Exposure to Silver Nanospheres Leads to Altered Respiratory Mechanics and Delayed Immune Response in an in Vivo Murine Model

Autor: Danielle Botelho, Bey F. Leo, Christopher Massa, Srijata Sarkar, Terry Tetley, Kian F. Chung, Shu Chen, Mary P. Ryan, Alexandra Porter, Elena N. Atochina-Vasserman, Junfeng Zhang, Stephan Schwander, Andrew J. Gow

Publikováno v: Frontiers in Pharmacology, Vol 9 (2018)

Here we examine the organ level toxicology of both carbon black (CB) and silver nanoparticles (AgNP). We aim to determine metal-specific effects to respiratory function, inflammation and potential interactions with lung lining fluid (LLF). C57Bl6/J m

Externí odkaz: https://doaj.org/article/3f02a3b1d3824af78f4ea63ac2a45f7c

Modulation of Human Macrophage Responses to Mycobacterium tuberculosis by Silver Nanoparticles of Different Size and Surface Modification.

Autor: Srijata Sarkar, Bey Fen Leo, Claudia Carranza, Shu Chen, Cesar Rivas-Santiago, Alexandra E Porter, Mary P Ryan, Andrew Gow, Kian Fan Chung, Teresa D Tetley, Junfeng Jim Zhang, Panos G Georgopoulos, Pamela A Ohman-Strickland, Stephan Schwander

Publikováno v: PLoS ONE, Vol 10, Iss 11, p e0143077 (2015)

Exposure to silver nanoparticles (AgNP) used in consumer products carries potential health risks including increased susceptibility to infectious pathogens. Systematic assessments of antimicrobial macrophage immune responses in the context of AgNP ex

Externí odkaz: https://doaj.org/article/95dc6d0bf8704c56a3ff5ae7b7fc8a95

Variability in bioreactivity linked to changes in size and zeta potential of diesel exhaust particles in human immune cells.

Autor: Srijata Sarkar, Lin Zhang, Prasad Subramaniam, Ki-Bum Lee, Eric Garfunkel, Pamela A Ohman Strickland, Gediminas Mainelis, Paul J Lioy, Teresa D Tetley, Kian Fan Chung, Junfeng Zhang, Mary Ryan, Alex Porter, Stephan Schwander

Publikováno v: PLoS ONE, Vol 9, Iss 5, p e97304 (2014)

Acting as fuel combustion catalysts to increase fuel economy, cerium dioxide (ceria, CeO2) nanoparticles have been used in Europe as diesel fuel additives (Envirox™). We attempted to examine the effects of particles emitted from a diesel engine bur

Externí odkaz: https://doaj.org/article/747d89fb280843b0a3fb2e7e86caab08

Urban Air Pollution Particulates Suppress Human T-Cell Responses to Mycobacterium Tuberculosis

Autor: Hyejeong Choi, Raúl Quintana-Belmares, Srijata Sarkar, Stephan Schwander, Alvaro Osornio-Vargas, Olufunmilola Ibironke, Joyce Nwoko, Martha Torres, Claudia Carranza, Kathleen Black, Pamela Ohman-Strickland

Publikováno v: International Journal of Environmental Research and Public Health
Volume 16
Issue 21
International Journal of Environmental Research and Public Health, Vol 16, Iss 21, p 4112 (2019)

Tuberculosis (TB) and air pollution both contribute significantly to the global burden of disease. Epidemiological studies show that exposure to household and urban air pollution increase the risk of new infections with Mycobacterium tuberculosis (M.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::212571414dc3011071afcc1fcb3e1d80

Season and size of urban particulate matter differentially affect cytotoxicity and human immune responses to Mycobacterium tuberculosis

Autor: Stephan Schwander, Judith C. Chow, Srijata Sarkar, Martha Torres, Pamela Ohman-Strickland, Junfeng Zhang, John G. Watson, Qingyu Meng, Olufunmilola Ibironke, Alvaro Osornio-Vargas, Cesar Rivas-Santiago, Claudia Carranza

Publikováno v: PLoS ONE
PLoS ONE, Vol 14, Iss 7, p e0219122 (2019)

Exposure to air pollution particulate matter (PM) and tuberculosis (TB) are two of the leading global public health challenges affecting low and middle income countries. An estimated 4.26 million premature deaths are attributable to household air pol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28e2aa7b6a10e4c2ed7b6e098abcd5a0
https://pubmed.ncbi.nlm.nih.gov/31295271