Výsledky vyhledávání - "Srinivas Rapireddy"

Akademický článek

Duplex DNA-Invading γ-Modified Peptide Nucleic Acids Enable Rapid Identification of Bloodstream Infections in Whole Blood

Autor: Jörk Nölling, Srinivas Rapireddy, Joel I. Amburg, Elizabeth M. Crawford, Ranjit A. Prakash, Arthur R. Rabson, Yi-Wei Tang, Alon Singer

Publikováno v: mBio, Vol 7, Iss 2 (2016)

ABSTRACT Bloodstream infections are a leading cause of morbidity and mortality. Early and targeted antimicrobial intervention is lifesaving, yet current diagnostic approaches fail to provide actionable information within a clinically viable time fram

Externí odkaz: https://doaj.org/article/b4a649e5ac0344b69438143ced39ea36

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Akademický článek

Effect of Steric Constraint at the γ-Backbone Position on the Conformations and Hybridization Properties of PNAs

Autor: Matthew J. Crawford, Srinivas Rapireddy, Raman Bahal, Iulia Sacui, Danith H. Ly

Publikováno v: Journal of Nucleic Acids, Vol 2011 (2011)

Conformationally preorganized peptide nucleic acids (PNAs) have been synthesized through backbone modifications at the γ-position, where R = alanine, valine, isoleucine, and phenylalanine side chains. The effects of these side-chains on the conforma

Externí odkaz: https://doaj.org/article/4cd5cb9d04ad4c1eb8394000127bedc2

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