Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Srividya Velagapudi"'
Autor:
Sarah Costantino, Alessandro Mengozzi, Srividya Velagapudi, Shafeeq Ahmed Mohammed, Era Gorica, Alexander Akhmedov, Alessia Mongelli, Nicola Riccardo Pugliese, Stefano Masi, Agostino Virdis, Andreas Hülsmeier, Christian Matthias Matter, Thorsten Hornemann, Giovanni Melina, Frank Ruschitzka, Thomas Felix Luscher, Francesco Paneni
Publikováno v:
Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-13 (2023)
Abstract Background Metabolic cardiomyopathy (MCM), characterized by intramyocardial lipid accumulation, drives the progression to heart failure with preserved ejection fraction (HFpEF). Although evidence suggests that the mammalian silent informatio
Externí odkaz:
https://doaj.org/article/54a8ca9133bf4bca90b873b095b4112e
Autor:
Srividya Velagapudi, Peter Schraml, Mustafa Yalcinkaya, Hella A. Bolck, Lucia Rohrer, Holger Moch, Arnold von Eckardstein
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 11, Pp 2188-2201 (2018)
Clear-cell renal cell carcinomas (ccRCCs) are characterized by inactivation of the von Hippel-Lindau (VHL) gene and intracellular lipid accumulation by unknown pathomechanisms. The immunochemical analysis of 356 RCCs revealed high abundance of apoA-I
Externí odkaz:
https://doaj.org/article/3c8ca98bf1194103a64c23f781da89b0
Autor:
Joel T. Haas, Jan Albert Kuivenhoven, Justina C. Wolters, Andrzej J. Rzepiela, Mathilde Varret, Ann Verhaegen, Valérie Carreau, Szymon Stoma, Anne Philippi, Alaa Othman, Jerome Robert, N. Dalila, Belle V. van Rosmalen, An Verrijken, Arnold von Eckardstein, Bart van de Sluis, Silvija Radosavljevic, Paolo Zanoni, Simon F. Norrelykke, Roger Meier, M. Yalcinkaya, Bart Staels, Andreas Geier, Lucia Rohrer, Michael Stebler, Michele Visentin, Antoine Rimbert, Catherine Boileau, Antonio Gallo, Melinde Wijers, Nicolette C. A. Huijkman, Steve E. Humphries, Jonas Weyler, Freerk van Dijk, Michaela Keel, Srividya Velagapudi, Jean-Pierre Rabès, Marieke Smit, Anne Tybjærg-Hansen, Adriaan van der Graaf, Luisa Vonghia, Yara Abou-Khalil, Sven Francque, Grigorios Panteloglou, Marta Futema, Luc Van Gaal
Publikováno v:
Zanoni, P, Panteloglou, G, Othman, A, Haas, J T, Meier, R, Rimbert, A, Futema, M, Khalil, Y A, Norrelykke, S F, Rzepiela, A J, Stoma, S, Stebler, M, Van Dijk, F, Wijers, M, Wolters, J C, Dalila, N, Huijkman, N C A, Smit, M, Gallo, A, Carreau, V, Philippi, A, Rabès, J P, Boileau, C, Visentin, M, Vonghia, L, Weyler, J, Francque, S, Verrijken, A, Verhaegen, A, Van Gaal, L, Van Der Graaf, A, Van Rosmalen, B V, Robert, J, Velagapudi, S, Yalcinkaya, M, Keel, M, Radosavljevic, S, Geier, A, Tybjaerg-Hansen, A, Varret, M, Rohrer, L, Humphries, S E, Staels, B, Van De Sluis, B, Kuivenhoven, J A & Von Eckardstein, A 2022, ' Posttranscriptional Regulation of the Human LDL Receptor by the U2-Spliceosome ', Circulation Research, vol. 130, no. 1, pp. 80-95 . https://doi.org/10.1161/CIRCRESAHA.120.318141
Circulation Research
Circulation Research, 2022, 130 (1), pp.80-95. ⟨10.1161/CIRCRESAHA.120.318141⟩
Circulation research
Circulation research, 130(1), 80-95. LIPPINCOTT WILLIAMS & WILKINS
Circulation Research
Circulation Research, 2022, 130 (1), pp.80-95. ⟨10.1161/CIRCRESAHA.120.318141⟩
Circulation research
Circulation research, 130(1), 80-95. LIPPINCOTT WILLIAMS & WILKINS
Background: The LDLR (low-density lipoprotein receptor) in the liver is the major determinant of LDL-cholesterol levels in human plasma. The discovery of genes that regulate the activity of LDLR helps to identify pathomechanisms of hypercholesterolem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e7252f24e599e74af7d4245ca33b8f0
https://curis.ku.dk/portal/da/publications/posttranscriptional-regulation-of-the-human-ldl-receptor-by-the-u2spliceosome(80ba810e-1e80-4fb5-8616-1532e1482dba).html
https://curis.ku.dk/portal/da/publications/posttranscriptional-regulation-of-the-human-ldl-receptor-by-the-u2spliceosome(80ba810e-1e80-4fb5-8616-1532e1482dba).html
Autor:
Bettina Hesse, Jerzy-Roch Nofer, Mustafa Yalcinkaya, Renate Feuerborn, Alexander Lukasz, Andreas J. Hülsmeier, Srividya Velagapudi, Mingxia Liu, Lucia Rohrer, John S. Parks, Francesco Potì, Markus Stoffel, Arnold von Eckardstein, Dongdong Wang, Manuela Simoni, Anton Potapenko, Damir Perisa, Grigorios Panteloglou, Christina Christoffersen
Publikováno v:
Arterioscler Thromb Vasc Biol
Objective: ApoM enriches S1P (sphingosine-1-phosphate) within HDL (high-density lipoproteins) and facilitates the activation of the S1P 1 (S1P receptor type 1) by S1P, thereby preserving endothelial barrier function. Many protective functions exerted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89ebb28b8484a2a6c4f305f747ab86c0
https://www.zora.uzh.ch/id/eprint/215359/
https://www.zora.uzh.ch/id/eprint/215359/
Autor:
Thorsten Hornemann, Alaa Othman, Przemyslaw Blyszczuk, Dongryeol Ryu, Thomas F. Lüscher, Sara Oppi, Zoran Rancic, Xi-Ming Yuan, Xu Wang, Martin Andreas Geiger, Ana Terezinha Guillaumon, Stefanie Nusser-Stein, Sokrates Stein, Maaike H. Oosterveer, Srividya Velagapudi, Liam J. Ward, A Jomard, Elena Osto, Vincenzo Marzolla, Kangmin Yang
Publikováno v:
European Heart Journal, 41(9), 995-1005. Oxford University Press
Aims Nuclear receptors and their cofactors regulate key pathophysiological processes in atherosclerosis development. The transcriptional activity of these nuclear receptors is controlled by the nuclear receptor corepressors (NCOR), scaffolding protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::602a72fee2b17394776100eb9b9aa7a4
https://doi.org/10.5167/uzh-175064
https://doi.org/10.5167/uzh-175064
Autor:
Hella A. Bolck, Arnold von Eckardstein, Peter Schraml, Srividya Velagapudi, Mustafa Yalcinkaya, Lucia Rohrer, Holger Moch
Publikováno v:
Journal of Lipid Research
Journal of Lipid Research, Vol 59, Iss 11, Pp 2188-2201 (2018)
Journal of Lipid Research, Vol 59, Iss 11, Pp 2188-2201 (2018)
Clear-cell renal cell carcinomas (ccRCCs) are characterized by inactivation of the von Hippel-Lindau (VHL) gene and intracellular lipid accumulation by unknown pathomechanisms. The immunochemical analysis of 356 RCCs revealed high abundance of apoA-I
Autor:
Joost Weyler, Grigorios Panteloglou, B. Van De Sluis, Joel T. Haas, Anne Tybjærg-Hansen, Luisa Vonghia, Ann Verhaegen, Catherine Boileau, Alaa Othman, A. Van Der Graaf, Anne Philippi, Marieke Smit, Sven Francque, Mathilde Varret, Jan Albert Kuivenhoven, Srividya Velagapudi, B.V. Van Rosmalen, L. Van Gaal, Y. Abou Khalil, Justina C. Wolters, Antoine Rimbert, Simon F. Norrelykke, Roger Meier, Bart Staels, Lucia Rohrer, Andrzej J. Rzepiela, Paolo Zanoni, Andreas Geier, Michaela Keel, Valérie Carreau, S.E. Humphries, Michael Stebler, M. Futema, Szymon Stoma, N. Dalila, Melinde Wijers, Nicolette C. A. Huijkman, An Verrijken, Antonio Gallo, Jean-Pierre Rabès, A. von Eckardstein, Silvija Radosavljevic, M. Yalcinkaya, F. van Dijk, Michele Visentin
Publikováno v:
Atherosclerosis. 315:e15
Publikováno v:
Atherosclerosis. 275
During their metabolism, all lipoproteins undergo endocytosis, either to be degraded intracellularly, for example in hepatocytes or macrophages, or to be re-secreted, for example in the course of transcytosis by endothelial cells. Moreover, there are
Autor:
Paolo Zanoni, Simon F. Norrelykke, Arnold von Eckardstein, Szymon Stoma, Srividya Velagapudi, Mustafa Yalcinkaya, Lucia Rohrer, Antonio Piemontese, Damir Perisa, Roger Meier, Michael Stebler, Andrzej J. Rzepiela
Objective— Low- and high-density lipoproteins (LDL and HDL) must pass the endothelial layer to exert pro- and antiatherogenic activities, respectively, within the vascular wall. However, the rate-limiting factors that mediate transendothelial trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f6dfe2df344f81a83e70f750ad84de2
https://www.zora.uzh.ch/id/eprint/138020/
https://www.zora.uzh.ch/id/eprint/138020/
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 36
In the reverse cholesterol transport pathway cholesterol acceptors like high density lipoproteins (HDL) and apolipoprotein A-I (apoA-I), must cross the endothelium to get access to the donor cells in the arterial initima. However, it is unknown how t