Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Sripad Gunwar"'
Autor:
Sripad Gunwar, Milton E. Noelken, Billy G. Hudson, Olga Bondar, Kai-Olaf Netzer, Yoshifumi Ninomiya, Yoshikazu Sado, Dorin-Bogdan Borza, Narinder Singh, Ariel Boutaud
Publikováno v:
Journal of Biological Chemistry. 275:30716-30724
The ultrafiltration function of the glomerular basement membrane (GBM) of the kidney is impaired in genetic and acquired diseases that affect type IV collagen. The GBM is composed of five (alpha1 to alpha5) of the six chains of type IV collagen, orga
Autor:
Jan P. M. Langeveld, Anu Leinonen, Ariel Boutaud, Parvin Todd, Kai-Olaf Netzer, Dorin-Bogdan Borza, Sripad Gunwar, Billy G. Hudson
Publikováno v:
Journal of Biological Chemistry. 274:11267-11274
The Goodpasture (GP) autoantigen has been identified as the alpha3(IV) collagen chain, one of six homologous chains designated alpha1-alpha6 that comprise type IV collagen (Hudson, B. G., Reeders, S. T., and Tryggvason, K. (1993) J. Biol. Chem. 268,
Publikováno v:
Kidney International. 55:926-935
Goodpasture antigen: Expression of the full-length α3(IV) chain of collagen IV and localization of epitopes exclusively to the noncollagenous domain. Background Tissue injury in Goodpasture (GP) syndrome (rapidly progressive glomerular nephritis and
Autor:
Billy G. Hudson, Yoshikazu Sado, Yoshifumi Ninomiya, Fernando Ballester, Milton E. Noelken, Sripad Gunwar
Publikováno v:
Journal of Biological Chemistry. 273:8767-8775
Glomerular basement membrane (GBM) plays a crucial function in the ultrafiltration of blood plasma by the kidney. This function is impaired in Alport syndrome, a hereditary disorder that is caused by mutations in the gene encoding type IV collagen, b
Autor:
Jörgen Wieslander, Sripad Gunwar, Billy G. Hudson, Raghuram Kalluri, Charlott Brunmark, Jing Zhou, Tesfamichael Z. Kahsai, George C. Enders, Milton E. Noelken
Publikováno v:
Journal of Biological Chemistry. 272:17023-17032
Seminiferous tubule basement membrane (STBM) plays an important role in spermatogenesis. In the present study, the composition and structural organization of type IV collagen of bovine STBM was investigated. STBM was found to be composed of all six a
Autor:
Mukut Sharma, Virginia J. Savin, Bradley A. Warady, Mary Artero, Helen B. Lovell, Flavio Vincenti, Sripad Gunwar, Ram Sharma, Ellen T. McCarthy, Arnold M. Chonko, Suzanne K. Swan, Eileen N. Ellis
Publikováno v:
New England Journal of Medicine. 334:878-883
Heavy proteinuria and progressive renal injury recur after transplantation in up to 40 percent of patients with renal failure caused by idiopathic focal segmental glomerulosclerosis. A circulating factor may be responsible for this recurrence.To dete
Publikováno v:
Europe PubMed Central
To determine the chain composition of type IV collagen of bovine thoracic aorta, we analyzed collagenase-solubilized carboxyl-terminal noncollagenous (NC1)-domains by high-pressure liquid chromatography, two-dimensional electrophoresis, immunoblottin
Autor:
Sripad Gunwar, Eric G. Neilson, Raghuram Kalluri, Stephen T. Reeders, Jeanne C. Myers, Theodore M. Danoff, Mariko Mariyama, Mae Jane Sun, Billy G. Hudson
Publikováno v:
Journal of Biological Chemistry. 268:8402-8405
Type IV collagen has recently emerged as a family composed of five known chains (alpha 1-alpha 5), each of which contains a carboxyl-terminal noncollagenous domain (NC1) of approximately 230 amino acids. The NC1 domain of the alpha 3(IV) chain is the