Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Srinivasa Rao Bandi"'
Autor:
Jing Zhang, Olesya Vakhrusheva, Srinivasa Rao Bandi, Özlem Demirel, Julhash U. Kazi, Ramona Gomes Fernandes, Katja Jakobi, Astrid Eichler, Lars Rönnstrand, Michael A. Rieger, Nick Carpino, Hubert Serve, Christian H. Brandts
Publikováno v:
Stem Cell Reports, Vol 5, Iss 4, Pp 633-646 (2015)
FLT3 and c-KIT are crucial regulators of hematopoietic stem and progenitor cells. We investigated the role of STS1 and STS2 on FLT3 and c-KIT phosphorylation, activity, and function in normal and stress-induced hematopoiesis. STS1/STS2-deficient mice
Externí odkaz:
https://doaj.org/article/6ffbb32c40b742d3a8f0c59da61e2f0e
Autor:
Elise Gunzburger, Timothy Wright, Edward N. Janoff, Harsh Pratap, John Kittelson, Lindsay K. Nicholson, Edward M. Gardner, Srinivasa Rao Bandi, Elisabeth Bowers, Brent E. Palmer
Publikováno v:
Immunobiology. 223:839-849
Identifying HIV-1-associated B cell defects and responses to activation may direct interventions to circumvent their impaired antibody responses to infection and vaccines. Among 34 viremic HIV-1-infected and 20 seronegative control adults, we measure
Autor:
Peter Brams, Robert C. Edgar, Srinivasa Rao Bandi, Rena A. Mizrahi, Jackson Leong, David S. Johnson, Matthew J. Spindler, Adam S. Adler, Michael A. Asensio, Pallavi Tawde, Renee Leong, Daniel Bedinger, Haichun Huang, Matthew Adams
Publikováno v:
mAbs
Deep sequencing and single-chain variable fragment (scFv) yeast display methods are becoming more popular for discovery of therapeutic antibody candidates in mouse B cell repertoires. In this study, we compare a deep sequencing and scFv display metho
Autor:
Kyoko Hayakawa, Srinivasa Rao Bandi, Anthony M. Formica, Richard R. Hardy, Yue-Sheng Li, Susan A. Shinton, Joni Brill-Dashoff
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology
Frontiers in Immunology
The Lin28b+Let7- axis in fetal/neonatal development plays a role in promoting CD5+ B1a cell generation as a B-1 B cell developmental outcome. Here we identify the Let7 target, Arid3a, as a crucial molecular effector of the B-1 cell developmental prog
Autor:
Srinivasa Rao Bandi, Katja Jakobi, Nick Carpino, Ramona Gomes Fernandes, Jing Zhang, Olesya Vakhrusheva, Hubert Serve, Özlem Demirel, Lars Rönnstrand, Michael A. Rieger, Julhash U. Kazi, Christian Brandts, Astrid Eichler
Publikováno v:
Stem Cell Reports, Vol 5, Iss 4, Pp 633-646 (2015)
Stem Cell Reports
Stem Cell Reports
Summary FLT3 and c-KIT are crucial regulators of hematopoietic stem and progenitor cells. We investigated the role of STS1 and STS2 on FLT3 and c-KIT phosphorylation, activity, and function in normal and stress-induced hematopoiesis. STS1/STS2-defici
Autor:
Srinivasa Rao Bandi, Susan A. Shinton, Richard R. Hardy, Lingjuan Tang, Yue-Sheng Li, Yan Zhou, Kyoko Hayakawa
Publikováno v:
The Journal of Experimental Medicine
Zhou et al. demonstrate a requirement for the Let-7–Lin28b axis regulating a shift in development between fetal liver and bone marrow B lymphocyte progenitors in the generation of B1 versus B2 B cells. Specifically, the transcription factor Arid3a,
Autor:
Thirumala-Devi Kanneganti, Gordon R. Johnson, Peter Vogel, Srinivasa Rao Bandi, John R. Lukens, Daniel J. McGoldrick, Prajwal Gurung, Christopher Calabrese, Robert A. Carter, Lieselotte Vande Walle, Mohamed Lamkanfi
Publikováno v:
Nature
Pstpip2-mutant mice fed a high-fat diet are protected against inflammatory bone disease and bone erosion; this protection is associated with reductions in intestinal Prevotella levels and pro-IL-1β expression, and is dependent on the deletion of bot
Autor:
Srinivasa Rao, Bandi, Christian, Brandts, Marion, Rensinghoff, Rebekka, Grundler, Lara, Tickenbrock, Gabriele, Köhler, Justus, Duyster, Wolfgang E, Berdel, Carsten, Müller-Tidow, Hubert, Serve, Bülent, Sargin, Martin, Wolf
Publikováno v:
Blood. 114(19)
Somatic mutations of Kit have been found in leukemias and gastrointestinal stromal tumors. The proto-oncogene c-Cbl negatively regulates Kit and Flt3 by its E3 ligase activity and acts as a scaffold. We recently identified the first c-Cbl mutation in
Autor:
Carsten Müller-Tidow, Chunaram Choudhary, Ivan Dikic, Bülent Sargin, Benjamin August, Mirko H. H. Schmidt, Hubert Serve, Lara Tickenbrock, Joachim Schwäble, Rebekka Grundler, Marion Rensinghoff, Wolfgang E. Berdel, Srinivasa Rao Bandi, Christine Thiessen, Christian Brandts, Justus Duyster, Steffen Koschmieder, Nicola Crosetto
Publikováno v:
Blood. 110(3)
In acute myeloid leukemia (AML), mutational activation of the receptor tyrosine kinase (RTK) Flt3 is frequently involved in leukemic transformation. However, little is known about a possible role of highly expressed wild-type Flt3 in AML. The proto-o
Autor:
Lara Tickenbrock, Marion Rensinghoff, Carsten Müller-Tidow, Rebekka Grundler, Wolfgang E. Berdel, Justus Duyster, Srinivasa Rao Bandi, Hubert Serve, Christian Brandts
Publikováno v:
Blood. 114:3970-3970
Abstract 3970 Poster Board III-906 Purpose The Cbl proto-oncogene products have emerged as important components of the signal transduction cascades downstream of both non-receptor and receptor tyrosine kinases (RTKs). By regulation of receptor traffi