Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Srikanth Battu"'
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Nutrient sensor GCN2 plays a crucial role in the maintenance of cellular homeostasis during the condition of amino acid deprivation. Dysfunction in the GCN2 signaling underlies several chronic metabolic diseases. Recent studies highlight the anti-vir
Externí odkaz:
https://doaj.org/article/888b4244ec684bf0a08333d1b35acaa6
Autor:
Srikanth Battu, Sumbul Afroz, Jeevan Giddaluru, Saima Naz, Weishan Huang, Saratchandra Singh Khumukcham, Rafiq Ahmad Khan, Saleem Yousuf Bhat, Insaf Ahmed Qureshi, Bramanandam Manavathi, Aleem Ahmed Khan, Avery August, Seyed Ehtesham Hasnain, Nooruddin Khan
Publikováno v:
PLoS Biology, Vol 16, Iss 4, p e2005317 (2018)
Activation of the amino acid starvation response (AAR) increases lifespan and acute stress resistance as well as regulates inflammation. However, the underlying mechanisms remain unclear. Here, we show that activation of AAR pharmacologically by Halo
Externí odkaz:
https://doaj.org/article/4475e910e3734fa4a2d29e1cbe9801cb
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Metabolic adaptation to the changing nutrient levels in the cellular microenvironment plays a decisive role in the maintenance of homeostasis. Eukaryotic cells are equipped with nutrient sensors, which sense the fluctuating nutrients levels and accor
Externí odkaz:
https://doaj.org/article/4836b7feadfc4dc595005384f53430bb
Autor:
Harshavardhan Bhuktar, Sharda Shukla, Kumar Reddy Kakularam, Srikanth Battu, Manupati Srikanth, Susmita Srivastava, Raghavender Medishetti, Pooja Ram, P.C. Jagadish, Mahaboobkhan Rasool, Sandipan Chakraborty, Nooruddin Khan, Pallu Reddanna, Srinivas Oruganti, Manojit Pal
Publikováno v:
Bioorganic Chemistry. 138:106606
Publikováno v:
Future microbiology. 17
Macrophages are important cells that regulate various innate functions. Macrophages after engulfment of pathogens proceed for phagosome maturation and finally fuse with lysosomes to kill pathogens. Although pathogen degradation is one of the importan
Autor:
Aejaz Habeeb, Jeevan Giddaluru, Rafiq Ahmad Khan, Srikanth Battu, Aleem Ahmed Khan, Nooruddin Khan, Sumbul Afroz, Sandeep Kumar Vishwakarma, Vishnupriya Satti, Saima Naz
Publikováno v:
European Journal of Immunology. 49:277-289
Immune cells sense and programme its cellular machinery appropriately to the environmental changes through the activation of cytoprotective adaptive pathway so-called the "integrated stress response (ISR)". However, the mechanisms implicated in ISR-i
Autor:
Mabu P. Subahan, Srikanth Battu, Aleem Ahmed Khan, Saima Naz, Jeevan Giddaluru, Vishnupriya Satti, Rafiq Ahmad Khan, Nooruddin Khan, Sandeep Kumar Vishwakarma
Publikováno v:
Cellular Immunology. 334:42-48
Ulcerative colitis (UC) is a persistent inflammatory illness, which is clinically categorised as Inflammatory bowel disease (IBD), affecting millions of people worldwide. The precise cause behind the pathology of the disease remains unknown. However,
Autor:
Srikanth Battu, Gillipsie Minhas, Sumbul Afroz, Avery August, Shama, Nooruddin Khan, Weishan Huang, Sabrina Solouki, Jessica P. Elmore, Shaikh Matin
Publikováno v:
Sci Signal
Specific reduction in the intake of proteins or amino acids (AAs) offers enormous health benefits, including increased life span, protection against age-associated disorders, and improved metabolic fitness and immunity. Cells respond to conditions of
Autor:
Pradip Paik, Himadri Medhi, Sumbul Afroz, Srikanth Battu, Gillipsie Minhas, Jeevan Giddaluru, Somedutta Maity, Koushi Kumar, Nooruddin Khan
Publikováno v:
Nanoscale. 9:14641-14653
The application of nanotechnology in vaccinology has fuelled rapid advancement towards the design and development of nanovaccines. Nanoparticles have been found to enhance vaccine efficacy through the spatiotemporal orchestration of antigen delivery
Publikováno v:
Cytokine. 123:154780
Dengue virus poses a considerable clinical problem, with the four closely related serotypes of dengue virus (DENV) infecting around 50–100 million people per year world-wide. The drastic increase in the dengue infection could be partly attributed t