Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Srinivasan Kandasamy"'
Autor:
Sreenidhi Srinivasan, Saraswathi Subramanian, Sai Shankar Balakrishnan, Kathiravan Ramaiyan Selvaraju, Vandana Manomohan, Suganya Selladurai, Monika Jothivelu, Srinivasan Kandasamy, Dhinakar Raj Gopal, Kumanan Kathaperumal, Andrew J. K. Conlan, Maroudam Veerasami, Douwe Bakker, Martin Vordermeier, Vivek Kapur
Publikováno v:
Frontiers in Veterinary Science, Vol 7 (2020)
In most low- and middle-income countries (LMICs), bovine tuberculosis (bTB) remains endemic due to the absence of control programs. This is because successful bTB control and eradication programs have relied on test-and-slaughter strategies that are
Externí odkaz:
https://doaj.org/article/6375b397c650471eb8af83e82846cca8
Akademický článek
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Publikováno v:
Tuberculosis (Edinburgh, Scotland). 123
Serine/Threonine Protein Kinases (STPKs) phosphorylates target proteins thereby regulates various important cellular signal transduction pathways such as cell division and cell wall synthesis. It has been demonstrated that the STPKs regulate peptidog
Autor:
Thomas P. Stratton, Patricia Soteropoulos, Joel S. Freundlich, Xin Wang, Hsin Pin Ho, Srinivasan Kandasamy, Seema Hussain, Alejandro Davila-Pagan, Ravindra Jadhav, Daigo Inoyama, Nisha Mittal, Eric Singleton, Sean Ekins, Véronique Dartois, Richard Pottorf, Yong Mo Ahn, Pradeep Kumar, Riccardo Russo, Joseph A. Bilotta, Matthew D. Zimmerman, Courtney Grady, Nancy D. Connell, Thomas J. Kim, Steve D. Paget, Steven Park, Shao-Gang Li
Publikováno v:
Cell Chem Biol
Summary The triazine antitubercular JSF-2019 was of interest due to its in vitro efficacy and the nitro group shared with the clinically relevant delamanid and pretomanid. JSF-2019 undergoes activation requiring F420H2 and one or more nitroreductases
Autor:
Joel S. Freundlich, Steven D. Paget, Alexander L. Perryman, Matthew D. Zimmerman, Véronique Dartois, Hsin Pin Ho, Pradeep Kumar, Srinivasan Kandasamy, Eric Singleton, Margareta Tuckman, James L. Occi, Riccardo Russo, Daigo Inoyama, Nancy D. Connell
Mycobacterium tuberculosis infection is responsible for a global pandemic. New drugs are needed that do not show cross-resistance with the existing front-line therapeutics. A triazine antitubercular hit led to the design of a related pyrimidine famil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8093d65a0cf2d1552612dd2923f9b192
https://europepmc.org/articles/PMC5826157/
https://europepmc.org/articles/PMC5826157/
Akademický článek
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Autor:
Srinivasan Kandasamy, Monica Tadi, John Rudrapogu, Govind Biju, Chaitanya Boddikura, Anil Naralasetty
Publikováno v:
International Journal of Research in Medical Sciences. :2126-2128
Ca 125 is used as a diagnostic and prognostic biomarker for ovarian cancer. The level of CA 125 is also elevated in benign conditions like Budd Chiari syndrome, liver cirrhosis and heart failure. But very high level of CA 125 is rarely associated wit
Autor:
Monica E. Florence Tadi, Anil Kumar Naralasetty, Srinivasan Kandasamy, Chaitanya Boddikura, Govind Biju, John Satish Rudrapogu
Publikováno v:
International Journal of Research in Medical Sciences. :2123-2125
This case report describes a patient admitted with shortness of breath of 15 days duration and found to have cardiac tamponade, which masked concomitant pulmonary embolism that was diagnosed by echocardiographic signs of dilate RA/RV with PAH only af
Publikováno v:
Microbiological research. 170
Serine/threonine protein kinases play a major role in peptidoglycan biosynthesis in Mycobacterium tuberculosis. To explore the mechanism in detail, in the present study, we have constructed a double knockout (DKO) strain lacking pknI and dacB2 in M.
Publikováno v:
BMC Infectious Diseases
Background Mycobacterium tuberculosis is a slow growing infectious pathogen. It takes twenty hours for a single cell to divide into two. Its cell division is complex involving a number of proteins. Although, the physiological roles of several serine/