Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Srinivas Abbina"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Cell-based iron overload models provide tremendous utility for the investigations into the pathogenesis of different diseases as well as assessing efficacy of various therapeutic strategies. In the literature, establishing such models vary w
Externí odkaz:
https://doaj.org/article/e95e0ab555f7485cb9aa947b30381adc
Autor:
Chanel C. La, Stephanie A. Smith, Sreeparna Vappala, Reheman Adili, Catherine E. Luke, Srinivas Abbina, Haiming D. Luo, Irina Chafeeva, Matthew Drayton, Louise A. Creagh, Maria de Guadalupe Jaraquemada-Peláez, Nicole Rhoads, Manu Thomas Kalathottukaren, Peter K. Henke, Suzana K. Straus, Caigan Du, Edward M. Conway, Michael Holinstat, Charles A. Haynes, James H. Morrissey, Jayachandran N. Kizhakkedathu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Current treatments to prevent thrombosis, namely anticoagulants and platelets antagonists, remain complicated by the persistent risk of bleeding. Improved therapeutic strategies that diminish this risk would have a huge clinical impact. Anti
Externí odkaz:
https://doaj.org/article/57c0f006deb246efb5209ae08db2193f
Autor:
Rebekka Duhen, Michael Beymer, Shawn M. Jensen, Srinivas Abbina, Suraj Abraham, Nikita Jain, Anitha Thomas, Andrew J. Geall, Hong-Ming Hu, Bernard A. Fox, Andrew D. Weinberg
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
To prevent SARS-CoV-2 infections and generate long-lasting immunity, vaccines need to generate strong viral-specific B and T cell responses. Previous results from our lab and others have shown that immunizations in the presence of an OX40 agonist ant
Externí odkaz:
https://doaj.org/article/b5aca7d566d943a9a319e45e455b3eb4
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Quantification of iron is an important step to assess the iron burden in patients suffering from iron overload diseases, as well as tremendous value in understanding the underlying role of iron in the pathophysiology of these diseases. Curre
Externí odkaz:
https://doaj.org/article/d4248afcc30a4ec694a440329705d47a
Autor:
Srinivas Abbina, Lily E. Takeuchi, Parambath Anilkumar, Kai Yu, Jason C. Rogalski, Rajesh A. Shenoi, Iren Constantinescu, Jayachandran N. Kizhakkedathu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
The blood circulation time is important to the biomedical application of nanomaterials. Here, the authors explore the effect of protein corona formation on the blood residency of nanomaterials and show circulation times are governed by the dynamic re
Externí odkaz:
https://doaj.org/article/1781b338e91c42bfbfee966be2fca34b
Autor:
Parambath Anilkumar, Taylor B. Lawson, Srinivas Abbina, Janne T. A. Mäkelä, Robert C. Sabatelle, Lily E. Takeuchi, Brian D. Snyder, Mark W. Grinstaff, Jayachandran N. Kizhakkedathu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Synthetic globular polymers of several million molecular weight are expected to exhibit unique properties but are difficult to synthesize. Here the authors synthesize such dendritic polymers that show unique lubrication properties and act as molecula
Externí odkaz:
https://doaj.org/article/5df6a98611694f358804cf99738b208f
Autor:
Srinivas Abbina, Usama Abbasi, Arshdeep Gill, Kendrew Wong, Manu Thomas Kalathottukaren, Jayachandran N. Kizhakkedathu
Publikováno v:
ACS Central Science, Vol 5, Iss 5, Pp 917-926 (2019)
Externí odkaz:
https://doaj.org/article/cea1c0b207854783ad706931d374e524
Autor:
Manu T. Kalathottukaren, A. Louise Creagh, Srinivas Abbina, Genmin Lu, Mark J. Karbarz, Anjali Pandey, Pamela B. Conley, Jayachandran N. Kizhakkedathu, Charles Haynes
Publikováno v:
Blood Advances, Vol 2, Iss 16, Pp 2104-2114 (2018)
Abstract: Anticoagulants such as unfractionated heparin (UFH), low-molecular-weight heparins (LMWHs), fondaparinux, and direct oral anticoagulants (DOACs) targeting thrombin (IIa) or factor Xa (FXa) are widely used in prevention and treatment of thro
Externí odkaz:
https://doaj.org/article/290aa8ed658a4f7489db9de78d3374b2
Publikováno v:
Molecules, Vol 25, Iss 18, p 4044 (2020)
Ring opening copolymerization (ROCOP) of epoxides and cyclic anhydrides has become an attractive approach for the synthesis of biodegradable polyesters with various compositions. Encouraged by the efficiency and versatility of a series of amido-oxazo
Externí odkaz:
https://doaj.org/article/f08d008aa7fa4605b5b308af0f6db624
Autor:
Srinivas, Abbina, Usama, Abbasi, Arshdeep, Gill, Heather, Leitch, Jayachandran N, Kizhakkedathu
Publikováno v:
Journal of Controlled Release. 350:857-869
Liver dysfunction and failure account for a major portion of premature deaths in patients suffering from various iron associated pathogeneses, particularly primary and secondary iron overload disorders, despite intensive treatment. The liver is a cen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0690a1d03256f371322f33964f475d26
https://doi.org/10.1016/j.jconrel.2022.08.056
https://doi.org/10.1016/j.jconrel.2022.08.056