Maternal serum biomarkers for risk assessment in gestational diabetes. A potential universal screening test to predict GDM status

Autor: Srinivasa R Nagalla, Caryn K Snyder, John E Michaels, Mary J Laughlin, Charles T Roberts, Madhuri Balaji, V Balaji, V Seshiah, Paturi V Rao

Publikováno v: Indian Journal of Endocrinology and Metabolism, Vol 19, Iss 1, Pp 155-159 (2015)

The prevalence of gestational diabetes mellitus (GDM) is increasing because of the worldwide obesity/diabetes epidemic. The complications of untreated GDM affect both the mother and baby and include complications during pregnancy as well as increased

Externí odkaz: https://doaj.org/article/abd06b98de0d4789bed9c079210b28d3

Rapid Point-of-Care Test for Determination of C-Peptide Levels

Autor: Charles Roberts, Srinivasa R. Nagalla, Siting Chen, Steven C. Kazmierczak, Eric S. Bean, Dhanalakshmi Nair-Schaef, Paturi V. Rao

Publikováno v: J Diabetes Sci Technol

C-peptide is co-secreted with insulin and is not subject to hepatic clearance and thus reflects functional β-cell mass. Assessment of C-peptide levels can identify individuals at risk for or with type 1 diabetes with residual β-cell function in who

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75e91b252a90d0043414af488efd8a15
https://europepmc.org/articles/PMC9264426/

Maternal serum glycosylated fibronectin as a short-term predictor of preeclampsia: a prospective cohort study

Autor: Charles T. Roberts, Soeren Lange, Begoña Martinez de Tejada, I Hoffmann, Evelyn A. Huhn, Michael Gravett, Olav Lapaire, Srinivasa R. Nagalla, Kylie M. Sage

Publikováno v: BMC Pregnancy and Childbirth, Vol. 20, No 1 (2020) P. 128
BMC Pregnancy and Childbirth
BMC Pregnancy and Childbirth, Vol 20, Iss 1, Pp 1-8 (2020)

Background Preeclampsia is a major pregnancy complication that results in significant maternal and infant mortality, most of which occurs in low and middle-income countries. The accurate and timely diagnosis of preeclampsia is critical in management

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a67da7e73e24e6d1a19a8b0ae3dc08e
https://doi.org/10.1186/s12884-020-2809-2

Proteomic analysis of cervical vaginal fluid proteins among women in recurrent preterm labor

Autor: Srinivasa R. Nagalla, Amanda Kinhnarath, Monica Rincon, Michael G. Gravett, Jamie O. Lo, Ashok P. Reddy, Leonardo Pereira, Victoria H. J. Roberts, Janice Snyder, Phillip A. Wilmarth

Publikováno v: The Journal of Maternal-Fetal & Neonatal Medicine. 27:1183-1188

Proteomic analysis of four cervical-vaginal fluid (CVF) proteins to identify biomarkers of recurrent preterm birth (rPTB) in at-risk women prior to onset of preterm labor.Nested case control study from 2007 to 2011 of women with prior spontaneous pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b427c57e99e98287cc8640aca8e8c69
https://doi.org/10.3109/14767058.2013.852172

Quantification of Isotopically Overlapping Deamidated and 18O-Labeled Peptides Using Isotopic Envelope Mixture Modeling

Autor: Srinivasa R. Nagalla, Lucinda J. G. Robertson, Surendra Dasari, Ashok P. Reddy, Phillip A. Wilmarth, Larry L. David

Publikováno v: Journal of Proteome Research. 8:1263-1270

A robust peptide quantification method was developed where overlapping peptide isotopic distributions were fit with predicted peptide isotopic envelope mixture models (IEMMs). Application to two difficult quantitative problems was demonstrated. The f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef404e8489af474414bbcd2ba9fb4394
https://doi.org/10.1021/pr801054w