Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Srinivasulu Yerukala Sathipati"'
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Background: Glioblastoma (GBM) prognosis remains extremely poor despite standard treatment that includes temozolomide (TMZ) chemotherapy. To discover new GBM drug targets and biomarkers, genes signatures associated with survival and TMZ resistance in
Externí odkaz:
https://doaj.org/article/e17dd8c0964443dd8aeeae79f56a6283
Publikováno v:
HGG Advances, Vol 4, Iss 3, Pp 100190- (2023)
Summary: The ability to detect cancer at an early stage in patients who would benefit from effective therapy is a key factor in increasing survivability. This work proposes an evolutionary supervised learning method called CancerSig to identify cance
Externí odkaz:
https://doaj.org/article/219e64a255fa491d807bdb8a71f2d743
Publikováno v:
Heliyon, Vol 9, Iss 6, Pp e17218- (2023)
Head and neck carcinoma (HNSC) is often diagnosed at advanced stage, incurring poor patient outcome. Despite of advances in chemoradiation and surgery approaches, limited improvements in survival rates of HNSC have been observed over the last decade.
Externí odkaz:
https://doaj.org/article/4db6b3cb9ff241a9a213d825a20bd313
Autor:
Srinivasulu Yerukala Sathipati, Ming-Ju Tsai, Sanjay K. Shukla, Shinn-Ying Ho, Yi Liu, Afshin Behesthi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Bladder urothelial carcinoma (BLC) is one of the most common cancers in men, and its heterogeneity challenges the treatment to cure this disease. Recently, microRNAs (miRNAs) gained promising attention as biomarkers due to their potential ro
Externí odkaz:
https://doaj.org/article/731a5216fde84933882de811b80efc31
Autor:
Srinivasulu Yerukala Sathipati, Ming-Ju Tsai, Tonia Carter, Patrick Allaire, Sanjay K. Shukla, Afshin Beheshti, Shinn-Ying Ho
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 4490-4500 (2022)
Identifying a miRNA signature associated with survival will open a new window for developing miRNA-targeted treatment strategies in stomach and esophageal cancers (STEC). Here, using data from The Cancer Genome Atlas on 516 patients with STEC, we dev
Externí odkaz:
https://doaj.org/article/d619dd079c6b41da8b0db7dd4a7210a2
Publikováno v:
STAR Protocols, Vol 3, Iss 3, Pp 101460- (2022)
Summary: We describe a protocol to identify physicochemical properties using amino acid sequences of spike (S) proteins of SARS-CoV-2. We present an S protein prediction technique named SPIKES, incorporating an inheritable bi-objective combinatorial
Externí odkaz:
https://doaj.org/article/2675333e90f94f61a7f9e2b0637b47e5
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103560- (2022)
Summary: Knowledge of the host-specific properties of the spike protein is of crucial importance to understand the adaptability of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) to infect multiple species and alter transmissibility, par
Externí odkaz:
https://doaj.org/article/b78e450b3ca6426b8179bfb4aabc4cc6
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Autism spectrum disorder (ASD) refers to a wide spectrum of neurodevelopmental disorders that emerge during infancy and continue throughout a lifespan. Although substantial efforts have been made to develop therapeutic approaches, core symptoms persi
Externí odkaz:
https://doaj.org/article/20e4e66e103e4cfd884a2875611cd5d9
Autor:
Srinivasulu Yerukala Sathipati, Ming‑Ju Tsai, Sanjay K. Shukla, Shinn‑Ying Ho, Yi Liu, Afshin Beheshti
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/35fac73855bb46d2b043a52cd8ea5bb1
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Lung adenocarcinoma is a multifactorial disease. MicroRNA (miRNA) expression profiles are extensively used for discovering potential theranostic biomarkers of lung cancer. This work proposes an optimized support vector regression (SVR) metho
Externí odkaz:
https://doaj.org/article/071f0e818b704eceb31f311cc2d18612