Mono‐ and Di‐Fucosylated Glycans of the Parasitic Worm S. mansoni are Recognized Differently by the Innate Immune Receptor DC‐SIGN.

Autor: Srivastava, Apoorva D.¹ (AUTHOR), Unione, Luca¹ (AUTHOR), Wolfert, Margreet A.^1,2 (AUTHOR), Valverde, Pablo³ (AUTHOR), Ardá, Ana³ (AUTHOR), Jiménez‐Barbero, Jesús^3,4,5 (AUTHOR), Boons, Geert‐Jan^1,2,6 (AUTHOR) g.j.p.h.boons@uu.nl

Publikováno v: Chemistry - A European Journal. Dec2020, Vol. 26 Issue 67, p15605-15612. 8p.

Ion-Mobility Spectrometry Can Assign Exact Fucosyl Positions in Glycans and Prevent Misinterpretation of Mass-Spectrometry Data After Gas-Phase Rearrangement

Autor: Sastre Toraño, Javier, Gagarinov, Ivan A, Vos, Gaël M, Broszeit, Frederik, Srivastava, Apoorva D, Palmer, Martin, Langridge, James I, Aizpurua-Olaizola, Oier, Somovilla, Victor J, Boons, Geert-Jan, Afd Chemical Biology and Drug Discovery, Sub Chemical Biology and Drug Discovery, Chemical Biology and Drug Discovery

Publikováno v: Angewandte Chemie-International Edition, 58(49), 17616. John Wiley and Sons Ltd

The fucosylation of glycans leads to diverse structures and is associated with many biological and disease processes. The exact determination of fucoside positions by tandem mass spectrometry (MS/MS) is complicated because rearrangements in the gas p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cd0d32f131af5713afcb3396341b551
https://dspace.library.uu.nl/handle/1874/389151

A Chemoenzymatic Approach for the Preparation of Asymmetric Bi-, Tri- and Tetra-Antennary N-Glycans from a Common Precursor

Autor: Gagarinov, Ivan A, Li, Tiehai, Sastre Torano, Javier, Caval, Tomislav, Srivastava, Apoorva D, Kruijtzer, John A W, Heck, Albert J R, Boons, Geert-Jan

Progress in glycoscience is hampered by a lack of well-defined complex oligosaccharide standards that are needed to fabricate the next generation of microarrays, to develop analytical protocols to determine exact structures of isolated glycans, and t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______101::ffaa827773766c978e2a621e59844c1a
https://dspace.library.uu.nl/handle/1874/428645

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Ion-Mobility Spectrometry Can Assign Exact Fucosyl Positions in Glycans and Prevent Misinterpretation of Mass-Spectrometry Data After Gas-Phase Rearrangement.

Autor: Sastre Toraño J; Department of Chemical Biology and Drug Discovery, Utrecht University, Universiteitsweg 99, 3584, CG, Utrecht, The Netherlands., Gagarinov IA; Department of Chemical Biology and Drug Discovery, Utrecht University, Universiteitsweg 99, 3584, CG, Utrecht, The Netherlands., Vos GM; Department of Chemical Biology and Drug Discovery, Utrecht University, Universiteitsweg 99, 3584, CG, Utrecht, The Netherlands., Broszeit F; Department of Chemical Biology and Drug Discovery, Utrecht University, Universiteitsweg 99, 3584, CG, Utrecht, The Netherlands., Srivastava AD; Department of Chemical Biology and Drug Discovery, Utrecht University, Universiteitsweg 99, 3584, CG, Utrecht, The Netherlands., Palmer M; Waters Corporation, Stamford Avenue, Altrincham Road, SK9 4AX, Wilmslow, UK., Langridge JI; Waters Corporation, Stamford Avenue, Altrincham Road, SK9 4AX, Wilmslow, UK., Aizpurua-Olaizola O; Department of Chemical Biology and Drug Discovery, Utrecht University, Universiteitsweg 99, 3584, CG, Utrecht, The Netherlands., Somovilla VJ; Department of Chemical Biology and Drug Discovery, Utrecht University, Universiteitsweg 99, 3584, CG, Utrecht, The Netherlands., Boons GJ; Department of Chemical Biology and Drug Discovery, Utrecht University, Universiteitsweg 99, 3584, CG, Utrecht, The Netherlands.; Complex Carbohydrate Research Center and Department of Chemistry, University of Georgia, 315 Riverbend Road, Athens, GA, 30602, USA.

Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2019 Dec 02; Vol. 58 (49), pp. 17616-17620. Date of Electronic Publication: 2019 Oct 22.