d2b3f87
https://doi.org/10.1101/2021.11.10.468070
https://doi.org/10.1101/2021.11.10.468070
Autor:
Srona Sengupta, Robert F. Siliciano, Janet D. Siliciano, Steven G. Deeks, Andrew E. Timmons, Josephine Zhang, Scheherazade Sadegh-Nasseri, Weiming Yang, Tatiana Boronina, Rebecca Hoh, Jeanna Yu, James O. Wrabl, Aeryon Kim, Robert N. Cole, Madison C. Reed, Robin A. Welsh
Publikováno v:
SSRN Electronic Journal.
Distinct CD4+T cell epitopes have been associated with spontaneous control of HIV-1 replication, but analysis of antigen-dependent factors that influence epitope selection is lacking. To examine these factors, we used a cell-free antigen processing s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9473a686fb33ec42f4775245b8b4a2c
https://doi.org/10.2139/ssrn.3956653
https://doi.org/10.2139/ssrn.3956653
Autor:
Alexandra M. Bender, Janet D. Siliciano, Kyungyoon J. Kwon, Katherine M. Bruner, Hao Zhang, Christopher L. Nobles, Joshua T. Kufera, Gregory M. Laird, Steven G. Deeks, Ya Chi Ho, Annukka A.R. Antar, Lynn N. Bertagnolli, Frederic D. Bushman, Nikolas Wada, John R. Gregg, Srona Sengupta, Joseph B. Margolick, Subul A. Beg, Andrew E. Timmons, Adam A. Capoferri, Emily J. Fray, Katharine M. Jenike, Zheng Wang, Francesco R. Simonetti, Joel N. Blankson, Robert F. Siliciano
Publikováno v:
Nature
A stable latent reservoir for HIV-1 in resting CD4+ T cells is the principal barrier to a cure1-3. Curative strategies that target the reservoir are being tested4,5 and require accurate, scalable reservoir assays. The reservoir was defined with quant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20332f9fe8377a2db455ba3f4f29d45c
https://doi.org/10.1038/s41586-019-0898-8
https://doi.org/10.1038/s41586-019-0898-8
Autor:
Srona Sengupta, Robert F. Siliciano
Publikováno v:
Immunity. 48:872-895
Antiretroviral therapy can effectively block HIV-1 replication and prevent or reverse immunodeficiency in HIV-1-infected individuals. However, viral replication resumes within weeks of treatment interruption. The major barrier to a cure is a small po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fe103b1beb08848a398384463ff64be
https://doi.org/10.1016/j.immuni.2018.04.030
https://doi.org/10.1016/j.immuni.2018.04.030
Autor:
Rebecca Hoh, Andrew E. Timmons, Steven G. Deeks, Robert F. Siliciano, Janet D. Siliciano, Kyungyoon J. Kwon, Francesco R. Simonetti, Hao Zhang, Srona Sengupta
Publikováno v:
Science Translational Medicine. 12
The latent reservoir of HIV-1 in resting CD4+ T cells is a major barrier to cure. It is unclear whether the latent reservoir resides principally in particular subsets of CD4+ T cells, a finding that would have implications for understanding its stabi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1aa26d2b7e65341d5b11b781af7fdbcd
https://doi.org/10.1126/scitranslmed.aax6795
https://doi.org/10.1126/scitranslmed.aax6795
Autor:
Kyungyoon J, Kwon, Andrew E, Timmons, Srona, Sengupta, Francesco R, Simonetti, Hao, Zhang, Rebecca, Hoh, Steven G, Deeks, Janet D, Siliciano, Robert F, Siliciano
Publikováno v:
Sci Transl Med
The latent reservoir of HIV-1 in resting CD4+ T cells is a major barrier to cure. It is unclear whether the latent reservoir of HIV-1 resides principally in particular subsets of CD4+ T cells, a finding that would have implications for understanding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c200acfbc9d2997a41289e6424e0d503
https://pubmed.ncbi.nlm.nih.gov/31996465
https://pubmed.ncbi.nlm.nih.gov/31996465
Autor:
Srona Sengupta, Madison Reed, Jeanna Yu, Tatiana Boronina, Weiming Yang, Andrew Timmons, Rebecca Hoh, Steve Deeks, Robert N. Cole, Janet Siliciano, Robert Siliciano, Scheherazade Sadegh-Nasseri
Publikováno v:
The Journal of Immunology. 206:104.12-104.12
Certain CD4+T cell epitopes have been associated with immune control of HIV-1 replication and the presence of anti-Env neutralizing antibodies. However, it remains unclear what antigen-dependent factors influence the dominance of certain epitopes in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b3eda22d8cf9639772eef1f7dbcc988
https://doi.org/10.4049/jimmunol.206.supp.104.12
https://doi.org/10.4049/jimmunol.206.supp.104.12