Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sriram Gunda"'
Publikováno v:
AAPS PharmSciTech. 15:1454-1467
The purpose of this study was to develop a clear aqueous mixed nanomicellar formulation (MNF) of dexamethasone utilizing both D-α-tocopherol polyethylene glycol-1000 succinate (Vit E TPGS) and octoxynol-40 (Oc-40). In this study, Vit E TPGS and Oc-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1e2171d3214b6a836e8a5dd5d9ef695
https://doi.org/10.1208/s12249-014-0159-y
https://doi.org/10.1208/s12249-014-0159-y
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 40:325-334
Ganciclovir (GCV) is utilized as an anti-herpetic agent. Reports from our laboratory have suggested that dipeptide ester prodrugs of GCV exhibit high affinity towards the oligopeptide transporter hPEPT1 and therefore seem to be promising candidates f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76f554f595ea82efe94b8011cbadaed3
https://doi.org/10.1007/s13318-014-0200-2
https://doi.org/10.1007/s13318-014-0200-2
Publikováno v:
Pharmaceutical Research. 26:1270-1282
The objectives were (i) to test in vivo functional activity of MRP2 on rabbit corneal epithelium and (ii) to evaluate modulation of P-gp and MRP2 mediated efflux of erythromycin when co-administered with corticosteroids.Cultured rabbit primary cornea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ca40fb8e66a4fb6a3ded156947d3c07
https://doi.org/10.1007/s11095-008-9741-x
https://doi.org/10.1007/s11095-008-9741-x
Publikováno v:
International Journal of Pharmaceutics. 359:15-24
To evaluate in vivo corneal absorption of the amino acid prodrugs of acyclovir (ACV) using a topical well model and microdialysis in rabbits.Stability of L-alanine-ACV (AACV), L-serine-ACV (SACV), L-isoleucine-ACV (IACV), gamma-glutamate-ACV (EACV) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9956a1422088f675aa9df4658182f069
https://doi.org/10.1016/j.ijpharm.2008.03.015
https://doi.org/10.1016/j.ijpharm.2008.03.015
Autor:
Sriram Gunda, Ashim K. Mitra, Xiaodong Zhu, Kumar G. Janoria, Sudharshan Hariharan, Dhananjay Pal
Publikováno v:
Current Eye Research. 31:811-824
To investigate the functional expression of a carrier-mediated transport mechanism for riboflavin (vitamin B2) across cultured rabbit primary corneal epithelial cells (rPCECs) and intact rabbit cornea. The secondary objective was to understand the ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bbe3432df7c2e18ee6b1d7234608d43
https://doi.org/10.1080/02713680600899655
https://doi.org/10.1080/02713680600899655
Publikováno v:
Current Eye Research. 26:175-183
The major objectives were to investigate functional expression of nucleoside transporters on the rabbit cornea and to delineate mechanism of corneal permeation of acyclovir (ACV) and idoxuridine (IDU). Methods. Transport studies were conducted with i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2ff324204386b7ee8d12d3d9f3d2787
https://doi.org/10.1076/ceyr.26.3.175.14895
https://doi.org/10.1076/ceyr.26.3.175.14895
The objective of this study was to develop a clear, aqueous rapamycin-loaded mixed nanomicellar formulations (MNFs) for the back-of-the-eye delivery. MNF of rapamycin (0.2%) was prepared with vitamin E tocopherol polyethylene glycol succinate (TPGS)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa405e3e6428bb719be11b8ace5902d7
https://europepmc.org/articles/PMC4444623/
https://europepmc.org/articles/PMC4444623/
A novel, fast and sensitive 3200 QTRAP LC–MS/MS method was validated for rapamycin analysis in the rabbit eye following 0.2% administration of nanomicellar eye drop formulation. The LC–MS/MS technique was developed with electrospray ionization (E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a74c7d7681e0ec1316e40eb2dfabab13
https://europepmc.org/articles/PMC3597233/
https://europepmc.org/articles/PMC3597233/
Publikováno v:
Bioanalysis. 2(3)
The unique anatomy and physiology of the eye present many challenges to the successful development and delivery of ophthalmic drugs. Any therapeutic strategy developed to control the progression of anterior and posterior segment diseases requires con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a700d9bbf23f51b0073b7548ebfd86a
https://pubmed.ncbi.nlm.nih.gov/21083257
https://pubmed.ncbi.nlm.nih.gov/21083257
Publikováno v:
Ocular Transporters In Ophthalmic Diseases And Drug Delivery ISBN: 9781588299581
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::284dcb2e65256fab20936de7fd3050cc
https://doi.org/10.1007/978-1-59745-375-2_21
https://doi.org/10.1007/978-1-59745-375-2_21