Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Srinivasarao Meneni"'
Autor:
Roman Dembinski, Deepthi Khanduri, Adam Sniady, Michael D. Sevilla, Tadeusz Lis, John M. Finke, Srinivasarao Meneni, Sławomir Szafert
Publikováno v:
Chemistry - A European Journal. 15:7569-7577
Sonogashira coupling of diacetyl 5-ethynyl-2′-deoxyuridine with diacetyl 5-iodo-2′-deoxyuridine gave the acylated ethynediyl-linked 2′-deoxyuridine dimer (3 b; 63 %), which was deprotected with ammonia/methanol to give ethynediyl-linked 2′-de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::936c7fa121ccd1bdbca1d19421750c81
https://doi.org/10.1002/chem.200900481
https://doi.org/10.1002/chem.200900481
Publikováno v:
Nucleic Acids Research
When positioned opposite to a dA in a DNA duplex, the prototype arylamine–DNA adduct [N-(2′-deoxyguanosin-yl)-7-fluoro-2-aminofluorene (FAF)] adopts the so-called ‘wedge’ (W) conformation, in which the carcinogen resides in the minor groove o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85a0e8e509ed9548b434a40255044041
https://doi.org/10.1093/nar/gkn1063
https://doi.org/10.1093/nar/gkn1063
Autor:
Craig D. Sergeant, Roman Dembinski, Arnold L. Rheingold, Ronald Gust, Adam Sniady, Srinivasarao Meneni, Ingo Ott
Publikováno v:
Org. Biomol. Chem.. 6:73-80
Reactions of 5-alkynyl-2'-deoxyuridines with dicobalt octacarbonyl Co2(CO)8 in THF at room temperature gave hexacarbonyl dicobalt nucleoside complexes (77-93%). The metallo-nucleosides were characterized, including an X-ray structure of a 1-cyclohexa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::472e7493df5d48662684fc3e4d4eba86
https://doi.org/10.1039/b713371e
https://doi.org/10.1039/b713371e
Autor:
M. Paul Chiarelli, Wang Lee, Lan Gao, Steven M. Shell, Yue Zou, Srinivasarao Meneni, Jiri Sponer, Petr Jurečka, Bongsup P. Cho
Publikováno v:
Biochemistry. 46:11263-11278
A systematic spectroscopic and computational study was conducted in order to probe the influence of base sequences on stacked (S) versus B-type (B) conformational heterogeneity induced by the major dG adduct derived from the model carcinogen 7-fluoro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b62a7520aef9f4ca3a951901c0f0697f
https://doi.org/10.1021/bi700858s
https://doi.org/10.1021/bi700858s
Publikováno v:
Chemical Research in Toxicology. 20:6-10
We report a systematic and quantitative structure-function relationship study of the major N-[deoxyguanosin-8-yl]-2-aminofluorene adduct (AF) derived from the prototype carcinogen 2-aminofluorene and its derivatives. The AF adduct is known to exist i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::202999db5ec797d273a4133be9abc9e5
https://doi.org/10.1021/tx600273h
https://doi.org/10.1021/tx600273h
Publikováno v:
Chemical Research in Toxicology. 19:1040-1043
We report novel induced circular dichroism (ICD) characteristics for probing the conformational heterogeneity induced by the arylamine carcinogen 2-aminofluorene, namely, B type (B), stacked (S), and wedged (W) conformers. CD experiments were conduct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b762e394721e638a31872b0cefbd7bc
https://doi.org/10.1021/tx0601253
https://doi.org/10.1021/tx0601253
The NarI recognition sequence (5'-G1G2CG3CN-3') is the most vulnerable hot spot for frameshift mutagenesis induced by the carcinogen 2-aminofluorene and its analogues in Escherichia coli. Lesioning of the guanine in the G3 position induces an especia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::584a64469c6395759aba4ed5b081c55c
https://europepmc.org/articles/PMC3409668/
https://europepmc.org/articles/PMC3409668/
Publikováno v:
ChemInform. 38
Starting with 5-iodo-2'-deoxyuridine, a series of 5-alkynyl-2'-deoxyuridines (with n-propyl, cyclopropyl, 1-hydroxycyclohexyl, p-tolyl, p-tert-butylphenyl, p-pentylphenyl, and trimethylsilyl alkyne substituents) have been synthesized via the palladiu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f4ffeb7ac051ebb96eb70e7ac3d1c0
https://doi.org/10.1002/chin.200732207
https://doi.org/10.1002/chin.200732207
Publikováno v:
Journal of molecular biology. 366(5)
Adduct-induced conformational heterogeneity complicates the understanding of how DNA adducts exert mutation. A case in point is the N -deacetylated AF lesion [ N -(2′-deoxyguanosin-8-yl)-2-aminofluorene], the major adduct derived from the strong li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b70a07bb23cfeb91fbd9b50294f19599
https://pubmed.ncbi.nlm.nih.gov/17217958
https://pubmed.ncbi.nlm.nih.gov/17217958
Publikováno v:
Journal of Molecular Biology. 398:786
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6373aadf2425dee931ec617f1be094d
https://doi.org/10.1016/j.jmb.2010.03.052
https://doi.org/10.1016/j.jmb.2010.03.052