Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Srigiridhar, Kotamraju"'
Supplementary Figures 1-3 from Statin-Induced Breast Cancer Cell Death: Role of Inducible Nitric Oxide and Arginase-Dependent Pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::075859163b26ce23694e2b5265833b04
https://doi.org/10.1158/0008-5472.22367619
https://doi.org/10.1158/0008-5472.22367619
Statins are widely used cholesterol-lowering drugs that selectively inhibit the enzyme 3-hydroxy-3-methylglutaryl CoA reductase, leading to decreased cholesterol biosynthesis. Emerging data indicate that statins stimulate apoptotic cell death in seve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8108a16bd933d39d19f92a49616b3588
https://doi.org/10.1158/0008-5472.c.6495624
https://doi.org/10.1158/0008-5472.c.6495624
Supplementary Legends 1-3 from Statin-Induced Breast Cancer Cell Death: Role of Inducible Nitric Oxide and Arginase-Dependent Pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25dc910fe3556e8e26b7eff8bfffe93e
https://doi.org/10.1158/0008-5472.22367616
https://doi.org/10.1158/0008-5472.22367616
Autor:
null Praveen Kumar Neeli, null Shashikanta Sahoo, null Santosh Karnewar, null Gajalakshmi Singuru, null Sriravali Pulipaka, null Sandhya Annamaneni, null Srigiridhar Kotamraju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d65f1e7cf918cf8ad7de04e828cbdd3
https://doi.org/10.1111/febs.16605/v2/response1
https://doi.org/10.1111/febs.16605/v2/response1
Autor:
Praveen Kumar Neeli, Shashikanta Sahoo, Santosh Karnewar, Gajalakshmi Singuru, Sriravali Pulipaka, Sandhya Annamaneni, Srigiridhar Kotamraju
Publikováno v:
The FEBS journalReferences.
DOT1L, a specific H3K79 methyltransferase, has a tumour-promoting role in various cancers, including triple-negative breast cancer (TNBC). However, the molecular mechanism by which the deregulated DOT1L promotes cancer progression is unclear. Herein,
Autor:
Sreevidya Mallappa, Shivakrishna Kallepu, Narendra Kumar Nagendla, Prathama S. Mainkar, Srigiridhar Kotamraju, Praveen Kumar Neeli, Mohana Krishna Reddy Mudiam, Srivari Chandrasekhar
Publikováno v:
ChemMedChem. 15:1826-1833
Late-stage functionalization (LSF) aids drug discovery efforts by introducing functional groups onto C-H bonds on pre-existing skeletons. We adopted the LSF strategy to synthesize analogues of the abundantly available triterpenoid, glycyrrhetinic aci
Autor:
Gajalakshmi Singuru, Sridhar Reddy Maddi, Praveen Kumar Neeli, Sravya Panangipalli, Rajkumar Banerjee, Surendar Reddy Bathula, Srigiridhar Kotamraju, Rajamannar Thennati, Altab Shaikh
Publikováno v:
Chemical communications (Cambridge, England). 57(92)
Herein, we document a self-assembling octyl-TPP tagged esculetin (Mito-Esc) as functionally active and as a novel small molecule siRNA delivery vector. While Mito-Esc itself induces selective breast cancer cell death, the amphiphilic nature of Mito-E
Autor:
Srigiridhar Kotamraju, Sudhakar Godeshala, Samaresh Sau, Anantha K Kanugula, Rajkumar Banerjee, Subrata Pore, Anirban Ganguly, Ramesh Ummanni
Publikováno v:
Journal of Cellular Biochemistry. 121:804-815
Anticancer drugs exert their effects on cancer cells by deregulating many pathways linked to cell cycle, apoptosis, etc. but cancer cells gradually become resistive against anticancer drugs, thereby necessitating the development of newer generation a
Autor:
Saikiran Reddy Peddi, Santosh Karnewar, Rajeswar Rao Vedula, Krishnaiah Vaarla, Srigiridhar Kotamraju, Devayani Panuganti, Vijjulatha Manga
Publikováno v:
ChemistrySelect. 4:4324-4330
Autor:
Anantha Koteswararao Kanugula, Vishnu M Dhople, Uwe Völker, Ramesh Ummanni, Srigiridhar Kotamraju
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108890 (2014)
Statins are increasingly being recognized as anti-cancer agents against various cancers including breast cancer. To understand the molecular pathways targeted by fluvastatin and its differential sensitivity against metastatic breast cancer cells, we
Externí odkaz:
https://doaj.org/article/0f89c344aeaf4797b2ac9df522707b7a