Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Srikanth Ravichandran"'
Autor:
Céline Barlier, Diego Barriales, Alexey Samosyuk, Sascha Jung, Srikanth Ravichandran, Yulia A. Medvedeva, Juan Anguita, Antonio del Sol
Publikováno v:
Cell Death and Disease, Vol 12, Iss 9, Pp 1-9 (2021)
Abstract Immunomodulation strategies are crucial for several biomedical applications. However, the immune system is highly heterogeneous and its functional responses to infections remains elusive. Indeed, the characterization of immune response parti
Externí odkaz:
https://doaj.org/article/c7f2cf9941e44be6a03cff557f5065c5
Autor:
Maria Angeliki S. Pavlou, Kartikeya Singh, Srikanth Ravichandran, Rashi Halder, Nathalie Nicot, Cindy Birck, Luc Grandbarbe, Antonio del Sol, Alessandro Michelucci
Publikováno v:
Cells, Vol 12, Iss 6, p 948 (2023)
Astrocytes arise from multipotent neural stem cells (NSCs) and represent the most abundant cell type of the central nervous system (CNS), playing key roles in the developing and adult brain. Since the differentiation of NSCs towards a gliogenic fate
Externí odkaz:
https://doaj.org/article/4ae1f9a0a8534e68a634bc2f08633b78
Autor:
Satoshi Okawa, Carmen Saltó, Srikanth Ravichandran, Shanzheng Yang, Enrique M. Toledo, Ernest Arenas, Antonio del Sol
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Gaining insight into cell identities from single cell RNA-seq data remains a challenge. Here, the authors introduce an approach to identify transcription factors (TFs) that synergistically determine cellular identities, and demonstrate its ability to
Externí odkaz:
https://doaj.org/article/1b7c6baab5e84bcfa07a16f64922ceec
Publikováno v:
Stem Cell Research, Vol 17, Iss 2, Pp 406-412 (2016)
Recent reports indicate a dominant role for cellular microenvironment or niche for stably maintaining cellular phenotypic states. Identification of key niche mediated signaling that maintains stem cells in specific phenotypic states remains a challen
Externí odkaz:
https://doaj.org/article/4e33ccccde48427a9c0d5b2cbc934558
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Alzheimer's disease (AD) is a major neurodegenerative disease and is one of the most common cause of dementia in older adults. Among several factors, neuroinflammation is known to play a critical role in the pathogenesis of chronic neurodegenerative
Externí odkaz:
https://doaj.org/article/a6ec0764e84e44329febb5f2fbe0f232
Autor:
Siddiqui Zaved, Jayaswal Shilpi, Srikanth Ravichandran, Dua Raina, Kumar Dhiraj, Rao Kanury VS
Publikováno v:
BMC Research Notes, Vol 1, Iss 1, p 81 (2008)
Abstract Background Although reciprocal regulation of protein phosphorylation represents a key aspect of signal transduction, a larger perspective on how these various interactions integrate to contribute towards signal processing is presently unclea
Externí odkaz:
https://doaj.org/article/1b59728c35f24dcb9c7629889d8ece3a
Autor:
Stephen R. Brooks, Hong-Wei Sun, Vittorio Sartorelli, Kan Jiang, Marco Sandri, Laura Ortet, Stefania Dell'Orso, Srikanth Ravichandran, Sonia Alonso-Martin, Aster H. Juan, Laura García-Prat, Victoria Moiseeva, Marta Flández, Eusebio Perdiguero, Vanessa Ruiz-Bonilla, Pura Muñoz-Cánoves, Elena Rebollo, Mercè Jardí, Antonio Musarò, Xiaotong Hong, Antonio del Sol, Silvia Campanario
Publikováno v:
Nature Cell Biology
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
Tissue regeneration declines with ageing but little is known about whether this arises from changes in stem-cell heterogeneity. Here, in homeostatic skeletal muscle, we identify two quiescent stem-cell states distinguished by relative CD34 expression
Autor:
Antonio del Sol, Srikanth Ravichandran, Yulia A. Medvedeva, Alexey Samosyuk, Sascha Jung, Céline Barlier, Diego Barriales, Juan Anguita
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 9, Pp 1-9 (2021)
Cell Death and Disease, Vol 12, Iss 9, Pp 1-9 (2021)
Immunomodulation strategies are crucial for several biomedical applications. However, the immune system is highly heterogeneous and its functional responses to infections remains elusive. Indeed, the characterization of immune response particularitie
Autor:
Casey A. Gifford, Amelia Schricker, Sanjeev S. Ranade, T. Yvanka de Soysa, Antonio del Sol, Deepak Srivastava, Yadong Huang, Satoshi Okawa, Srikanth Ravichandran, Hazel T. Salunga
Publikováno v:
Nature
Organogenesis involves integration of diverse cell types; dysregulation of cell-type-specific gene networks results in birth defects, which affect 5% of live births. Congenital heart defects are the most common malformations, and result from disrupti