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Simulation-Guided Engineering Enables a Functional Switch in Selinadiene Synthase toward Hydroxylation.

Autor: Srivastava PL; School of Chemistry, Cardiff University, Main Building, Park Place, Cardiff CF10 3AT, U.K., Johns ST; School of Biochemistry, University of Bristol, University Walk, Bristol BS8 1TD, U.K., Voice A; School of Biochemistry, University of Bristol, University Walk, Bristol BS8 1TD, U.K., Morley K; School of Biochemistry, University of Bristol, University Walk, Bristol BS8 1TD, U.K., Escorcia AM; School of Biochemistry, University of Bristol, University Walk, Bristol BS8 1TD, U.K., Miller DJ; School of Chemistry, Cardiff University, Main Building, Park Place, Cardiff CF10 3AT, U.K., Allemann RK; School of Chemistry, Cardiff University, Main Building, Park Place, Cardiff CF10 3AT, U.K., van der Kamp MW; School of Biochemistry, University of Bristol, University Walk, Bristol BS8 1TD, U.K.

Publikováno v: ACS catalysis [ACS Catal] 2024 Jul 09; Vol. 14 (14), pp. 11034-11043. Date of Electronic Publication: 2024 Jul 09 (Print Publication: 2024).

Production of non-natural terpenoids through chemoenzymatic synthesis using substrate analogs.

Autor: Srivastava PL; School of Chemistry, Cardiff University, Cardiff, United Kingdom., Johnson LA; School of Chemistry, Cardiff University, Cardiff, United Kingdom., Miller DJ; School of Chemistry, Cardiff University, Cardiff, United Kingdom., Allemann RK; School of Chemistry, Cardiff University, Cardiff, United Kingdom. Electronic address: allemannrk@cardiff.ac.uk.

Publikováno v: Methods in enzymology [Methods Enzymol] 2024; Vol. 699, pp. 207-230. Date of Electronic Publication: 2024 Apr 04.

Redesigning the Molecular Choreography to Prevent Hydroxylation in Germacradien-11-ol Synthase Catalysis.

Autor: Srivastava PL; School of Chemistry, Cardiff University, Main Building, Park Place, Cardiff CF10 3AT, United Kingdom., Escorcia AM; School of Biochemistry, University of Bristol, University Walk, Bristol BS8 1TD, United Kingdom., Huynh F; School of Chemistry, Cardiff University, Main Building, Park Place, Cardiff CF10 3AT, United Kingdom., Miller DJ; School of Chemistry, Cardiff University, Main Building, Park Place, Cardiff CF10 3AT, United Kingdom., Allemann RK; School of Chemistry, Cardiff University, Main Building, Park Place, Cardiff CF10 3AT, United Kingdom., van der Kamp MW; School of Biochemistry, University of Bristol, University Walk, Bristol BS8 1TD, United Kingdom.

Publikováno v: ACS catalysis [ACS Catal] 2021 Feb 05; Vol. 11 (3), pp. 1033-1041. Date of Electronic Publication: 2021 Jan 07.

Therapeutic potential of cyanobacterial pigment protein phycoerythrin: in silico and in vitro study of BACE1 interaction and in vivo Aβ reduction.

Autor: Chaubey MG; Department of Biotechnology, Shree A. N. Patel PG Institute of Science and Research, Sardar Patel University, Anand 388001, Gujarat, India., Patel SN; Post-Graduate Department of Biosciences, UGC-Centre of Advanced Study, Satellite Campus, Vadtal Road, Sardar Patel University, Bakrol, 388315 Anand, Gujarat, India., Rastogi RP; Post-Graduate Department of Biosciences, UGC-Centre of Advanced Study, Satellite Campus, Vadtal Road, Sardar Patel University, Bakrol, 388315 Anand, Gujarat, India., Srivastava PL; Symbiosis School of Biological Science, Symbiosis International (Deemed University), Lavale, 412115 Pune, Maharashtra, India., Singh AK; Zydus Research Centre, Sarkhej-Bavla N.H. No. 8A, Moraiya, Sanand, Ahmedabad 382210, India., Madamwar D; Post-Graduate Department of Biosciences, UGC-Centre of Advanced Study, Satellite Campus, Vadtal Road, Sardar Patel University, Bakrol, 388315 Anand, Gujarat, India., Singh NK; Department of Biotechnology, Shree A. N. Patel PG Institute of Science and Research, Sardar Patel University, Anand 388001, Gujarat, India. Electronic address: nirajbiotech@gmail.com.

Publikováno v: International journal of biological macromolecules [Int J Biol Macromol] 2019 Aug 01; Vol. 134, pp. 368-378. Date of Electronic Publication: 2019 May 03.