Zobrazeno 1 - 10
of 247
pro vyhledávání: '"Srikumar P, Chellappan"'
Autor:
Yainyrette Rivera-Rivera, Geraldine Vargas, Neha Jaiswal, Angel Núñez-Marrero, Jiannong Li, Dung-Tsa Chen, Steven Eschrich, Marilin Rosa, Joseph O. Johnson, Julie Dutil, Srikumar P. Chellappan, Harold I. Saavedra
Publikováno v:
Cell Division, Vol 17, Iss 1, Pp 1-14 (2022)
Abstract Molecular epidemiology evidence indicates racial and ethnic differences in the aggressiveness and survival of breast cancer. Hispanics/Latinas (H/Ls) and non-Hispanic Black women (NHB) are at higher risk of breast cancer (BC)-related death r
Externí odkaz:
https://doaj.org/article/bc3caee0596a4f7ca187e7de2ddb60a7
Autor:
Yainyrette Rivera-Rivera, Mihaela Marina, Shirley Jusino, Miyoung Lee, Jaleisha Vélez Velázquez, Camille Chardón-Colón, Geraldine Vargas, Jaya Padmanabhan, Srikumar P. Chellappan, Harold I. Saavedra
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Nek2 (NIMA‐related kinase 2) is a serine/threonine-protein kinase that localizes to centrosomes and kinetochores, controlling centrosome separation, chromosome attachments to kinetochores, and the spindle assembly checkpoint. These process
Externí odkaz:
https://doaj.org/article/349186be6236452795f3845aa7cf9050
Autor:
Ray Waters
Publikováno v:
Human Genetics. 126:727-727
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::791ef2ad229b5d7e9197f0bad52a7ab2
https://doi.org/10.1007/s00439-009-0734-6
https://doi.org/10.1007/s00439-009-0734-6
Publikováno v:
Molecular Cancer, Vol 17, Iss 1, Pp 1-16 (2018)
Abstract Background Lung cancer is the leading cause of cancer related deaths and its incidence is highly correlated with cigarette smoking. Nicotine, the addictive component of tobacco smoke, cannot initiate tumors, but can promote proliferation, mi
Externí odkaz:
https://doaj.org/article/20a1916cd114481e80ca34c04bd18a88
Autor:
Shengchen Lin, Chongbiao Huang, Venugopal Gunda, Jianwei Sun, Srikumar P. Chellappan, Zengxun Li, Victoria Izumi, Bin Fang, John Koomen, Pankaj K. Singh, Jihui Hao, Shengyu Yang
Publikováno v:
Cell Reports, Vol 28, Iss 11, Pp 2824-2836.e8 (2019)
Summary: The deregulation of the actin cytoskeleton has been extensively studied in metastatic dissemination. However, the post-dissemination role of the actin cytoskeleton dysregulation is poorly understood. Here, we report that fascin, an actin-bun
Externí odkaz:
https://doaj.org/article/224419c918c949e48a8ec1e471da7e8c
Autor:
Srikumar P. Chellappan, Barbara A. Centeno, Nicholas J. Lawrence, Said M. Sebti, Daniele Pernazza, Dongyu Zhang, Smitha Pillai, Sandeep Singh, Monika Verma, José G. Treviño
PDF file - 1279K, Supplementary Figure 1. PANC-1 and Mia-PaCa cells are highly sensitive to RRD-251. Supplementary Figure 2. RRD-251 enhances the pro-apoptotic effects of gemcitabine. TABLE 1. Varying sensitivity of pancreatic cancer cells to RRD-251
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65a6df2aab7e015427aac1a1837da16b
https://doi.org/10.1158/1535-7163.22498470.v1
https://doi.org/10.1158/1535-7163.22498470.v1
Autor:
Keiran S.M. Smalley, J. William Harbour, Jonathan D. Licht, Uwe Rix, Silvya Stuchi Maria-Engler, Srikumar P. Chellappan, John M. Koomen, Bin Fang, Biswarup Saha, Fumi Kinose, Michael A. Durante, Michael F. Emmons, Fernanda Faião-Flores
Supplemental Figure 1: Gene ontology network analysis of uveal melanoma cells following MEKi treatment (24h) and ABPP. Supplemental Figure 2: ET-3 increases nuclear accumulation of YAP in 92.1, Mel270, MP41 and OMM1 cells. Supplemental Figure 3: ET-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b7b3c2c75bdf283a97ad482de2b351d
https://doi.org/10.1158/1078-0432.22471901
https://doi.org/10.1158/1078-0432.22471901
Autor:
Keiran S.M. Smalley, J. William Harbour, Jonathan D. Licht, Uwe Rix, Silvya Stuchi Maria-Engler, Srikumar P. Chellappan, John M. Koomen, Bin Fang, Biswarup Saha, Fumi Kinose, Michael A. Durante, Michael F. Emmons, Fernanda Faião-Flores
Supplementary Table S1- Antibodies used for protein expression in western blotting experiments Supplementary Table S2 - Assays used for gene expression in RT-qPCR experiments Supplementary Table S3 - Antibodies used for protein expression in immunofl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20b6fa70918d2735b28b48bcd1f4dcb8
https://doi.org/10.1158/1078-0432.22471898
https://doi.org/10.1158/1078-0432.22471898
Autor:
Keiran S.M. Smalley, J. William Harbour, Jonathan D. Licht, Uwe Rix, Silvya Stuchi Maria-Engler, Srikumar P. Chellappan, John M. Koomen, Bin Fang, Biswarup Saha, Fumi Kinose, Michael A. Durante, Michael F. Emmons, Fernanda Faião-Flores
Purpose:The clinical use of MEK inhibitors in uveal melanoma is limited by the rapid acquisition of resistance. This study has used multiomics approaches and drug screens to identify the pan-HDAC inhibitor panobinostat as an effective strategy to lim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18a6c9d3938006c6153d7b74edfa41ea
https://doi.org/10.1158/1078-0432.c.6528053
https://doi.org/10.1158/1078-0432.c.6528053
Autor:
Jose G. Trevino, Smitha Pillai, Sateesh Kunigal, Sandeep Singh, William J. Fulp, Barbara A. Centeno, Srikumar P. Chellappan
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 12, Pp 1102-1114 (2012)
Smoking is a significant risk factor for pancreatic cancer, but the molecular mechanisms by which tobacco smoke components promote the growth and progression of these cancers are not fully understood. While nicotine, the addictive component of tobacc
Externí odkaz:
https://doaj.org/article/eb81c83ad596455faa08f82d00e26212