Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Sriparna Ghosal"'
Autor:
Sriparna Ghosal, Elias Gebara, Eva Ramos-Fernández, Alessandro Chioino, Jocelyn Grosse, Isabelle Guillot de Suduiraut, Olivia Zanoletti, Bernard Schneider, Antonio Zorzano, Simone Astori, Carmen Sandi
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112776- (2023)
Summary: The nucleus accumbens (NAc) is a brain hub regulating motivated behaviors, including social competitiveness. Mitochondrial function in the NAc links anxiety with social competitiveness, and the mitochondrial fusion protein mitofusin 2 (Mfn2)
Externí odkaz:
https://doaj.org/article/b2e0e84f146d4e059949d56b1b7283d3
Autor:
Sriparna Ghosal, Catharine H. Duman, Rong-Jian Liu, Min Wu, Rosemarie Terwilliger, Matthew J. Girgenti, Eric Wohleb, Manoela V. Fogaca, Emily M. Teichman, Brendan Hare, Ronald S. Duman
Publikováno v:
Neurobiology of Disease, Vol 134, Iss , Pp - (2020)
Dysfunction of medial prefrontal cortex (mPFC) in association with imbalance of inhibitory and excitatory neurotransmission has been implicated in depression. However, the precise cellular mechanisms underlying this imbalance, particularly for GABAer
Externí odkaz:
https://doaj.org/article/ddd4cb39631a4c748e757426ea0a3eb8
Publikováno v:
Neurobiology of Disease, Vol 100, Iss , Pp 1-8 (2017)
Impaired fear extinction contributes to the persistence of post-traumatic stress disorder (PTSD), and can be utilized for the study of novel therapeutic agents. Glutamate plays an important role in the formation of traumatic memories, and in the path
Externí odkaz:
https://doaj.org/article/8963526579a8490da9860d55a278d748
Publikováno v:
Chronic Stress, Vol 1 (2017)
Stress-associated disorders, including depression and anxiety, impact nearly 20% of individuals in the United States. The social, health, and economic burden imposed by stress-associated disorders requires in depth research efforts to identify suitab
Externí odkaz:
https://doaj.org/article/a58ede43d50d479684408a3a55781c9c
Autor:
Laia, Morató, Simone, Astori, Ioannis, Zalachoras, Joao, Rodrigues, Sriparna, Ghosal, Wei, Huang, Isabelle, Guillot de Suduiraut, Jocelyn, Grosse, Olivia, Zanoletti, Lei, Cao, Johan, Auwerx, Carmen, Sandi
Publikováno v:
Science advances. 8(9)
Obesity is frequently associated with impairments in the social domain, and stress at puberty can lead to long-lasting changes in visceral fat deposition and in social behaviors. However, whether stress-induced changes in adipose tissue can affect fa
Autor:
Sriparna Ghosal, Elias Gebara, Eva Ramos-Fernández, Alessandro Chioino, Jocelyn Grosse, Bernard Schneider, Antonio Zorzano, Simone Astori, Carmen Sandi
The nucleus accumbens (NAc) is a brain hub regulating motivated behaviors, including social competitiveness. Mitochondrial function in the NAc is critically implicated in the association between anxiety and social competitiveness, and the mitochondri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3aa66d6663debcc7d209cf58646285f
Autor:
Eric S. Wohleb, Matthew J. Girgenti, Sriparna Ghosal, Sameet Mehta, Ronald S. Duman, Manoela V. Fogaça
Publikováno v:
Translational Psychiatry
Translational Psychiatry, Vol 9, Iss 1, Pp 1-13 (2019)
Translational Psychiatry, Vol 9, Iss 1, Pp 1-13 (2019)
γ-aminobutyric acid (GABA) inhibitory interneurons play a key role in efferent and afferent control of principle neuron activity in the prefrontal cortex (PFC), thereby regulating signal integrity of cognitive and behavioral processes. Recent eviden
Autor:
Ashley E. Lepack, Wenzhu Yue, Matthew J. Girgenti, Eunyoung Bang, Brendan D. Hare, Sriparna Ghosal, Ronald S. Duman
Publikováno v:
Biological Psychiatry. 83:29-37
Background Brain-derived neurotrophic factor (BDNF) plays a key role in the pathophysiology and treatment of depression. Recent clinical studies demonstrate that scopolamine, a nonselective muscarinic acetylcholine receptor antagonist, produces rapid
Autor:
Jessie R. Scheimann, Maureen E. Fitzgerald, Parinaz Mahbod, Jenny Tong, James P. Herman, Diego Perez-Tilve, Benjamin A. Packard, Rachel Morano, Sriparna Ghosal, Eric P. Smith
Publikováno v:
Endocrinology. 159:388-399
Ghrelin is a 28-amino acid polypeptide that regulates feeding, glucose metabolism, and emotionality (stress, anxiety, and depression). Plasma ghrelin circulates as desacyl ghrelin (DAG) or, in an acylated form, acyl ghrelin (AG), through the actions
Publikováno v:
Current Opinion in Behavioral Sciences. 14:1-8
Psychiatric diseases, notably major depression, are associated with imbalance of excitatory and inhibitory neurotransmission within the prefrontal cortex (PFC) and related limbic brain circuitry. In many cases these illnesses are precipitated or exac