Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Srikanth Sadhu"'
VapC12 ribonuclease toxin modulates host immune response during Mycobacterium tuberculosis infection
Autor:
Shaifali Tyagi, Srikanth Sadhu, Taruna Sharma, Abhijit Paul, Manitosh Pandey, Vaibhav Kumar Nain, Deepak Kumar Rathore, Samrat Chatterjee, Amit Awasthi, Amit Kumar Pandey
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Mechanistic understanding of antibiotic persistence is a prerequisite in controlling the emergence of MDR cases in Tuberculosis (TB). We have reported that the cholesterol-induced activation of VapC12 ribonuclease is critical for disease persistence
Externí odkaz:
https://doaj.org/article/f16038945c2344a38c75ef56c196a00b
Autor:
Zaigham Abbas Rizvi, Jyotsna Dandotiya, Srikanth Sadhu, Ritika Khatri, Janmejay Singh, Virendra Singh, Neeta Adhikari, Kritika Sharma, Vinayake Das, Amit Kumar Pandey, Bhabatosh Das, Guruprasad Medigeshi, Shalendra Mani, Shinjini Bhatnagar, Sweety Samal, Anil Kumar Pandey, Pramod Kumar Garg, Amit Awasthi
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract A recently emerged sub-lineage of Omicron, BA.5, together with BA.4, caused a fifth wave of coronavirus disease (COVID-19) in South Africa and subsequently emerged as a predominant strain globally due to its high transmissibility. The lethal
Externí odkaz:
https://doaj.org/article/fa2213b252c144c39434f971c7aca2bd
Autor:
Srikanth Sadhu, Rajdeep Dalal, Jyotsna Dandotiya, Akshay Binayke, Virendra Singh, Manas Ranjan Tripathy, Vinayaka Das, Sandeep Goswami, Shakti Kumar, Zaigham Abbas Rizvi, Amit Awasthi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract SARS-CoV-2 infection is known for causing broncho-alveolar inflammation. Interleukin 9 (IL-9) induces airway inflammation and bronchial hyper responsiveness in respiratory viral illnesses and allergic inflammation, however, IL-9 has not been
Externí odkaz:
https://doaj.org/article/04743ba11185487a96108ea58019d13c
Autor:
Shuvra Shekhar Roy, Shalu Sharma, Zaigham Abbas Rizvi, Dipanjali Sinha, Divya Gupta, Mercy Rophina, Paras Sehgal, Srikanth Sadhu, Manas Ranjan Tripathy, Sweety Samal, Souvik Maiti, Vinod Scaria, Sridhar Sivasubbu, Amit Awasthi, Krishnan H. Harshan, Sanjeev Jain, Shantanu Chowdhury
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
The COVID-19 pandemic caused by SARS-CoV-2 has caused millions of infections and deaths worldwide. Limited treatment options and the threat from emerging variants underline the need for novel and widely accessible therapeutics. G-quadruplexes (G4s) a
Externí odkaz:
https://doaj.org/article/be185dc57a37426ca40b3079c5373adf
Autor:
Zaigham Abbas Rizvi, Prabhakar Babele, Upasna Madan, Srikanth Sadhu, Manas Ranjan Tripathy, Sandeep Goswami, Shailendra Mani, Madhu Dikshit, Amit Awasthi
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Cytokine release syndrome (CRS) due to severe acute respiratory coronavirus-2 (SARS-CoV-2) infection leads to life-threatening pneumonia which has been associated with coronavirus disease (COVID-19) pathologies. Centuries-old Asian traditional medici
Externí odkaz:
https://doaj.org/article/98d95fd42fa24d40b82561b1cd7ed89a
Autor:
Zaigham Abbas Rizvi, Prabhakar Babele, Srikanth Sadhu, Upasna Madan, Manas Ranjan Tripathy, Sandeep Goswami, Shailendra Mani, Sachin Kumar, Amit Awasthi, Madhu Dikshit
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Severe coronavirus disease (COVID-19) is accompanied by acute respiratory distress syndrome and pulmonary pathology, and is presented mostly with an inflammatory cytokine release, a dysregulated immune response, a skewed neutrophil/lymphocyte ratio,
Externí odkaz:
https://doaj.org/article/e88e66ddc64e468399cec9b4cecd50af
Publikováno v:
American Heart Journal Plus, Vol 13, Iss , Pp 100088- (2022)
Study objectives: The objectives of this study were to identify independent predictors for moderate/accentuated coronary artery calcium (CAC) score and compare patients who self-referred for CAC Computed Tomography (CT) testing to those who were prov
Externí odkaz:
https://doaj.org/article/c480b5e1787848b399cbde9968fd314c
Autor:
Zaigham Abbas Rizvi, Rajdeep Dalal, Srikanth Sadhu, Akshay Binayke, Jyotsna Dandotiya, Yashwant Kumar, Tripti Shrivastava, Sonu Kumar Gupta, Suruchi Aggarwal, Manas Ranjan Tripathy, Deepak Kumar Rathore, Amit Kumar Yadav, Guruprasad R Medigeshi, Amit Kumar Pandey, Sweety Samal, Shailendra Asthana, Amit Awasthi
Publikováno v:
eLife, Vol 11 (2022)
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in the Golden Syrian hamster causes lung pathology that resembles human coronavirus disease (COVID-19). However, extrapulmonary pathologies associated with SARS-CoV-2 infection an
Externí odkaz:
https://doaj.org/article/78b2b9d894bf4efaab700a2327c7617c
Autor:
Srikanth Sadhu, Zaigham Abbas Rizvi, Ramendra Pati Pandey, Rajdeep Dalal, Deepak Kumar Rathore, Bhoj Kumar, Manitosh Pandey, Yashwant Kumar, Renu Goel, Tushar K. Maiti, Atul Kumar Johri, Ashutosh Tiwari, Amit Kumar Pandey, Amit Awasthi
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The global rise of antibiotic-resistant strains of Salmonella has necessitated the development of alternative therapeutic strategies. Recent studies have shown that targeting host factors may provide an alternative approach for the treatment of intra
Externí odkaz:
https://doaj.org/article/22c7efdf03764ebb9156327958ab8676
Autor:
Sakshi Malik, Srikanth Sadhu, Srikanth Elesela, Ramendra Pati Pandey, Amanpreet Singh Chawla, Deepak Sharma, Lipsa Panda, Deepak Rathore, Balram Ghosh, Vineet Ahuja, Amit Awasthi
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
The transcription factor Foxo1 can control regulatory T cell and Th1 function. Here the authors show that Foxo1 is also critical for IL-9 production by Th9 cells and other IL-9-producing cells.
Externí odkaz:
https://doaj.org/article/7ed2be0d99eb4a228e15de298dba3526