Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Srikanth Vedamoorthyrao"'
Autor:
Pompeo Volpe, Srikanth Vedamoorthyrao, Serge Viatchenko-Karpinski, Alessandra Nori, Giorgia Valle, Radmila Terentyeva, Zuzana Kubalova, Dmitry Terentyev, Donald M. Bers, Sandor Gyorke, Simon C. Williams
Publikováno v:
Biophysical Journal. 95(4):2037-2048
Cardiac calsequestrin (CASQ2) is an intrasarcoplasmic reticulum (SR) low-affinity Ca-binding protein, with mutations that are associated with catecholamine-induced polymorphic ventricular tachycardia (CPVT). To better understand how CASQ2 mutants cau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b77c18b10a4f5d21dee931534556307b
Autor:
Srikanth Vedamoorthyrao, Serge Viatchenko-Karpinski, Sridhar Oduru, Inna Györke, Simon C. Williams, Sandor Gyorke, Dmitry Terentyev
Publikováno v:
The Journal of Physiology. 583:71-80
In cardiac muscle, intracellular Ca2+ release is controlled by a number of proteins including the ryanodine receptor (RyR2), calsequestrin (CASQ2), triadin-1 (Trd) and junctin (Jn) which form a complex in the junctional sarcoplasmic reticulum (SR) me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8d74567979982d6718841d192d9ab5f
https://doi.org/10.1113/jphysiol.2007.136879
https://doi.org/10.1113/jphysiol.2007.136879
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 105(47)
The physiological relevance of smooth muscle myosin isoforms SM1 and SM2 has not been understood. In this study we generated a mouse model specifically deficient in SM2 myosin isoform but expressing SM1, using an exon-specific gene targeting strategy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98a341337e6b3b0db0443dd953aa4c94
https://pubmed.ncbi.nlm.nih.gov/19011095
https://pubmed.ncbi.nlm.nih.gov/19011095
Publikováno v:
Nature Precedings
The smooth muscle myosin heavy chains (SMHC) are motor proteins powering smooth muscle contraction. Alternate splicing of SHMC gene at the C-terminus produces SM1, and SM2 myosin isoforms; SM2 (200 kDa) contains a unique 9-amino-acid sequence at the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1c0aa0073d0c16a37ad50e291bc37bb
https://doi.org/10.1038/npre.2008.1643.1
https://doi.org/10.1038/npre.2008.1643.1
Autor:
Dmitry, Terentyev, Serge, Viatchenko-Karpinski, Srikanth, Vedamoorthyrao, Sridhar, Oduru, Inna, Györke, Simon C, Williams, Sandor, Györke
Publikováno v:
The Journal of physiology. 583(Pt 1)
In cardiac muscle, intracellular Ca2+ release is controlled by a number of proteins including the ryanodine receptor (RyR2), calsequestrin (CASQ2), triadin-1 (Trd) and junctin (Jn) which form a complex in the junctional sarcoplasmic reticulum (SR) me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c67ee62130a92beb6243aaf91fa53868
https://pubmed.ncbi.nlm.nih.gov/18048447
https://pubmed.ncbi.nlm.nih.gov/18048447
Autor:
Srikanth Vedamoorthyrao, Clara Franzini-Armstrong, Ning Li, Sandor Gyorke, Wessel P. Dirksen, Muthu Periasamy, Véronique A. Lacombe, Nipavan Chiamvimonvat, Anuradha Kalyanasundaram, Cynthia A. Carnes, Mei Chi, Zhixiang Zhou, Dmitry Terentyev, Serge Viatchenko-Karpinski
Objective: A naturally-occurring mutation in cardiac calsequestrin (CASQ2) at amino acid 307 was discovered in a highly inbred family and hypothesized to cause Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT). The goal of this study was t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62ebbe675405380f18a08d0d951011a1
https://europepmc.org/articles/PMC2717009/
https://europepmc.org/articles/PMC2717009/
Autor:
Dmitry Terentyev, Srikanth Vedamoorthyrao, Inna Györke, Serge Viatchenko-Karpinski, Giorgia Valle, Massimo Santoro, Nico A. Blom, Zuzana Kubalova, Carlo Napolitano, Radmila Terentyeva, Pompeo Volpe, Simon C. Williams, Alessandra Nori, Silvia G. Priori, Sandor Gyorke
Publikováno v:
Circulation research, 98(9), 1151-1158. Lippincott Williams and Wilkins
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a familial arrhythmogenic disorder associated with mutations in the cardiac ryanodine receptor ( RyR2 ) and cardiac calsequestrin ( CASQ2 ) genes. Previous in vitro studies suggested tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5d4c8b76708d89f2d2e28cb282083d0
https://pure.amc.nl/en/publications/abnormal-interactions-of-calsequestrin-with-the-ryanodine-receptor-calcium-release-channel-complex-linked-to-exerciseinduced-sudden-cardiac-death(c83a97f5-5aa1-4afa-9887-7579053b92e4).html
https://pure.amc.nl/en/publications/abnormal-interactions-of-calsequestrin-with-the-ryanodine-receptor-calcium-release-channel-complex-linked-to-exerciseinduced-sudden-cardiac-death(c83a97f5-5aa1-4afa-9887-7579053b92e4).html
Publikováno v:
The FASEB Journal. 22:145-145
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::150b3733780bf013070ac3ac66296200
https://doi.org/10.1096/fasebj.22.2_supplement.145
https://doi.org/10.1096/fasebj.22.2_supplement.145