Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sridhar T. Narla"'
Publikováno v:
Pediatric Nephrology. 37:1721-1731
Urothelium is a specialized multilayer epithelium that lines the urinary tract from the proximal urethra to the kidney. In addition to proliferation and differentiation during development, urothelial injury postnatally triggers a robust regenerative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdb76ded99d42ee319d672e2a5495e37
https://doi.org/10.1007/s00467-021-05239-w
https://doi.org/10.1007/s00467-021-05239-w
Publikováno v:
Am J Pathol
Keratinocyte growth factor (KGF) improves cyclophosphamide-induced bladder injury. To understand the mechanisms, we subcutaneously administered KGF to mice 24 hours before i.p. cyclophosphamide administration, followed by histologic assays and immuno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7d898be34b757c510c40935a9ce457e
https://doi.org/10.1016/j.ajpath.2019.09.015
https://doi.org/10.1016/j.ajpath.2019.09.015
Publikováno v:
Am J Pathol
Keratinocyte growth factor (KGF) drives phosphorylated (activated) AKT (pAKT) in bladder urothelium, which correlates with cytoprotection from cyclophosphamide. The current study determined whether: i) KGF modifies AKT targets [B-cell lymphoma protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d3a54bd53c69645adce61b84a0514fe
https://pubmed.ncbi.nlm.nih.gov/35063403
https://pubmed.ncbi.nlm.nih.gov/35063403
Autor:
Christopher Terranova, Sridhar T Narla, Yu-Wei Lee, Jonathan Bard, Abhirath Parikh, Ewa K Stachowiak, Emmanuel S Tzanakakis, Michael J Buck, Barbara Birkaya, Michal K Stachowiak
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123380 (2015)
Genetic studies have placed the Fgfr1 gene at the top of major ontogenic pathways that enable gastrulation, tissue development and organogenesis. Using genome-wide sequencing and loss and gain of function experiments the present investigation reveals
Externí odkaz:
https://doaj.org/article/193ed05d732c4c73997f3b671222fe01
Publikováno v:
Pediatric nephrology (Berlin, Germany). 37(8)
Urothelium is a specialized multilayer epithelium that lines the urinary tract from the proximal urethra to the kidney. In addition to proliferation and differentiation during development, urothelial injury postnatally triggers a robust regenerative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3789b25c1f78c29d9717606a12fda562
https://pubmed.ncbi.nlm.nih.gov/34471946
https://pubmed.ncbi.nlm.nih.gov/34471946
Autor:
Sridhar T. Narla, Mehdi Nouraie, Daniel Bushnell, Timothy W. Hand, Justin T. Tometich, Carlton M. Bates, Caitlin Schaefer
Publikováno v:
Am J Pathol
Cyclophosphamide may cause hemorrhagic cystitis and eventually bladder urothelial cancer. Genetic determinants for poor outcomes are unknown. We assessed actions of fibroblast growth factor receptor (FGFR) 2 in urothelium after cyclophosphamide expos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5fc602ab6117d01aeb7bde50f170dc8
https://pubmed.ncbi.nlm.nih.gov/33385344
https://pubmed.ncbi.nlm.nih.gov/33385344
Autor:
K. Harikrishnan, D. Freedman, C. A. Benson, Siddhartha Dhiman, Ewa K. Stachowiak, Kristen J. Brennand, L. E. Bayona Chuye, Pinaki Sarder, Sridhar T. Narla, Michal K. Stachowiak, A. Dimitri, S. Elahi
Publikováno v:
Translational Psychiatry, Vol 7, Iss 11, Pp 1-24 (2017)
Translational Psychiatry
Translational Psychiatry
Studies of induced pluripotent stem cells (iPSCs) from schizophrenia patients and control individuals revealed that the disorder is programmed at the preneuronal stage, involves a common dysregulated mRNA transcriptome, and identified Integrative Nuc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e06b02bff9cc131ec772ff7223c5a226
http://link.springer.com/article/10.1038/s41398-017-0054-x
http://link.springer.com/article/10.1038/s41398-017-0054-x
Induced Pluripotent Stem Cells Reveal Common Neurodevelopmental Genome Deprograming in Schizophrenia
Publikováno v:
Results and problems in cell differentiation. 66
Schizophrenia is a neurodevelopmental disorder characterized by complex aberrations in the structure, wiring, and chemistry of multiple neuronal systems. The abnormal developmental trajectory of the brain is established during gestation, long before
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::07c281837508da3b665b341abb7ce172
https://pubmed.ncbi.nlm.nih.gov/30209658
https://pubmed.ncbi.nlm.nih.gov/30209658
Induced Pluripotent Stem Cells Reveal Common Neurodevelopmental Genome Deprograming in Schizophrenia
Publikováno v:
Results and Problems in Cell Differentiation ISBN: 9783319934846
Schizophrenia is a neurodevelopmental disorder characterized by complex aberrations in the structure, wiring, and chemistry of multiple neuronal systems. The abnormal developmental trajectory of the brain is established during gestation, long before
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::171056982b915296bd4a77ba3c4cda2e
https://doi.org/10.1007/978-3-319-93485-3_6
https://doi.org/10.1007/978-3-319-93485-3_6
Autor:
Ewa K. Stachowiak, Sridhar T. Narla, John M. Aletta, Brandon Decker, Michal K. Stachowiak, Courtney A. Benson, Barbara Birkaya
Publikováno v:
Journal of Cellular Physiology. 230:989-1002
In this review we summarize the current understanding of a novel integrative function of Fibroblast Growth Factor Receptor-1 (FGFR1) and its partner CREB Binding Protein (CBP) acting as a nuclear regulatory complex. Nuclear FGFR1 and CBP interact wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96ca1cc37f0a20529c4f27553c44bc0b
https://doi.org/10.1002/jcp.24879
https://doi.org/10.1002/jcp.24879