Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Sriram, Sokalingam"'
Publikováno v:
Biotechnology and Bioprocess Engineering. 25:734-741
Structural information of Fc-Fc receptor interaction may contribute to the design of drugs or therapeutic antibodies associated with the interaction. Computational protein-protein docking can be employed in structural study of protein-protein interac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::811d38558c849b52ea02a49d8f1e3101
https://doi.org/10.1007/s12257-020-0050-5
https://doi.org/10.1007/s12257-020-0050-5
Autor:
Selvi, B. Ruthrotha, Batta, Kiran, Kishore, A. Hari, Mantelingu, Kempegowda, Varier, Radhika A., Balasubramanyam, Karanam, Pradhan, Suman Kalyan, Dasgupta, Dipak, Sriram, Sokalingam, Agrawal, Shipra, Kundu, Tapas K.
Publikováno v:
In Journal of Biological Chemistry 5 March 2010 285(10):7143-7152
Publikováno v:
Journal of Industrial and Engineering Chemistry. 78:344-351
Lipocalins are potential targets for drug development, and therefore it is important to understand the common and distinct features of their ligand-binding sites. Here, the sequence and structural features of ligand-binding sites in kernel and outlie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::777d41640d6835ef1895f22c8f534cae
https://doi.org/10.1016/j.jiec.2019.05.035
https://doi.org/10.1016/j.jiec.2019.05.035
Autor:
Lawrence Matiski, Xiaowei Liu, Shuoxing Jiang, Theresa Yip, Li Liu, Fei Zhang, Hao Yan, Ryan Rodriguez Del Villar, Xiaodong Qi, Sriram Sokalingam, Yung Chang
Publikováno v:
ACS nano. 14(4)
Rapid developments in nucleic acid nanotechnology have enabled the rational design and construction of self-assembling DNA and RNA nanostructures that are highly programmable. We recently developed a replicable single-stranded RNA origami (RNA-OG) te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebade7d61fb53138dc38d79b0b851502
https://pubmed.ncbi.nlm.nih.gov/32275389
https://pubmed.ncbi.nlm.nih.gov/32275389
Autor:
Nagasundarapandian Soundrarajan, Sriram Sokalingam, Govindan Raghunathan, Nediljko Budisa, Hyun-Jong Paik, Tae Hyeon Yoo, Sun-Gu Lee
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46741 (2012)
N-terminal site-specific modification of a protein has many advantages over methods targeting internal positions, but it is not easy to install reactive groups onto a protein in an N-terminal specific manner. We here report a strategy to incorporate
Externí odkaz:
https://doaj.org/article/f058328453064eb9ae2ddef4b5557d8f
Autor:
Govindan Raghunathan, Nagasundarapandian Soundrarajan, Sriram Sokalingam, Hyungdon Yun, Sun-Gu Lee
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51510 (2012)
Diversification of protein sequence-structure space is a major concern in protein engineering. Deletion mutagenesis can generate a protein sequence-structure space different from substitution mutagenesis mediated space, but it has not been widely use
Externí odkaz:
https://doaj.org/article/abc03c980ff54994a8a7cc4938bcb915
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40410 (2012)
Two positively charged basic amino acids, arginine and lysine, are mostly exposed to protein surface, and play important roles in protein stability by forming electrostatic interactions. In particular, the guanidinium group of arginine allows interac
Externí odkaz:
https://doaj.org/article/d58ed458687c4243bbd997f384b54da1
Publikováno v:
Journal of Industrial and Engineering Chemistry. 67:293-300
Lipocalins are diverse group of small extracellular proteins found in various organisms. In this study, members of 10 non-homologous lipocalin–ligand crystal complex structures were remodeled using rigid and flexible ligand modes to validate the pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90d39950054b109d770a142af6d5eff0
https://doi.org/10.1016/j.jiec.2018.06.041
https://doi.org/10.1016/j.jiec.2018.06.041
Publikováno v:
Biotechnology and Bioprocess Engineering. 23:158-167
Lipocalins are proteins with highly homologous structures but diverse sequences that are potential candidates for scaffold protein engineering with novel ligand-binding functions. Numerous crystal structures of lipocalin-ligand complexes have been id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90ee94e71c0b00a458b86a3d1ef597ab
https://doi.org/10.1007/s12257-018-0032-z
https://doi.org/10.1007/s12257-018-0032-z
Autor:
Sriram Sokalingam, Jung Rae Kim, Ganapathiraman Munussami, Sun-Gu Lee, Sungwook Chung, Selvakumar Edwardraja
Publikováno v:
Korean Journal of Chemical Engineering. 35:717-724
Cystatins and lipocalins have attracted considerable interest for their potential applications in non-immunoglobulin protein scaffold engineering. In the present study, their potential homologs were screened computationally from non-redundant protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9043bcc833c44920d8fad0e7c952ebe9
https://doi.org/10.1007/s11814-017-0350-4
https://doi.org/10.1007/s11814-017-0350-4