Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Srinivasa R. Ramisetti"'
Autor:
Charyguly Annageldiyev, Su-Fern Tan, Shreya Thakur, Pavan Kumar Dhanyamraju, Srinivasa R. Ramisetti, Preeti Bhadauria, Jacob Schick, Zheng Zeng, Varun Sharma, Wendy Dunton, Sinisa Dovat, Dhimant Desai, Hong Zheng, David J. Feith, Thomas P. Loughran, Shantu Amin, Arun K. Sharma, David Claxton, Arati Sharma
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Acute myeloid leukemia is a heterogeneous disease with a 5-year survival rate of 28.3%, and current treatment options constrained by dose-limiting toxicities. One of the key signaling pathways known to be frequently activated and dysregulated in AML
Externí odkaz:
https://doaj.org/article/91cfc78f3e9d4b93afe1dfa050439f7e
Autor:
Chendil Damodaran, Arun K. Sharma, Nikolay V. Dokholyan, Venkat R. Chirasani, Srinivasa R. Ramisetti, Murali K. Ankem, Cibi A. Sripathi, Becca V. Baby, Venkatesh Kolluru, Balaji Chandrasekaran, Ashish Tyagi
Supplementary Files
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd17fe8a233929b58764f877b0544c7
https://doi.org/10.1158/1535-7163.22519455.v1
https://doi.org/10.1158/1535-7163.22519455.v1
Autor:
Madhu Babu Battu, Srinivasa R. Ramisetti, Raghavendra Gowda, Yu Chi Chen, Xinghai Xia, Tom Kirchhausen, Susan Hafenstein, Qilong Feng, Pingnian He, Venkat R. Chirasani, Nikolay V. Dokholyan, Kyle B. LaPenna, Shantu Amin, Sung Hyun Cho, Gavin P. Robertson, Arthur Berg, Saketh S. Dinavahi, Arun Sharma
Publikováno v:
Cancer Lett
Targeting the metastatic process to prevent disease dissemination in cancer remains challenging. One step in the metastatic cascade involves cancer cells transiting through the vascular endothelium after inflammation has increased the permeability of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99301da5333fbc38c15c1214727fc789
https://doi.org/10.1016/j.canlet.2021.01.004
https://doi.org/10.1016/j.canlet.2021.01.004
Autor:
Ashish Tyagi, Becca V. Baby, Venkat R. Chirasani, Cibi A. Sripathi, Chendil Damodaran, Murali K. Ankem, Arun Sharma, Venkatesh Kolluru, Balaji Chandrasekaran, Nikolay V. Dokholyan, Srinivasa R. Ramisetti
Publikováno v:
Molecular Cancer Therapeutics. 19:2422-2431
Notch1 activation triggers significant oncogenic signaling that manifests as enhanced metastatic potential and tumorigenesis in colorectal cancer. Novel small-molecule inhibitors, mainly plant-derived analogs, have low toxicity profiles and higher bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb2389b2bdaad383725135e10511c315
https://doi.org/10.1158/1535-7163.mct-19-0949
https://doi.org/10.1158/1535-7163.mct-19-0949
Autor:
Srinivasa R. Ramisetti, Parvesh Singh, Shantu Amin, Arun Sharma, Brian K. Law, Ashona Singh-Pillay, Aruna S. Jaiswal, Satya Narayan
Publikováno v:
European Journal of Medicinal Chemistry
Despite new agent development and short-term benefits in patients with colorectal cancer (CRC), metastatic CRC cure rates have not improved due to high rates of 5-fluorouracil (5-FU)/leucovorin/oxaliplatin (FOLFOX)-resistance and a clinical therapeut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07b41a78bae6fd4f847416c955f8e934
https://doi.org/10.1016/j.ejmech.2018.10.052
https://doi.org/10.1016/j.ejmech.2018.10.052
Autor:
Satya Narayan, Srinivasa R. Ramisetti, Shantu Amin, Manoj K. Pandey, Deepkamal N. Karelia, Sang Y. Lee, Arun Sharma
Publikováno v:
European Journal of Medicinal Chemistry. 143:1919-1930
A series of novel thio- and seleno-barbituric acid derivatives were synthesized by varying the substituents at N1 and N3 (ethyl, methyl, allyl, and phenyl), and C5 tethered with dienyl and trienyl moieties attached to substituents such as phenyl, 2-f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ca6b0051ef7537ec6cc27f1c1c25d19
https://doi.org/10.1016/j.ejmech.2017.11.006
https://doi.org/10.1016/j.ejmech.2017.11.006
Publikováno v:
Polycyclic Aromatic Compounds. 40:88-98
An efficient synthesis of potentially carcinogenic dibenzo[a,l]tetracene 1 and dibenzo[a,j]tetracene 2 has been developed and the synthetic standards were used to establish their environmental presence. The synthesis involves Diels–Alder reaction o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1fae7f5994e58abeb5f55e9fa773f66
https://doi.org/10.1080/10406638.2017.1362013
https://doi.org/10.1080/10406638.2017.1362013
Autor:
Ashish, Tyagi, Balaji, Chandrasekaran, Venkatesh, Kolluru, Becca V, Baby, Cibi A, Sripathi, Murali K, Ankem, Srinivasa R, Ramisetti, Venkat R, Chirasani, Nikolay V, Dokholyan, Arun K, Sharma, Chendil, Damodaran
Publikováno v:
Molecular cancer therapeutics. 19(12)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3f3b7de396a909203dbeb8e2c78aea56
https://pubmed.ncbi.nlm.nih.gov/33087513
https://pubmed.ncbi.nlm.nih.gov/33087513
Autor:
Parvesh Singh, Srinivasa R. Ramisetti, Shantu Amin, Arun Sharma, A. S. Prakasha Gowda, Manoj K. Pandey, Ugir Hossain Sk, Deepkamal N. Karelia
Publikováno v:
European journal of medicinal chemistry. 135
Synthesis and anti-melanoma activity of novel naphthalimide isoselenocyanate (NISC) and naphthalimide selenourea (NSU) analogs are described. The novel agents were screened for growth inhibition of different human melanoma cell lines including those
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73059bb3288a6a43c18c2c7774d3e983
https://pubmed.ncbi.nlm.nih.gov/28458134
https://pubmed.ncbi.nlm.nih.gov/28458134
Autor:
Arun Sharma, Trupti Patel, Arati Sharma, Saumya Iyer, Shantu Amiin, David F. Claxton, Shreya Thakur, Srinivasa R. Ramisetti, Pavan Kumar Dhanyamraju, Charyguly Annageldiyev
Publikováno v:
Cancer Research. 79:358-358
Acute myeloid leukemia (AML) is a heterogeneous disease with percent remission of 35-40% for younger patients and 5-15% for older patients and a survival of 5-10 months if left untreated. This emphasizes the urgent unmet need for new therapeutics in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d91bea2c588cfde5c0478f2a1a3c84f2
https://doi.org/10.1158/1538-7445.am2019-358
https://doi.org/10.1158/1538-7445.am2019-358