Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Srividya, Swaminathan"'
Autor:
Anil Kumar, Srividya Swaminathan
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/1fe7643d358e4286a718b84f6b0cde35
Autor:
Adeleh Taghi Khani, Anil Kumar, Ashly Sanchez Ortiz, Kelly C. Radecki, Soraya Aramburo, Sung June Lee, Zunsong Hu, Behzad Damirchi, Mary Y. Lorenson, Xiwei Wu, Zhaohui Gu, William Stohl, Ignacio Sanz, Eric Meffre, Markus Müschen, Stephen J. Forman, Jean L. Koff, Ameae M. Walker, Srividya Swaminathan
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
Malignant human B cells express autocrine prolactin (PRL), which has the potential to engage the long isoform and intermediate form of the PRL receptor to promote proliferation and/or survival.
Externí odkaz:
https://doaj.org/article/84ab9aaf43bd41779abbb7561b6c18e0
Autor:
Anil Kumar, Min Huang, Norman J. Lacayo, Holden T. Maecker, Stephen J. Forman, Srividya Swaminathan, Caroline Duault, Jianhua Yu, Steven T. Rosen, Anthony Chan, Martin Carroll, Adeleh Taghi Khani, Soraya Aramburo, Ashly Sanchez Ortiz, Sung June Lee, Tinisha McDonald, Kathleen M. Sakamoto, Christian Hurtz, Sarah K. Tasian, Lucy Ghoda, Guido Marcucci, Zhaohui Gu, Saro Armenian, Shai Izraeli, Chun-Wei Chen, Michael A. Caligiuri
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 5 (2023)
Background Type I interferons (IFN-Is), secreted by hematopoietic cells, drive immune surveillance of solid tumors. However, the mechanisms of suppression of IFN-I-driven immune responses in hematopoietic malignancies including B-cell acute lymphobla
Externí odkaz:
https://doaj.org/article/fe41859c6f9543c091bbe4f40f81980e
Autor:
Haribabu, Jebiti, Garisetti, Vasavi, Malekshah, Rahime Eshaghi, Srividya, Swaminathan, Gayathri, Dasararaju, Bhuvanesh, Nattamai, Mangalaraja, Ramalinga Viswanathan, Echeverria, Cesar, Karvembu, Ramasamy
Publikováno v:
In Journal of Molecular Structure 15 February 2022 1250 Part 2
Autor:
Daniel F. Liefwalker, Meital Ryan, Zhichao Wang, Khyatiben V. Pathak, Seema Plaisier, Vidhi Shah, Bobby Babra, Gabrielle S. Dewson, Ian K. Lai, Adriane R. Mosley, Patrick T. Fueger, Stephanie C. Casey, Lei Jiang, Patrick Pirrotte, Srividya Swaminathan, Rosalie C. Sears
Publikováno v:
Cancer & Metabolism, Vol 9, Iss 1, Pp 1-18 (2021)
Abstract Background Metabolic reprogramming is a central feature in many cancer subtypes and a hallmark of cancer. Many therapeutic strategies attempt to exploit this feature, often having unintended side effects on normal metabolic programs and limi
Externí odkaz:
https://doaj.org/article/7cd9c0d6710b49d0b9772c58fca67313
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a cytokine that drives the generation of myeloid cell subsets including neutrophils, monocytes, macrophages, and dendritic cells in response to stress, infections, and cancers. By modulatin
Externí odkaz:
https://doaj.org/article/ff47cd79d84f452fb7b7f33f497442ea
Autor:
Sharon S. Hori, Ling Tong, Srividya Swaminathan, Mariola Liebersbach, Jingjing Wang, Sanjiv S. Gambhir, Dean W. Felsher
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract The targeted inactivation of individual oncogenes can elicit regression of cancers through a phenomenon called oncogene addiction. Oncogene addiction is mediated by cell-autonomous and immune-dependent mechanisms. Therapeutic resistance to o
Externí odkaz:
https://doaj.org/article/5eaa4c551c6b436ebaa97bfaaabc2d0e
Autor:
Srividya Swaminathan, Aida S. Hansen, Line D. Heftdal, Renumathy Dhanasekaran, Anja Deutzmann, Wadie D. M. Fernandez, Daniel F. Liefwalker, Crista Horton, Adriane Mosley, Mariola Liebersbach, Holden T. Maecker, Dean W. Felsher
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Oncogene addiction is considered as a cancer cell-autonomous phenomenon, but can also influence the host immune system. Here the authors show that MYC-driven lymphomagenesis is associated with a block in the maturation and effector functions of natur
Externí odkaz:
https://doaj.org/article/e934ba6da0f2436b96b15ce1e0b4094b
Autor:
Anil Kumar, Sung June Lee, Qiao Liu, Anthony K.N. Chan, Sheela Pangeni Pokharel, Jianhua Yu, Chun-Wei Chen, Srividya Swaminathan
Publikováno v:
STAR Protocols, Vol 2, Iss 4, Pp 100874- (2021)
Summary: Cytotoxic natural killer cells kill tumors and infected cells. We carried out CRISPR-based gene editing and transcriptional regulation in hard-to-manipulate NK-92 cells. NK-92-based therapies were found to be safe and efficacious in preclini
Externí odkaz:
https://doaj.org/article/576f760e90424b94b161b522d97bd3a9
Autor:
Kuan-Hui Ethan Chen, Mrinal Ghosh, Lorena Rivera, Samuel Lin, Anil Kumar, Srividya Swaminathan, Mary Y. Lorenson, Ameae M. Walker
Publikováno v:
Translational Oncology, Vol 14, Iss 11, Pp 101195- (2021)
Previous work has shown systemic knockdown of the long form prolactin receptor (LFPRLR) in vivo markedly reduced metastasis in mouse models of breast cancer, but whether this translated to prolonged survival was unknown. Here we show that LFPRLR knoc
Externí odkaz:
https://doaj.org/article/d6419100560d4e10afdca6f53eb28280