Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Srivastav Ranganathan"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/810de3a60e3a4ee2af0d2e2b2333bbb4
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/8c584d6b7e444a0fb6405c0e280eef9d
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 5, p e1010067 (2022)
Phase separation of biomolecules could be mediated by both specific and non-specific interactions. How the interplay between non-specific and specific interactions along with polymer entropy influences phase separation is an open question. We address
Externí odkaz:
https://doaj.org/article/be49d14b454646b2b95c2cabc8df0fba
Publikováno v:
eLife, Vol 9 (2020)
Multivalent biopolymers phase separate into membrane-less organelles (MLOs) which exhibit liquid-like behavior. Here, we explore formation of prototypical MOs from multivalent proteins on various time and length scales and show that the kinetically a
Externí odkaz:
https://doaj.org/article/89dc3dbf0400424ebc3a6791029898e9
Autor:
Srivastav Ranganathan, Pradeep K Singh, Uday Singh, Praful S Singru, Ranjith Padinhateeri, Samir K Maji
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e31924 (2012)
Peptide/protein hormones could be stored as non-toxic amyloid-like structures in pituitary secretory granules. ACTH and β-endorphin are two of the important peptide hormones that get co-stored in the pituitary secretory granules. Here, we study mole
Externí odkaz:
https://doaj.org/article/1e4dc25f2dac4a138ec7597bdfafa5b0
Assemblies of multivalent RNA-binding protein FUS can exist in the functional liquid-like state as well as less dynamic and potentially toxic amyloid- and hydrogel-like states. How could then cells form liquid-like condensates while avoiding their tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de4c415c08279cca0cc21adb008ca348
https://doi.org/10.1101/2022.09.15.508150
https://doi.org/10.1101/2022.09.15.508150
Publikováno v:
Essays Biochem
Biomolecular condensates are functional assemblies, which can enrich intrinsically disordered proteins (IDPs) and/or RNAs at concentrations that are orders of magnitude higher than the bulk. In their native functional state, these structures can exis
Publikováno v:
Biophysical Journal. 122:337a
Publikováno v:
Biophysical journal. 121(14)
Many RNA-binding proteins (RBPs) that assemble into membraneless organelles have a common architecture including disordered prion-like domain (PLD) and folded RNA-binding domain (RBD). An enrichment of PLD within the condensed phase gives rise to for
Many RNA-binding proteins (RBPs) that assemble into membraneless organelles, have a common architecture including disordered prion-like domain (PLD) and folded RNA-binding domain (RBD). An enrichment of PLD within the condensed phase gives rise to fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5af8147d0d3d90d8efe1a2af3cfcd1c4
https://doi.org/10.1101/2021.11.15.468745
https://doi.org/10.1101/2021.11.15.468745