Zobrazeno 1 - 10
of 356
pro vyhledávání: '"Srinivas Aluru"'
Autor:
Haowen Zhang, Li Song, Xiaotao Wang, Haoyu Cheng, Chenfei Wang, Clifford A. Meyer, Tao Liu, Ming Tang, Srinivas Aluru, Feng Yue, X. Shirley Liu, Heng Li
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-6 (2021)
As studies continue sequencing with deeper coverage, computational processing of these profiles has become increasingly resource consuming. Here the authors designed an efficient computational method called Chromap to align and preprocess high throug
Externí odkaz:
https://doaj.org/article/0d8e074a07ed48daaa24e1ce45413134
Autor:
Luis M. Rodriguez-R, Chirag Jain, Roth E. Conrad, Srinivas Aluru, Konstantinos T. Konstantinidis
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
Externí odkaz:
https://doaj.org/article/8efd335ed6214131a12dfcf0d811a4b7
Publikováno v:
BMC Genomics, Vol 21, Iss S6, Pp 1-15 (2020)
Abstract Background Third-generation single molecule sequencing technologies can sequence long reads, which is advancing the frontiers of genomics research. However, their high error rates prohibit accurate and efficient downstream analysis. This dif
Externí odkaz:
https://doaj.org/article/2aaf8db06acb497388b5c8ef64090310
Publikováno v:
BMC Bioinformatics, Vol 21, Iss S6, Pp 1-12 (2020)
Abstract Background Alignment-free methods for sequence comparisons have become popular in many bioinformatics applications, specifically in the estimation of sequence similarity measures to construct phylogenetic trees. Recently, the average common
Externí odkaz:
https://doaj.org/article/96db9fcf7ab54535b9a6b3d9e2ce192f
Publikováno v:
BMC Bioinformatics, Vol 19, Iss S20, Pp 49-57 (2018)
Abstract Background Atomic details of protein-DNA complexes can provide insightful information for better understanding of the function and binding specificity of DNA binding proteins. In addition to experimental methods for solving protein-DNA compl
Externí odkaz:
https://doaj.org/article/dd0ec7e2855c48a0938dd13350f960d0
Autor:
Chirag Jain, Luis M. Rodriguez-R, Adam M. Phillippy, Konstantinos T. Konstantinidis, Srinivas Aluru
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
Average Nucleotide Identity (ANI) is a robust and useful measure to gauge genetic relatedness between two genomes. Here, the authors develop FastANI, a method to compute ANI using alignment-free approximate sequence mapping, and show 95% ANI is an ac
Externí odkaz:
https://doaj.org/article/1a91648286dc4ad7b362fb1f3a14aece
Publikováno v:
BMC Bioinformatics, Vol 18, Iss S8, Pp 1-8 (2017)
Abstract Background Alignment-free sequence comparison approaches have been garnering increasing interest in various data- and compute-intensive applications such as phylogenetic inference for large-scale sequences. While k-mer based methods are pred
Externí odkaz:
https://doaj.org/article/c26d68c196ec4479abd0302bfad21654
Autor:
Inna Rytsareva, David S. Campo, Yueli Zheng, Seth Sims, Sharma V. Thankachan, Cansu Tetik, Jain Chirag, Sriram P. Chockalingam, Amanda Sue, Srinivas Aluru, Yury Khudyakov
Publikováno v:
BMC Genomics, Vol 18, Iss S4, Pp 1-7 (2017)
Abstract Background Hepatitis C is a major public health problem in the United States and worldwide. Outbreaks of hepatitis C virus (HCV) infections associated with unsafe injection practices, drug diversion, and other exposures to blood are difficul
Externí odkaz:
https://doaj.org/article/0782b1e0473242158598b9802a482245
Autor:
Huaxun Ye, Sanzhen Liu, Buyun Tang, Jiani Chen, Zhouli Xie, Trevor M. Nolan, Hao Jiang, Hongqing Guo, Hung-Ying Lin, Lei Li, Yanqun Wang, Hongning Tong, Mingcai Zhang, Chengcai Chu, Zhaohu Li, Maneesha Aluru, Srinivas Aluru, Patrick S. Schnable, Yanhai Yin
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Brassinosteroid (BR) signalling regulates plant development via the BES1/BZR1 family of transcription factors. Here the authors show that BES1 activity can be modified by the drought-responsive RD26 transcription factor providing a molecular basis fo
Externí odkaz:
https://doaj.org/article/b15887c35469449bbf48efc52b011298
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0122485 (2015)
Our aim was to develop a fast and accurate algorithm for constructing consensus genetic maps for chip-based SNP genotyping data with a high proportion of shared markers between mapping populations. Chip-based genotyping of SNP markers allows producin
Externí odkaz:
https://doaj.org/article/d9aaf15c375d4066a4f066c5f7ae7083