Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Srikanth Barkeer"'
Autor:
Srikanth Barkeer, Seema Chugh, Saswati Karmakar, Garima Kaushik, Sanchita Rauth, Satyanarayana Rachagani, Surinder K. Batra, Moorthy P. Ponnusamy
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-15 (2018)
Abstract Background Glycosylation plays a critical role in the aggressiveness of pancreatic cancer (PC). Emerging evidences indicate significant involvement of cancer stem cells (CSCs) in PC aggressiveness. However, the importance of glycosylation in
Externí odkaz:
https://doaj.org/article/70214dd4c5ac4e30a1cde8d00b179290
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 20, Iss 8, Pp 813-825 (2018)
Aberrant glycosylation plays a critical role in tumor aggressiveness, progression, and metastasis. Emerging evidence associates cancer initiation and metastasis to the enrichment of cancer stem cells (CSCs). Several universal markers have been identi
Externí odkaz:
https://doaj.org/article/253199de21454c809382681013622070
Autor:
Radha Pujari, Sachin M Eligar, Natesh Kumar, Srikanth Barkeer, Vishwanath Reddy, Bale M Swamy, Shashikala R Inamdar, Padma Shastry
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79311 (2013)
We have previously demonstrated immunostimulatory activity of a fungal lectin, Rhizoctonia bataticola lectin (RBL), towards normal human peripheral blood mononuclear cells. The present study aimed to explore the anticancer activities of RBL using hum
Externí odkaz:
https://doaj.org/article/f196ce7f1294467e80b23f44a0828f9b
Disruption of C1galt1 Gene Promotes Development and Metastasis of Pancreatic Adenocarcinomas in Mice
Autor:
Ramesh Pothuraju, Sidharth Mahapatra, Srikanth Barkeer, Lynette M. Smith, Moorthy P. Ponnusamy, Seema Chugh, Pranita Atri, Lijun Xia, Sriram Neelamegham, Rama Krishna Nimmakayala, Ishwor Thapa, Geoffrey A. Talmon, Surinder K. Batra, Satyanarayana Rachagani, Jianxin Fu, Naveenkumar Perumal, Xinheng Yu
Publikováno v:
Gastroenterology. 155:1608-1624
BACKGROUND & AIMS: Pancreatic ductal adenocarcinomas (PDACs) produce higher levels of truncated O-glycan structures (such as Tn and sTn) than normal pancreata. Dysregulated activity of core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a39a46d8aa604e7bc3f0eb125bec2ca9
https://doi.org/10.1053/j.gastro.2018.08.007
https://doi.org/10.1053/j.gastro.2018.08.007
Publikováno v:
Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 20, Iss 8, Pp 813-825 (2018)
Neoplasia: An International Journal for Oncology Research, Vol 20, Iss 8, Pp 813-825 (2018)
Aberrant glycosylation plays a critical role in tumor aggressiveness, progression, and metastasis. Emerging evidence associates cancer initiation and metastasis to the enrichment of cancer stem cells (CSCs). Several universal markers have been identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cddda5b0ef9da904ed9a0c2f0c47b88
https://doi.org/10.1016/j.neo.2018.06.001
https://doi.org/10.1016/j.neo.2018.06.001
Publikováno v:
Nutrition and Cancer: an international journal
TF antigen binding lectins from dietary sources PNA, ACA, ABL, JAC, and SRL from Sclerotium rolfsii have been reported to induce diverse effects on cancer cell proliferation by different mechanisms. This study aimed to compare effects of these lectin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b6b7ac227abefad84037dccebbfec71
https://pubmed.ncbi.nlm.nih.gov/30672325
https://pubmed.ncbi.nlm.nih.gov/30672325
Autor:
Ramakanth Chirravuri Venkata, Sanchita Rauth, Rama Krishna Nimmakayala, Rohitesh Gupta, Saswati Karmakar, Palanisamy Nallasamy, Naveenkumar Perumal, Satyanarayana Rachagani, Venu Raman, Surinder K. Batra, Srikanth Barkeer, Frank Leon, Moorthy P. Ponnusamy
Publikováno v:
Gastroenterology
Background & Aims It is not clear how pancreatic cancer stem cells (CSCs) are regulated, resulting in ineffective treatments for pancreatic cancer. PAF1, a RNA polymerase II-associated factor 1 complex (PAF1C) component, maintains pluripotency of ste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fd93f5e8f7fdb9b2a6687986767fbfe
https://doi.org/10.1053/j.gastro.2020.07.053
https://doi.org/10.1053/j.gastro.2020.07.053
Autor:
Seema Chugh, Satyanarayana Rachagani, Saswati Karmakar, Moorthy P. Ponnusamy, Srikanth Barkeer, Sanchita Rauth, Surinder K. Batra, Garima Kaushik
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-15 (2018)
BMC Cancer
BMC Cancer
Background Glycosylation plays a critical role in the aggressiveness of pancreatic cancer (PC). Emerging evidences indicate significant involvement of cancer stem cells (CSCs) in PC aggressiveness. However, the importance of glycosylation in pancreat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb2b588c21ca41019882f4d323cd8d19
https://doi.org/10.1186/s12885-018-5074-2
https://doi.org/10.1186/s12885-018-5074-2
Autor:
Arunkumar Padmanaban, Deepak Saligrama Adavigowda, Shashikala R. Inamdar, Nilanjan Guha, Lu-Gang Yu, Bale M. Swamy, Vishwanathreddy Hothpet, Prajna Hegde, Srikanth Barkeer
Publikováno v:
Glycobiology. 25:1375-1391
Sclerotium rolfsii lectin (SRL) is a lectin isolated from fungus S. rolfsii and has high binding specificity toward the oncofetal Thomsen-Friedenreich carbohydrate antigen (Galβ1-3GalNAc-α-O-Ser/Thr, T or TF), which is expressed in more than 90% of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a8a042dd5ff9c954c71e3a3280df03f
https://doi.org/10.1093/glycob/cwv067
https://doi.org/10.1093/glycob/cwv067