Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Srisaila Basavappa"'
Autor:
Hui Zhang, Uma Sundaram, Srisaila Basavappa, David I. Yule, Sreesatya Raju Vulapalli, Steven Coon
Publikováno v:
Journal of Cellular Physiology. 202:21-31
Small intestinal crypt cells play a critical role in modulating Cl- secretion during digestion. The types of Cl- channels mediating Cl- secretion in the small intestine was investigated using the intestinal epithelial cell line, IEC-18, which was der
Publikováno v:
Biochemical and Biophysical Research Communications. 308:759-763
In most mammalian cells, regulatory volume decrease (RVD) is mediated by swelling-activated Cl(-) and K(+) channels. Previous studies in the human neuroblastoma cell line CHP-100 have demonstrated that exposure to hypoosmotic solutions activates Cl(-
Autor:
Vazhaikkurichi M. Rajendran, Emile L. Boulpaep, Sadasivan Vidyasagar, Henry J. Binder, William J. Joiner, Keith Nehrke, Selvi Krishnan, Srisaila Basavappa
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 285:G185-G196
Colonic K+secretion stimulated by cholinergic agents requires activation of muscarinic receptors and the release of intracellular Ca2+. However, the precise mechanisms by which this rise in Ca2+leads to K+efflux across the apical membrane are poorly
Publikováno v:
Journal of Cellular Physiology. 189:316-322
The effects of calcium, calmodulin, protein kinase C (PKC) and protein tyrosine kinase (PTK) modulators were examined on the volume-activated taurine efflux in the erythroleukemia cell line K562. Exposure to hypoosmotic solution significantly increas
Publikováno v:
Journal of General Physiology. 113:441-456
Swelling-induced activation of the outwardly rectifying anion current, ICl, swell, is modulated by intracellular ATP. The mechanisms by which ATP controls channel activation, however, are unknown. Whole cell patch clamp was employed to begin addressi
Publikováno v:
Biochemical and Biophysical Research Communications. 254:699-702
Activation of L-type calcium channels in the neuroendocrine, cholecytstokinin-secreting cell line, STC-1, is vital for secretion of CCK. In the present study, the regulation of L-type Ca 2+ channels by cAMP and Ca 2+ calmodulin dependent protein kina
Autor:
Chiun Chien Huang, Ali Mobasheri, Samir Al-Adawi, R. J. Errington, Srisaila Basavappa, J. Clive Ellory
Publikováno v:
Journal of Cellular Physiology. 174:145-153
The Na+ pump (Na+, K+-ATPase) has been implicated in the regulation of many cellular functions, including cell volume regulation. The effects of inhibiting Na+ pump activity on cell volume and taurine efflux were evaluated in the human neuroblastoma
Autor:
Srisaila Basavappa, J. C. Ellory
Publikováno v:
Molecular Neurobiology. 13:137-153
Regulation of cell volume is an essential function of most mammalian cells. In the cells of the central nervous system, maintenance of cell osmolarity and, hence, volume, is particularly crucial because of the restrictive nature of the skull. Cell vo
Publikováno v:
Journal of Cellular Physiology. 167:354-358
The effects of hypotonic shock on cell volume, taurine influx and efflux were examined in the human erythroleukemic cell line K562. Cells exposed to hypotonic solutions exhibited a regulatory volume decrease (RVD) following rapid increases in cell vo
Autor:
V. Prpic, Allen W. Mangel, Srisaila Basavappa, Thomas W. Gettys, W. D. Capel, Rodger A. Liddle, L. Scott
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 270:G291-G297
Previously, it has been shown that an increase in adenosine 3',5'-cyclic monophosphate (cAMP) levels stimulates intestinal secretion of cholecystokinin (CCK); however, the mechanisms for increasing intracellular cAMP levels are not known. Using the C