Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Srinivas Suda"'
Autor:
Justine Meiller, Martin Clynes, Paula Meleady, Srinivas Suda, Michael Henry, Markus Riedl, Orla Coleman, Niall Barron
Publikováno v:
Journal of Proteomics. 195:23-32
Cell line engineering using microRNAs represents a desirable route for improving the efficiency of recombinant protein production by CHO cells. In this study we generated stable CHO DP12 cells expressing a miR-7 sponge transcript which sequesters miR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c60574234af48d1043d2993af03665
https://doi.org/10.1016/j.jprot.2019.01.003
https://doi.org/10.1016/j.jprot.2019.01.003
Autor:
Padraig Doolan, Antonio Alarcon Miguez, Joanne Keenan, Srinivas Suda, Martin Clynes, Berta Capella Roca, Niall Barron, Donal J. O’Gorman
Publikováno v:
Cytotechnology
In order to study the impact of zinc and copper on the titer levels of mAb and recombinant protein in CHO cells, the IgG-expressing (DP12) and EPO-expressing (SK15) cell lines were cultured in chemically defined media with increasing concentrations o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::460bceaa612956c4e4dd524c9d2de345
https://pubmed.ncbi.nlm.nih.gov/31396753
https://pubmed.ncbi.nlm.nih.gov/31396753
Autor:
Mitchell D. Knutson, Shu G. Chen, Jerrold R. Turner, Juan Qian, Srinivas Suda, Ajai K. Tripathi, Amber Beserra, Ulrich Hopfer, Swati Haldar, Neena Singh, Michael D. Garrick, Ajay Vir Singh
Publikováno v:
Free Radical Biology and Medicine. 84:322-330
Excess circulating iron is stored in the liver, and requires reduction of non-Tf-bound iron (NTBI) and transferrin (Tf) iron at the plasma membrane and endosomes, respectively, by ferrireductase (FR) proteins for transport across biological membranes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eacb740c5ae6be8584c4844dc9d1690a
https://doi.org/10.1016/j.freeradbiomed.2015.03.037
https://doi.org/10.1016/j.freeradbiomed.2015.03.037
Autor:
Amber Beserra, Ulrich Hopfer, Jerrold R. Turner, Swati Haldar, Neena Singh, Juan Qian, Srinivas Suda, Ajai K. Tripathi, Matthew K. McElwee
Publikováno v:
Journal of Biological Chemistry. 290:5512-5522
Brain iron-dyshomeostasis is an important cause of neurotoxicity in prion disorders, a group of neurodegenerative conditions associated with the conversion of prion protein (PrP(C)) from its normal conformation to an aggregated, PrP-scrapie (PrP(Sc))
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66465303794463c7d5b63b1fefc869aa
https://doi.org/10.1074/jbc.m114.607507
https://doi.org/10.1074/jbc.m114.607507
Autor:
Charumathi Anbalagan, Deepak Sharma, Ajay Vir Singh, Neena Singh, Srinivas Suda, Chinmay K. Mukhopadhyay, Katharine Horback, Som Dev, Ajai K. Tripathi, Swati Haldar, Amber Beserra, Joseph Wong
Publikováno v:
Antioxidants & Redox Signaling. 20:1324-1363
Iron has emerged as a significant cause of neurotoxicity in several neurodegenerative conditions, including Alzheimer's disease (AD), Parkinson's disease (PD), sporadic Creutzfeldt-Jakob disease (sCJD), and others. In some cases, the underlying cause
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d7d7b4104b327986865d0d6ec118305
https://doi.org/10.1089/ars.2012.4931
https://doi.org/10.1089/ars.2012.4931
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1485
Antimicrobial peptides (AMPs) are natural defense compounds which are synthesized as ribosomal gene-encoded pre-peptides and produced by all living organisms. AMPs are small peptides, usually cationic and typically have hydrophobic residues which int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6a23e653e792497aa07c557fd060e32b
https://pubmed.ncbi.nlm.nih.gov/27730566
https://pubmed.ncbi.nlm.nih.gov/27730566
Publikováno v:
Methods in Molecular Biology ISBN: 9781493964109
Antimicrobial peptides (AMPs) are natural defense compounds which are synthesized as ribosomal gene-encoded pre-peptides and produced by all living organisms. AMPs are small peptides, usually cationic and typically have hydrophobic residues which int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d83845e7b40a98e34fa95344364bb8b3
https://doi.org/10.1007/978-1-4939-6412-3_22
https://doi.org/10.1007/978-1-4939-6412-3_22
Publikováno v:
Current Protein & Peptide Science. 13:193-204
The continuing problem of the emergence of multidrug resistance in pathogens has resulted in renewed efforts to identify novel antimicrobials that could be used in clinical settings. Lantibiotics are bacterially produced gene encoded antimicrobial pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec7d4898aa0cde42a3d680767dc7fd77
https://doi.org/10.2174/138920312800785021
https://doi.org/10.2174/138920312800785021
Publikováno v:
Journal of Bacteriology. 194:708-714
Ltnα and Ltnβ are individual components of the two-peptide lantibiotic lacticin 3147 and are unusual in that, although ribosomally synthesized, they contain d -amino acids. These result from the dehydration of l -serine to dehydroalanine by LtnM an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14dd1d4a78e94960e1957cf69eba0198
https://doi.org/10.1128/jb.06185-11
https://doi.org/10.1128/jb.06185-11
Publikováno v:
Chemistry & Biology. 17(10):1151-1160
peer-reviewed Lacticin 3147 is a lantibiotic with seven lanthionine bridges across its two component peptides, Ltnα and Ltnβ. Although it has been proposed that the eponymous lanthionine and (β-methyl)lanthionine (Lan and meLan) bridges present in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a1d02141754aa34a39db2e01bb3302b