Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Srinivas Gangula"'
Autor:
Naveenkumar Kolla, Chandrashekar R. Elati, Pravinchandra J. Vankawala, Srinivas Gangula, Eswaraiah Sajja, Yerremilli Anjaneyulu, Apurba Bhattacharya, Venkataraman Sundaram, Vijayavitthal T. Mathad
Publikováno v:
CHIMIA, Vol 60, Iss 9 (2006)
The development of a large-scale synthesis for (1S)-3-methyl-1-(2-piperidin-1-ylphenyl)butan-1-amine (S-(+)-1), a key intermediate of repaglinide (2), is described. The process conditions for S-(+)-1 involving nucleophilic substitution, Grignard rea
Externí odkaz:
https://doaj.org/article/7a74b464ce584d1d93f5c6f00548117f
Autor:
Kaid C. Harper, En-Xuan Zhang, Zhi-Qing Liu, Timothy Grieme, Timothy B. Towne, Daniel J. Mack, Jeremy Griffin, Song-Yuan Zheng, Ning-Ning Zhang, Srinivas Gangula, Jia-Long Yuan, Robert Miller, Ping-Zhong Huang, James Gage, Moiz Diwan, Yi-Yin Ku
Publikováno v:
Organic Process Research & Development. 26:404-412
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f74da2cd95a23bdf465a17551b81c41a
https://doi.org/10.1021/acs.oprd.1c00436
https://doi.org/10.1021/acs.oprd.1c00436
Autor:
Vilas Hareshwar Dahanukar, Sudharkar Reddy Baddam, Uday Kumar Neelam, Rakeshwar Bandichhor, Srinivas Gangula
Publikováno v:
Organic Process Research & Development. 19:470-475
An investigation into the Kumada cross coupling reaction was conducted by developing a reliable, efficient procedure for the Grignard reagent and its subsequent cross coupling reaction. Safe Mg metal activation as well as a moisture-free system was c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fa9feb173adf0b372d0983c7158ed6c
https://doi.org/10.1021/op500343d
https://doi.org/10.1021/op500343d
Autor:
Narra Santosh Reddy, Medisetti Venkata Rama Krishna, Kushal Surajmal Manudhane, Gunupati Sharathchandra Reddy, Srinivas Gangula, Kopparapu Janardana Sarma Ramachandra
Publikováno v:
Organic Process Research & Development. 17:1272-1276
Synthesis of pharmaceutically active compounds by employing continuous flow micromixing reactor technology is an interesting research area. In this article we describe the synthesis of benzimidazol...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2c46901bbb4b37293c0c3ed2e43604d
https://doi.org/10.1021/op300325f
https://doi.org/10.1021/op300325f
Autor:
Ashok Dongamanti, Chandrasekar Elati, Rakeshwar Bandichhor, Srinivas Gangula, Naveen Kumar Kolla
Publikováno v:
Synthetic Communications. 42:3344-3360
An efficient process for production of paroxetine hydrochloride hemihydrate 1, a selective 5-hydroxytryptamine (serotonin) reuptake inhibitor, is described. Identification and control of potential ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::744d24d4fb80a160c327bf188172d00a
https://doi.org/10.1080/00397911.2011.582216
https://doi.org/10.1080/00397911.2011.582216
Autor:
Srinivas Gangula, Apurba Bhattacharya, Satish Varma Mudunuru, Ashok Dongamanti, Anitha Nardela, Rakeshwar Bandichhor, Chandrashekhar R. Elati
Publikováno v:
Synthetic Communications. 40:2254-2268
Syntheses of all eight enantiomerically pure diastereomers of aprepitant and assignment of absolute configuration at newly generated stereocenters by NMR and x-ray crystallographic analysis were achieved.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa7751deb3fdd5cc07e94af9583cbaad
https://doi.org/10.1080/00397910903221084
https://doi.org/10.1080/00397910903221084
Autor:
Srinivas Gangula, Chandrasekhar Ravi Ram Elati, Uday Kumar Neelam, Rakeshwar Bandichhor, Sudhakar Reddy Baddam, Ashok Dongamanti, Anitha Neredla
Publikováno v:
Organic Process Research & Development. 14:229-233
An improved large-scale synthesis of lansoprazole 1 an anti-ulcer drug is described. The synthesis commences with condensation of 2-mercaptobenzimadazole 3 with 2-chloromethyl-3methyl-4-(2, 2, 2-trifluoro ethoxy) pyridine hydrochloride 2 using water
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::530cc83ec6dcc4538a983c166ec220b6
https://doi.org/10.1021/op900258b
https://doi.org/10.1021/op900258b
Autor:
Chandrashekar R. Elati, Anitha Nardela, Srinivas Gangula, Rakeshwar Bandichhor, D. Ashok, Apurba Bhattacharya
Publikováno v:
Green Chemistry Letters and Reviews. 2:243-247
A protocol for regeneration of key intermediate of aprepitant from its undesired diastereomers is described. This work features the recycling of at least one-third of the undesired isomers (ent-6, 7 and ent-7) to desired isomer 4 as the key early int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ea460b706d313569e38e6192e9b89b3
https://doi.org/10.1080/17518250903400117
https://doi.org/10.1080/17518250903400117
Autor:
S. Ashok, Apurba Bhattacharya, Chandrashekar R. Elati, Srinivas Gangula, Rakeshwarar Bandichhor, Anitha Naredla
Publikováno v:
Synthetic Communications. 38:2950-2957
A simple, new synthesis of fosphenytoin sodium 1, a prodrug, via imidate ester and employing mild reaction conditions is described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32989cc534d075208d6921ebd1edee6c
https://doi.org/10.1080/00397910802005281
https://doi.org/10.1080/00397910802005281
Autor:
Vijayavitthal T. Mathad, Venkatraman Sundaram, Apurba Bhattacharya, Muttu L. Avinigiri, Subrahmanyeswararao Chalamala, Pravinchandra J. Vankawala, Rakeshwar Bandichhor, Naveenkumar Kolla, Anitha Naredla, Chandrashekar R. Elati, Srinivas Gangula
Publikováno v:
Tetrahedron Letters. 48:8001-8004
A simple and convergent approach to enantiomerically pure 5-[[2-[1-[3,5-bis(trifluoromethyl)phenyl]ethoxy-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one 1, a potent orally active antagonist of the human neurokinin-1 (NK-1) r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e83463e2bb6792e4686e56572d6c18b0
https://doi.org/10.1016/j.tetlet.2007.09.051
https://doi.org/10.1016/j.tetlet.2007.09.051