Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Srikar R. Malireddy"'
Autor:
Stephen D. Hall, Srikar R. Malireddy, Raj Vuppalanchi, Mitchell A. Hamman, Sara K. Quinney, Naga Chalasani, J. Christopher Gorski
Publikováno v:
European Journal of Clinical Pharmacology. 69:439-448
To determine the extent and time-course of hepatic and intestinal cytochrome P450 3A (CYP3A) inactivation due to the mechanism-based inhibitor clarithromycin.Intestinal and hepatic CYP3A inhibition was examined in 12 healthy volunteers following the
Autor:
M. J. Waddell, E. Gabriela Chiorean, Bryan P. Schneider, Srikar R. Malireddy, Christopher Sweeney, Stephen D. Hall, David R. Jones, Melissa I. Sloop, Anne Younger, Menggang Yu
Publikováno v:
Cancer Chemotherapy and Pharmacology. 66:441-448
To define the maximum-tolerated dose (MTD) for weekly paclitaxel administered in combination with daily vatalanib (PTK787/ZK 222584, PTK/ZK) and assess for a drug-drug interaction.Patients were treated with escalating doses of weekly paclitaxel (75-8
Publikováno v:
Transplantation Proceedings. 40:1789-1791
Background The significant interindividual and intraindividual variability in the blood concentrations of the most commonly used calcineurin inhibitors such as tacrolimus and cyclosporine makes the exact dosing of these agents in transplant recipient