Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Srinika Ranasinghe"'
Autor:
Livius Penter, Yang Liu, Jacquelyn O. Wolff, Lin Yang, Len Taing, Aashna Jhaveri, Jackson Southard, Manishkumar Patel, Nicole M. Cullen, Kathleen L. Pfaff, Nicoletta Cieri, Giacomo Oliveira, Seunghee Kim-Schulze, Srinika Ranasinghe, Rebecca Leonard, Taylor Robertson, Elizabeth A. Morgan, Helen X. Chen, Minkyung H. Song, Magdalena Thurin, Shuqiang Li, Scott J. Rodig, Carrie Cibulskis, Stacey Gabriel, Pavan Bachireddy, Jerome Ritz, Howard Streicher, Donna S. Neuberg, F. Stephen Hodi, Matthew S. Davids, Sacha Gnjatic, Kenneth J. Livak, Jennifer Altreuter, Franziska Michor, Robert J. Soiffer, Jacqueline S. Garcia, Catherine J. Wu
Publikováno v:
Blood. 141:1817-1830
The challenge of eradicating leukemia in patients with acute myelogenous leukemia (AML) after initial cytoreduction has motivated modern efforts to combine synergistic active modalities including immunotherapy. Recently, the ETCTN/CTEP 10026 study te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19589bfe9a96752d3a06b523227f37e5
https://doi.org/10.1182/blood.2022018246
https://doi.org/10.1182/blood.2022018246
Autor:
Jonathan D. Schoenfeld, F. Stephen Hodi, Scott J. Rodig, Alexander Spektor, Srinika Ranasinghe, Jason L. Weirather, James Lindsay, Kathleen L. Pfaff, Mariano Severgnini, Alexander A. Merleev, Alina I. Marusina, Emanual Maverakis, Sacha Gnjatic, Seunghee Kim-Schulze, Adrian Mariño-Enríquez, Mansoor M. Ahmed, Helen X. Chen, Howard Streicher, May Cho, Harvey J. Mamon, Elad Sharon, James M. Cleary, Osama E. Rahma, Olatunji B. Alese, Salma K. Jabbour, Anteneh Tesfaye, Ryan D. Gentzler, Claire Manuszak, Katrina Z. Kao, Ryan C. Brennick, Emily M. Thrash, Ana Lako, Anita Giobbie-Hurder, Arta M. Monjazeb
Purpose:Prospective human data are lacking regarding safety, efficacy, and immunologic impacts of different radiation doses administered with combined PD-L1/CTLA-4 blockade.Patients and Methods:We performed a multicenter phase II study randomly assig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::103e97861a6db4ad698277b2b002fe60
https://doi.org/10.1158/1078-0432.c.6531336
https://doi.org/10.1158/1078-0432.c.6531336
Autor:
Jonathan D. Schoenfeld, F. Stephen Hodi, Scott J. Rodig, Alexander Spektor, Srinika Ranasinghe, Jason L. Weirather, James Lindsay, Kathleen L. Pfaff, Mariano Severgnini, Alexander A. Merleev, Alina I. Marusina, Emanual Maverakis, Sacha Gnjatic, Seunghee Kim-Schulze, Adrian Mariño-Enríquez, Mansoor M. Ahmed, Helen X. Chen, Howard Streicher, May Cho, Harvey J. Mamon, Elad Sharon, James M. Cleary, Osama E. Rahma, Olatunji B. Alese, Salma K. Jabbour, Anteneh Tesfaye, Ryan D. Gentzler, Claire Manuszak, Katrina Z. Kao, Ryan C. Brennick, Emily M. Thrash, Ana Lako, Anita Giobbie-Hurder, Arta M. Monjazeb
Supplementary Data and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ef39a1bd1b4d365aae5a1aa7a6475ad
https://doi.org/10.1158/1078-0432.22484139.v1
https://doi.org/10.1158/1078-0432.22484139.v1
Autor:
Matthew S. Davids, Robert J. Soiffer, Emma S. Hathaway, F. Stephen Hodi, Pavan Bachireddy, Magdalena Thurin, Vincent T. Ho, Wandi Zhang, Sarah Nikiforow, Nicoletta Cieri, Jerome Ritz, Stacey Gabriel, Mariano Severgnini, Aashna Jhaveri, X. Shirley Liu, Haesook T. Kim, Jingxin Fu, Kenneth J. Livak, Sacha Gnjatic, Scott J. Rodig, Alexandra Savell, Philippe Armand, Catherine J. Wu, Teddy Huang, Joseph H. Antin, Corey Cutler, Carrie Cibulskis, Livius Penter, Shuqiang Li, Howard Streicher, Donna Neuberg, Srinika Ranasinghe, Matthew Nazzaro, Yi Zhang, Emily M. Thrash, Helen X. Chen, John Koreth, Seunghee Kim-Schulze
Publikováno v:
Blood
Relapsed myeloid disease after allogeneic stem cell transplantation (HSCT) remains largely incurable. We previously demonstrated the potent activity of immune checkpoint blockade in this clinical setting with ipilimumab or nivolumab. To define the mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53e00c031c77e9adaa1a262e1f54cdf2
https://doi.org/10.1182/blood.2021010867
https://doi.org/10.1182/blood.2021010867
Autor:
Livius Penter, Yang Liu, Lin Yang, Len Taing, Aashna Jhaveri, Jackson Southard, Manishkumar Patel, Jacquelyn Wolff, Nicole Cullen, Kathleen Pfaff, Nicoletta Cieri, Giacomo Oliveira, Seunghee Kim-Schulze, Srinika Ranasinghe, Rebecca Leonard, Taylor Robertson, Helen Chen, Magdalena Thurin, Shuqiang Li, Scott J. Rodig, Carrie Cibulskis, Stacey Gabriel, Jerome Ritz, Howard Streicher, Donna S. Neuberg, Stephen Hodi, Sacha Gnjatic, Kenneth J Livak, Jennifer Altreuter, Franziska Michor, Robert J Soiffer, Jacqueline S. Garcia, Catherine J. Wu
Publikováno v:
Blood. 140:10198-10199
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::280261ec92a805ad1ab9774edd08dcc7
https://doi.org/10.1182/blood-2022-157339
https://doi.org/10.1182/blood-2022-157339
Autor:
Jonathan D Schoenfeld, Anita Giobbie-Hurder, Srinika Ranasinghe, Katrina Z Kao, Ana Lako, Junko Tsuji, Yang Liu, Ryan C Brennick, Ryan D Gentzler, Carrie Lee, Joleen Hubbard, Susanne M Arnold, James L Abbruzzese, Salma K Jabbour, Nataliya V Uboha, Kevin L Stephans, Jennifer M Johnson, Haeseong Park, Liza C Villaruz, Elad Sharon, Howard Streicher, Mansoor M Ahmed, Hayley Lyon, Carrie Cibuskis, Niall Lennon, Aashna Jhaveri, Lin Yang, Jennifer Altreuter, Lauren Gunasti, Jason L Weirather, Raymond H Mak, Mark M Awad, Scott J Rodig, Helen X Chen, Catherine J Wu, Arta M Monjazeb, F Stephen Hodi
Publikováno v:
Lancet Oncol
The Lancet. Oncology, vol 23, iss 2
The Lancet. Oncology, vol 23, iss 2
BackgroundPatients with non-small-cell lung cancer (NSCLC) that is resistant to PD-1 and PD-L1 (PD[L]-1)-targeted therapy have poor outcomes. Studies suggest that radiotherapy could enhance antitumour immunity. Therefore, we investigated the potentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fb413a3e2f50d891f3a6467eb8df660
https://pubmed.ncbi.nlm.nih.gov/35358457
https://pubmed.ncbi.nlm.nih.gov/35358457
Autor:
Minkyung Song, Sean C. Bendall, Melissa D. Bowman, James Lindsay, Diane Marie Del Valle, J. Jack Lee, Cathy Rowe, Gerold Bongers, Jenny Peterson-Klaus, James H. Doroshow, Valerie M. Tatard-Leitman, F. Stephen Hodi, Holden T. Maecker, Chia-Chi Chang, Sacha Gnjatic, David Patton, Srinika Ranasinghe, Ethan Cerami, Lyndsay Harris, Jeffrey S. Abrams, Magdalena Thurin, Stacey J Adam, Ignacio I. Wistuba, Rebecca A. Enos, Helen X. Chen, Margaret M. Mooney, Sylvie Janssens, Robert R. Jenq, Elad Sharon, Howard Streicher, Chantale Bernatchez, Mina Pichavant, Joyce Yu, Stephen M. Hewitt, Catherine J. Wu, Beatriz Sanchez-Espiridion, Xiaole Shirley Liu, Radim Moravec, Ming Tang, Gheath Alatrash
Publikováno v:
Clin Cancer Res
Purpose: Immunoprofiling to identify biomarkers and integration with clinical trial outcomes are critical to improving immunotherapy approaches for patients with cancer. However, the translational potential of individual studies is often limited by s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d123c2ad19f463e523105dab86b951fc
https://europepmc.org/articles/PMC8491462/
https://europepmc.org/articles/PMC8491462/
Autor:
Jonathan D. Schoenfeld, Anita Giobbie-Hurder, Srinika Ranasinghe, Katrina Z. Kao, Ana Lako, Junko Tsuji, Yang Liu, Ryan C. Brennick, Ryan Gentzler, Carrie Lee, Joleen Hubbard, James L. Abbruzzese, Salma K. Jabbour, Nataliya Uboha, Kevin Stephans, Jennifer M. Johnson, Haesong Park, Lisa C. Villaruz, Elad Sharon, Howard Streicher, Mansoor Ahmed, Hayley Lyon, Carrie Cibuskis, Niall Lennon, Aashna Jhaveri, Lin Yang, Jennifer Altreuter, Lauren Gunasti, Jason L. Weirather, Raymond H. Mak, Mark M. Awad, Scott J. Rodig, Helen X. Chen, Catherine J. Wu, Arta M. Monjazeb, F. Stephen Hodi
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf93d065b05fbe53a3e25133c1545807
https://doi.org/10.2139/ssrn.3922682
https://doi.org/10.2139/ssrn.3922682
Autor:
Jonathan D. Schoenfeld, Arta M. Monjazeb, Jason L. Weirather, Kathleen L. Pfaff, Emanual Michael Maverakis, James M. Cleary, Srinika Ranasinghe, Ryan D. Gentzler, Mansoor M. Ahmed, Seunghee Kim-Schulze, Sacha Gnjatic, Harvey J. Mamon, Salma K. Jabbour, Anita Giobbie-Hurder, Osama E. Rahma, May Cho, Howard Streicher, Olatunji B. Alese, Anteneh Tesfaye, Alexander Spektor, Katrina Z. Kao, Claire Manuszak, Ana Lako, Helen X. Chen, Ryan C. Brennick, Alexander A. Merleev, Elad Sharon, Emily M. Thrash, Alina I. Marusina, Mariano Severgnini, Adrián Mariño-Enríquez, Stephen Hodi, James Lindsay, Scott J. Rodig
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research, vol 27, iss 9
Clin Cancer Res
Clin Cancer Res
Purpose: Prospective human data are lacking regarding safety, efficacy, and immunologic impacts of different radiation doses administered with combined PD-L1/CTLA-4 blockade. Patients and Methods: We performed a multicenter phase II study randomly as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdd1ffbb7cc5343173ffe532e84ede0e
https://pubmed.ncbi.nlm.nih.gov/34470811
https://pubmed.ncbi.nlm.nih.gov/34470811
Autor:
Daniel J. DeAngelo, Alexandria K Maurer, Vijay G. Sankaran, Catherine J. Wu, Robert J. Soiffer, Caleb A. Lareau, Jacqueline S. Garcia, Livius Penter, Nicoletta Cieri, Jackson Southard, Donna Neuberg, Kenneth J. Livak, Shuqiang Li, Srinika Ranasinghe, Leif S. Ludwig
Publikováno v:
Blood. 138:1689-1689
Reconstitution of donor hematopoiesis after allogeneic hematopoietic stem cell transplantation (HSCT) forms the basis for effective graft-versus-leukemia responses, but mixed chimerism is not an infrequent outcome. How the donor and host hematopoieti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b0a87cace45aa54e75cb786a8d30890
https://doi.org/10.1182/blood-2021-145304
https://doi.org/10.1182/blood-2021-145304