Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Sridhar Murahari"'
Autor:
William C. Kisseberth, Kenji Hosoya, Guillermo Couto, Ana Lara-Garcia, Carrie E. Kosarek, M. Guillaume Wientjes, Francisco J. Alvarez, Jason I. Couto, Jessie L.-S. Au, Sridhar Murahari
Publikováno v:
Journal of the American Animal Hospital Association. 50:12-18
Although conventional treatment of dogs with osteosarcoma (OSA) by amputation and chemotherapy results in reported survival times (STs) of 262–413 days, no major improvements in STs have occurred in the past 2 decades. Suramin is a polysulfonated n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86c90e320a4c26da55c0d34a551b396d
https://doi.org/10.5326/jaaha-ms-5958
https://doi.org/10.5326/jaaha-ms-5958
Autor:
William C. Kisseberth, Joao Felipe de Brito Galvao, Saikaew Sutayatram, Nongnuch Inpanbutr, Sridhar Murahari, Dennis J. Chew
Publikováno v:
American Journal of Veterinary Research. 73:1262-1272
Objective—To evaluate in vitro effects of gemcitabine alone and in combination with carboplatin on canine transitional cell carcinoma (TCC) cell lines. Sample—In vitro cultures of 5 canine TCC cell lines. Procedures—Cells were treated with gemc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae3b87af919737038850b9298669f46a
https://doi.org/10.2460/ajvr.73.8.1262
https://doi.org/10.2460/ajvr.73.8.1262
Autor:
Jillian L. Werbeck, Sherry T. Shu, Adrie van Bokhoven, Murali V.P. Nadella, Evan T. Keller, Nanda K. Thudi, Jessica K. Simmons, Ching-Shih Chen, Christina L. Williams, Laurie K. McCauley, William C. Kisseberth, Lisa G. Lanigan, Matthew Breen, Sridhar Murahari, Thomas J. Rosol, Chelsea K. Martin
Publikováno v:
The Prostate. 71:1251-1263
BACKGROUND. Prostate cancer in men has a high mortality and morbidity due to metastatic disease. The pathobiology of prostate cancer metastasis is not well understood and cell lines and animal models that recapitulate the complex nature of the diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::714b4ae7ade5c3b66a559d032e0c07a6
https://doi.org/10.1002/pros.21341
https://doi.org/10.1002/pros.21341
Autor:
Laurie K. McCauley, Joseph J. Pinzone, Chelsea K. Martin, Nanda K. Thudi, Jillian L. Werbeck, Lisa G. Lanigan, Evan T. Keller, Sridhar Murahari, Thomas J. Rosol, Sherry T. Shu
Publikováno v:
The Prostate. 71:615-625
BACKGROUND. Osteoblastic bone metastasis is the predominant phenotype observed in prostatecancerpatientsandisassociatedwithhighpatientmortalityandmorbidity.However,the mechanisms determining the development of this phenotype are not well understood.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b29d0fc7ff81521c7b5b5eeb1bfe8bec
https://doi.org/10.1002/pros.21277
https://doi.org/10.1002/pros.21277
Autor:
Dasheng Wang, Joelle M. Fenger, Samuel K. Kulp, William C. Kisseberth, Tzu-yin Lin, Ching-Shih Chen, Cheryl A. London, Misty D. Bear, Sridhar Murahari
Publikováno v:
Blood. 115:4217-4225
Histone hypoacetylation occurs in many cancers and inhibition of histone deacetylation is a promising approach to modulate these epigenetic changes. Our laboratory previously demonstrated that the histone deacetylase inhibitors (HDACis) vorinostat an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd2274bcc38cd17fdb765f551b4a6fbf
https://doi.org/10.1182/blood-2009-07-231985
https://doi.org/10.1182/blood-2009-07-231985
Publikováno v:
American Journal of Veterinary Research. 69:938-945
Objective—To determine whether exposure of canine cancer cells to histone deacetylase (HDAC) inhibitors S(+)-N-hydroxy-4-(3-methyl-2-phenyl-butyrylamino)benzamide (OSU-HDAC42) or suberoylanilide hydroxamic acid (SAHA) results in increased histone a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c641e5180a8bb7d69432f8faecd763d
https://doi.org/10.2460/ajvr.69.7.938
https://doi.org/10.2460/ajvr.69.7.938
Autor:
William C. Kisseberth, Kenji Hosoya, Cheryl A. London, C. Guillermo Couto, Albert Laio, Sridhar Murahari
Publikováno v:
American Journal of Veterinary Research. 69:519-526
Objective—To evaluate the biological activity of dihydroartemisinin on canine osteosarcoma cell lines in vitro. Sample Population—4 canine osteosarcoma cell lines. Procedures—Cell viability assays were performed on canine osteosarcoma cell line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e164c2eb42ef4b5f78f6a5f68c217224
https://doi.org/10.2460/ajvr.69.4.519
https://doi.org/10.2460/ajvr.69.4.519
Autor:
Mary Jo Burkhard, William C. Kisseberth, Shannon E. Duke, William Vernau, Murali V.P. Nadella, Carrie E. Kosarek, Matthew Breen, Thomas J. Rosol, Sridhar Murahari, Rachael Thomas, Anne C. Avery
Publikováno v:
Leukemia Research. 31:1709-1720
A novel canine lymphoma cell line, OSW, was established from the malignant pleural effusion of a dog with peripheral T-cell lymphoma. The immunoprofile as determined by flow cytometry was as follows: positive for CD45, CD49d, CD18, CD11a; weakly posi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e0c031fdd3fb1468aad8449ea20faa5
https://doi.org/10.1016/j.leukres.2007.04.003
https://doi.org/10.1016/j.leukres.2007.04.003
Autor:
Nanda K, Thudi, Sherry T, Shu, Chelsea K, Martin, Lisa G, Lanigan, Murali V P, Nadella, Adrie, Van Bokhoven, Jillian L, Werbeck, Jessica K, Simmons, Sridhar, Murahari, William C, Kisseberth, Matthew, Breen, Christina, Williams, Ching-Shih, Chen, Laurie K, McCauley, Evan T, Keller, Thomas J, Rosol
Publikováno v:
The Prostate. 71(12)
Prostate cancer in men has a high mortality and morbidity due to metastatic disease. The pathobiology of prostate cancer metastasis is not well understood and cell lines and animal models that recapitulate the complex nature of the disease are needed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5e39808bba941297eef44fcf3faea270
https://pubmed.ncbi.nlm.nih.gov/21321976
https://pubmed.ncbi.nlm.nih.gov/21321976
Autor:
Thomas J. Rosol, William C. Kisseberth, Ching-Shih Chen, Samuel K. Kulp, Francisco J. Alvarez, C. G. Couto, Sridhar Murahari
Publikováno v:
Veterinary and comparative oncology. 5(1)
Deregulation of the 3-phosphoinositide-dependent protein kinase-1 (PDK-1)/Akt signalling pathway is associated with prostate cancer development and progression. Inhibition of PDK-1/Akt signalling can be achieved using structurally optimized celecoxib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43e3ce33864b55b0f28ee1b2e75c1915
https://pubmed.ncbi.nlm.nih.gov/19754801
https://pubmed.ncbi.nlm.nih.gov/19754801