Výsledky vyhledávání - "Srinivas V, Ramaswamy"

Can mycobacterial katG genetic changes in isoniazid-resistant tuberculosis influence human disease features?

Autor: Brenda E. Jones, Patricio Escalante, Larry D. Teeter, Edward A. Graviss, Srinivas V. Ramaswamy, Roberta McKean-Cowdin, Natalie Williams-Bouyer

Publikováno v: The International Journal of Tuberculosis and Lung Disease. 17:644-651

BACKGROUND Isoniazid-resistant (INHr) Mycobacterium tuberculosis isolates often have katG mutations, and katG is a virulence factor in animal models. It is unclear if katG mutations or other mutations influence the characteristics of human disease. O

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::64fa91575492a7e169934a242e2e0b0b
https://doi.org/10.5588/ijtld.12.0380

Zobrazit plný text záznamu

Detection by Denaturing Gradient Gel Electrophoresis of pncA Mutations Associated with Pyrazinamide Resistance in Mycobacterium tuberculosis Isolates from the United States-Mexico Border Region

Autor: Srinivas V. Ramaswamy, Edward A. Graviss, Ishmael I. Rosas, Mark T. McCammon, John S. Gillette, Jan Vijg, Teresa N. Quitugua, Derek P. Thomas

Publikováno v: Antimicrobial Agents and Chemotherapy. 49:2210-2217

Denaturing gradient gel electrophoresis (DGGE) was used to probe for mutations associated with pyrazinamide (PZA) resistance in the pncA gene of Mycobacterium tuberculosis . DGGE scans for mutations across large regions of DNA and rivals sequencing i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beddc3e186e64905b03cf6af0b1a77b2
https://doi.org/10.1128/aac.49.6.2210-2217.2005

Zobrazit plný text záznamu

spa Typing Method for Discriminating among Staphylococcus aureus Isolates: Implications for Use of a Single Marker To Detect Genetic Micro- and Macrovariation

Autor: James M. Musser, Edward A. Graviss, Srinivas V. Ramaswamy, Barry N. Kreiswirth, Larry Koreen, Steven Naidich

Publikováno v: Journal of Clinical Microbiology. 42:792-799

Strain typing of microbial pathogens has two major aims: (i) to index genetic microvariation for use in outbreak investigations and (ii) to index genetic macrovariation for use in phylogenetic and population-based analyses. Until now, there has been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4557a6e07fb9c07cd3d24c132dea35b
https://doi.org/10.1128/jcm.42.2.792-799.2004

Zobrazit plný text záznamu

Negligible Genetic Diversity of Mycobacterium tuberculosis Host Immune System Protein Targets: Evidence of Limited Selective Pressure

Autor: Amol Amin, Srinivas V. Ramaswamy, James M. Musser

Publikováno v: Genetics. 155:7-16

A common theme in medical microbiology is that the amount of amino acid sequence variation in proteins that are targets of the host immune system greatly exceeds that found in metabolic enzymes or other housekeeping proteins. Twenty-four Mycobacteriu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67ec4b2363edbdc744ece2fc5560d444
https://doi.org/10.1093/genetics/155.1.7

Zobrazit plný text záznamu

Inhibition of a Mycobacterium tuberculosis β-Ketoacyl ACP Synthase by Isoniazid

Autor: David A. Mead, Ya Qi Zhu, Richard A. Slayden, Srinivas V. Ramaswamy, James M. Musser, Deborah D. Crane, Xi Pan, Clifton E. Barry, Khisimuzi Mdluli

Publikováno v: Science. 280:1607-1610

Although isoniazid (isonicotinic acid hydrazide, INH) is widely used for the treatment of tuberculosis, its molecular target has remained elusive. In response to INH treatment, saturated hexacosanoic acid (C26:0) accumulated on a 12-kilodalton acyl c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da2238302fb365689e9c5e325bac485c
https://doi.org/10.1126/science.280.5369.1607

Zobrazit plný text záznamu

Molecular characterization of Mycobacterium tuberculosis isolates from Izmir, Turkey

Autor: Can, Bicmen, Nuran, Esen, Edward A, Graviss, Natalie, Williams-Bouyer, Srinivas V, Ramaswamy, Nuran, Yulug

Publikováno v: The new microbiologica. 30(3)

In recent years, molecular typing methods have been used in epidemiologic studies of Mycobacterium tuberculosis isolates in various areas of the world. However, there have been few data on this issue in Turkey. We describe the molecular characterizat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2e5107330d98cdba8c7cfc3e3169a144
https://pubmed.ncbi.nlm.nih.gov/17802900

Zobrazit plný text záznamu

Molecular characterization of nontypeable group B streptococcus

Autor: Patricia Ferrieri, Aurea E. Flores, Lawrence C. Paoletti, Srinivas V. Ramaswamy

Publikováno v: Journal of clinical microbiology. 44(7)

Traditionally, the capsular polysaccharide (CPS) antigen has been used to distinguish between the nine known serotypes of group B streptococcus (GBS) by classical antibody-antigen reactions. In this study, we used PCR for all CPSs and selected protei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79519773c869c8b80dfa20ea29ba5222
https://pubmed.ncbi.nlm.nih.gov/16825355

Zobrazit plný text záznamu

Identification of novel cps locus polymorphisms in nontypable group B Streptococcus

Autor: Lawrence C. Paoletti, Aurea E. Flores, Nikhil Kumar, Patricia Ferrieri, Srinivas V. Ramaswamy, Hervé Tettelin, Lawrence C. Madoff

Publikováno v: Journal of medical microbiology. 55(Pt 6)

Group B Streptococcus (GBS) is an important pathogen responsible for a variety of diseases in newborns and the elderly. A clinical GBS isolate is considered nontypable (NT) when serological methods fail to identify it as one of nine known GBS serotyp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53688e347618aa0c32d09495fab03113
https://pubmed.ncbi.nlm.nih.gov/16687599

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání