Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Srikanth Budnar"'
Autor:
Xuan Liang, Srikanth Budnar, Shafali Gupta, Suzie Verma, Siew-Ping Han, Michelle M. Hill, Roger J. Daly, Robert G. Parton, Nicholas A. Hamilton, Guillermo A. Gomez, Alpha S. Yap
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Epithelial cell-cell adhesions are contractile junctions, but whether contractility can be down-regulated is not known. Here the authors report how tyrosine dephosphorylation of the cytoskeletal scaffold, cortactin, recruits the RhoA antagonist SRGAP
Externí odkaz:
https://doaj.org/article/825f4db4af8b457a93e1d6628f784ef4
Autor:
Rashmi Priya, Guillermo A Gomez, Srikanth Budnar, Bipul R Acharya, Andras Czirok, Alpha S Yap, Zoltan Neufeld
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 3, p e1005411 (2017)
Mechanical coherence of cell layers is essential for epithelia to function as tissue barriers and to control active tissue dynamics during morphogenesis. RhoA signaling at adherens junctions plays a key role in this process by coupling cadherin-based
Externí odkaz:
https://doaj.org/article/3e090f98abff4b48a5eb1481ba64b9e5
Autor:
Xuan Liang, Srikanth Budnar, Shafali Gupta, Suzie Verma, Siew-Ping Han, Michelle M. Hill, Roger J. Daly, Robert G. Parton, Nicholas A. Hamilton, Guillermo A. Gomez, Alpha S. Yap
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-1 (2017)
A correction to this article has been published and is linked from the HTML version of this article.
Externí odkaz:
https://doaj.org/article/70bb9f2deed44dfa8fed35f2c4526279
Autor:
Michele Bastiani, Harriet P. Lo, Jan Steyaert, Rachel S. Gormal, Els Pardon, Merja Joensuu, Srikanth Budnar, Adekunle T. Bademosi, James Rae, Ailisa Blum, Jean Giacomotto, Pranesh Padmanabhan, Frederic A. Meunier, Geoffrey J. Goodhill, Alpha S. Yap, Tristan P. Wallis, Massimo A. Hilliard, Walter G. Thomas, Ravikiran Kasula, Robert G. Parton, Charles Ferguson, Sean Coakley
Publikováno v:
Proc Natl Acad Sci U S A
None of the current superresolution microscopy techniques can reliably image the changes in endogenous protein nanoclustering dynamics associated with specific conformations in live cells. Single-domain nanobodies have been invaluable tools to isolat
Autor:
Abinaya Rajendran, Hema P Bagul, Babukrishna Maniyadath, Arushi Shukla, Tandrika Chattopadhyay, Arindam Chakraborty, Srikanth Budnar, Ullas Kolthur-Seetharam, Siddhesh S. Kamat, Namrata Shukla
Publikováno v:
Proc Natl Acad Sci U S A
Inefficient physiological transitions are known to cause metabolic disorders. Therefore, investigating mechanisms that constitute molecular switches in a central metabolic organ like the liver becomes crucial. Specifically, upstream mechanisms that c
Autor:
Benjamin M. Hogan, Anne K. Lagendijk, Luke Coburn, Guillermo A. Gomez, Alpha S. Yap, Irin-Maya Schouwenaar, Srikanth Budnar, Jessica L. Teo, Suzie Verma, Thomas E. Hall, Robert W. McLachlan, Vanesa M. Tomatis, Robert G. Parton
Publikováno v:
Molecular Biology of the Cell
Epithelia can eliminate apoptotic cells by apical extrusion. This is a complex morphogenetic event where expulsion of the apoptotic cell is accompanied by rearrangement of its immediate neighbors to form a rosette. A key mechanism for extrusion is co
Autor:
Kate E. Cavanaugh, Michael F. Staddon, Theresa A. Chmiel, Robert Harmon, Srikanth Budnar, Alpha S. Yap, Shiladitya Banerjee, Margaret L. Gardel
Publikováno v:
Curr Biol
Tissue morphogenesis arises from the culmination of changes in cell-cell junction length. Mechanochemical signaling in the form of RhoA underlies these ratcheted contractions, which occur asymmetrically. The underlying mechanisms of asymmetry remain
Autor:
Xuan Liang, Guillermo A. Gomez, Alpha S. Yap, Philippe Marcq, Kinga Duszyc, Ivar Noordstra, Shafali Gupta, Srikanth Budnar, Suzie Verma
Epithelia migrate as physically coherent populations of cells. Earlier studies revealed that mechanical stress accumulates in these cellular layers as they move. These stresses are characteristically tensile in nature and have often been inferred to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fdb7c23aced4d590c64d8e6f04801d7
https://doi.org/10.1101/2021.04.08.439097
https://doi.org/10.1101/2021.04.08.439097
Autor:
Alpha S. Yap, Ivar Noordstra, Shafali Gupta, Xuan Liang, Kinga Duszyc, Philippe Marcq, Srikanth Budnar, Suzie Verma, Guillermo A. Gomez
Publikováno v:
Journal of cell science. 134(17)
Epithelia migrate as physically coherent populations of cells. Previous studies have revealed that mechanical stress accumulates in these cellular layers as they move. These stresses are characteristically tensile in nature and have often been inferr
Autor:
Srikanth Budnar, Kate E. Cavanaugh, Robert M. Harmon, Theresa A. Chmiel, Shiladitya Banerjee, Michael F. Staddon, Margaret L. Gardel, Alpha S. Yap
Tissue morphogenesis often arises from the culmination of discrete changes in cell-cell junction behaviors, namely ratcheted junction contractions that lead to collective cellular rearrangements. Mechanochemical signaling in the form of RhoA underlie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfeb700b0e9f6913bc6b6cb016ab5791
https://doi.org/10.1101/2021.02.26.433093
https://doi.org/10.1101/2021.02.26.433093