Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Srikala, Raghavan"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Stem cells have been shown to play an important role in regenerative medicine due to their proliferative and differentiation potential. The challenge, however, lies in regulating and controlling their potential for this purpose. Stem cells are regula
Externí odkaz:
https://doaj.org/article/6a7c72131bbe40a0b8b40a342dbdbf87
Autor:
Oindrila Bhattacharjee, Uttkarsh Ayyangar, Ambika S. Kurbet, Vairavan Lakshmanan, Dasaradhi Palakodeti, Florent Ginhoux, Srikala Raghavan
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Macrophages are highly responsive to the environmental cues and are the primary responders to tissue stress and damage. While much is known about the role of macrophages during inflammatory disease progression; the initial series of events that set u
Externí odkaz:
https://doaj.org/article/9324be4d578f48be88a9de996f6dc2a6
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100729- (2021)
Summary: Generating high-quality electron microscopy images of the skin and keratinocytes can be challenging. Here we describe a simple protocol for scanning electron microscopy (SEM) of murine skin. The protocol enables characterization of the ultra
Externí odkaz:
https://doaj.org/article/1de6e880dc2141598c522b53d0aa166d
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
The extracellular matrix (ECM) is a complex network of proteins and proteoglycans secreted by keratinocytes, fibroblasts and immune cells. The function of the skin ECM has expanded from being a scaffold that provides structural integrity, to a more d
Externí odkaz:
https://doaj.org/article/ea967b4e9137404b951dae84a360f1e7
Autor:
Jingjing Wang, Yuheng Fu, Wenmao Huang, Ritusree Biswas, Avinanda Banerjee, Joshua A. Broussard, Zhihai Zhao, Dongmei Wang, Glen Bjerke, Srikala Raghavan, Jie Yan, Kathleen J. Green, Rui Yi
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Stiffness and actomyosin contractility are intrinsic mechanical properties of animal cells required for the shaping of tissues. However, whether tissue stem cells (SCs) and progenitors located within SC niche have different mechanical properties that
Autor:
Ambika S. Kurbet, Samarth Hegde, Oindrila Bhattacharjee, Srujan Marepally, Praveen K. Vemula, Srikala Raghavan
Publikováno v:
Cell Reports, Vol 16, Iss 12, Pp 3334-3347 (2016)
Epidermal knockout of integrin β1 results in complete disorganization of the basement membrane (BM), resulting in neonatal lethality. Here, we report that this disorganization is exacerbated by an early embryonic inflammatory response involving the
Externí odkaz:
https://doaj.org/article/5a0b2a2ae9254ea28a7a1c18c9d56330
Autor:
Uttkarsh Ayyangar, Aneesh Karkhanis, Heather Tay, Aliya Farissa Binte Afandi, Oindrila Bhattacharjee, Lee Sze Han, James Chan, Srikala Raghavan
Dysregulated macrophage responses and changes in tissue metabolism are hallmarks of chronic, sterile inflammation. However, the metabolic cues that direct and support macrophage functions are poorly understood. Here, we show that during sterile infla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78d7f0ff785719e021776084e02160e5
https://doi.org/10.1101/2022.07.29.501937
https://doi.org/10.1101/2022.07.29.501937
Publikováno v:
Cellular and molecular life sciences : CMLS. 78(6)
Transfer RNA (tRNA)-derived fragments (tRFs) are an emerging class of conserved small non-coding RNAs that play important roles in post-transcriptional gene regulation. High-throughput sequencing of multiple biological samples have identified heterog
Autor:
Valeri Vasioukhin, Manando Nakasaki, Graham D. Wright, Avinanda Banerjee, Ritusree Biswas, Srikala Raghavan, Vassily Kutyavin, Sergio Lembo, Colin Jamora, Vairavan Lakshmanan, Jie Yan, Zhihai Zhao, Robert S. Ross, Dasaradhi Palakodeti
Publikováno v:
SSRN Electronic Journal.
Vinculin, a mechanotransducer associated with both adherens junctions (AJ) and focal adhesions (FA) plays a central role in force transmission through these cell-cell and cell-substratum contacts. Here we describe the conditional knock out (KO) of vi