Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Srikanth Kodali"'
Publikováno v:
Autophagy Reports, Vol 1, Iss 1, Pp 165-169 (2022)
The formation of long-lived immune memory cells specific for pathogens is critical for the establishment of long-term immune protection against future infections. BNIP3L/NIX and BNIP3, two functionally redundant BCL2 family members required for mitop
Externí odkaz:
https://doaj.org/article/2008754c59e74ccb9cfdc3ee40a1f887
Autor:
Ludovica Proietti, Srikanth Kodali, Gemma Valcarcel, Anna Vanessa Lopez-Rubio, Patrizia Pessina, Thomas Eder, Yingzhi Cui, Florencia Levin, Bernhard Alber, Gabriele Manhart, Alessandro Fatica, Jose Louis Sardina, Bruno DI Stefano, Florian Grebien
Publikováno v:
HemaSphere, Vol 7, p e8249393 (2023)
Externí odkaz:
https://doaj.org/article/9d84021610664209a77b5009bd067c54
Autor:
Dongpeng Wang, Wei Wu, Elsa Callen, Raphael Pavani, Nicholas Zolnerowich, Srikanth Kodali, Dali Zong, Nancy Wong, Santiago Noriega, William J. Nathan, Gabriel Matos-Rodrigues, Raj Chari, Michael J. Kruhlak, Ferenc Livak, Michael Ward, Keith Caldecott, Bruno Di Stefano, André Nussenzweig
Publikováno v:
Science
Neurons harbor high levels of single-strand DNA breaks (SSBs) that are targeted to neuronal enhancers, but the source of this endogenous damage remains unclear. Using two systems of postmitotic lineage specification—induced pluripotent stem cell–
Publikováno v:
Cell Stem Cell. 30:335-337
Publikováno v:
J Immunol
The development of long-lived immune memory cells against pathogens is critical for the success of vaccines to establish protection against future infections. However, the mechanisms governing the long-term survival of immune memory cells remain to b
Publikováno v:
J Immunol
In response to T cell–dependent Ag encounter, naive B cells develop into germinal center (GC) B cells, which can further differentiate into Ab-secreting plasma cells or memory B cells. GC B cells are short lived and are prone to caspase-mediated ap
Autor:
Hin Ching Lo, Hai Wang, Weijie Zhang, Jeffrey M. Rosen, Bradley Pingel, Jun Liu, Silke Paust, Zhan Xu, Xiang Zhang, Srikanth Kodali, Ik Sun Kim, Joel R. Neilson, Sarah Hein, Sergio Aguirre, Alexander S. Krupnick, Aaron M. Muscarella
Publikováno v:
Nature cancer. 1(7)
Polyclonal metastases frequently arise from clusters of circulating tumor cells (CTCs). CTC clusters metastasize better than single CTCs, but the underlying molecular mechanisms are poorly understood. Here, we show that polyclonal metastatic seeds ex
Autor:
Srikanth Kodali
Publikováno v:
The Journal of Immunology. 204:155.7-155.7
Immunological memory preserved by long-lived memory cells forms the basis for long-term protection by the adaptive immune system against repeat infections. Autophagy is crucial for the longevity of memory cells, though the molecular mechanisms for th
Publikováno v:
The Journal of Immunology. 194:2607-2615
Autophagy is required for the long-term maintenance of Ag-specific memory B cells. However, whether autophagy is also important for the initial formation of memory B cells remains unclear. In this study, we show that newly generated memory B cells do
Publikováno v:
Mitochondrion. 41
B cells are responsible for protective antibody production after differentiation into antibody-secreting cells during humoral immune responses. From early B cell development in the bone marrow, to their maturation in the periphery, activation in the