Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Sridhar K. Rabindran"'
Autor:
Rakesh Kumar, Sridhar K. Rabindran, Stanley D. Chamberlain, Joseph W. Wilson, J. Brad Shotwell, Russell R. Lapierre, Sapna Suravajjala, Kenneth R. Maksimchuk, Richard R. Gontarek, Ryan G. Kruger, Kelly Anderson, Jingsong Yang, Melissa Dumble, Charity Atkins, Dominic Leperi, Qi Liu, Arthur Groy, Jason L. Rowand, Susan Korenchuk, Peter Sabbatini
Supplementary Figure 8. Effect of GSK1838705A on ALK signaling in vitro.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c8f9f20d530fd4470a9849f97c07aa3
https://doi.org/10.1158/1535-7163.22485563.v1
https://doi.org/10.1158/1535-7163.22485563.v1
Autor:
Rakesh Kumar, Sridhar K. Rabindran, Stanley D. Chamberlain, Joseph W. Wilson, J. Brad Shotwell, Russell R. Lapierre, Sapna Suravajjala, Kenneth R. Maksimchuk, Richard R. Gontarek, Ryan G. Kruger, Kelly Anderson, Jingsong Yang, Melissa Dumble, Charity Atkins, Dominic Leperi, Qi Liu, Arthur Groy, Jason L. Rowand, Susan Korenchuk, Peter Sabbatini
Supplementary Table 1. Kinase selectivity data for GSK1838705A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7533d44c0071694a414cc14a810679f4
https://doi.org/10.1158/1535-7163.22485560
https://doi.org/10.1158/1535-7163.22485560
Autor:
Rakesh Kumar, Sridhar K. Rabindran, Stanley D. Chamberlain, Joseph W. Wilson, J. Brad Shotwell, Russell R. Lapierre, Sapna Suravajjala, Kenneth R. Maksimchuk, Richard R. Gontarek, Ryan G. Kruger, Kelly Anderson, Jingsong Yang, Melissa Dumble, Charity Atkins, Dominic Leperi, Qi Liu, Arthur Groy, Jason L. Rowand, Susan Korenchuk, Peter Sabbatini
Supplementary Figure 2. Representative cell cycle histograms from MCF-7 and NCIH929 cells treated with 1 μM of GSK1838705A for 48 h.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71a34a7fd7357d1bf97276dd3cb1c267
https://doi.org/10.1158/1535-7163.22485581.v1
https://doi.org/10.1158/1535-7163.22485581.v1
Autor:
Rakesh Kumar, Sridhar K. Rabindran, Stanley D. Chamberlain, Joseph W. Wilson, J. Brad Shotwell, Russell R. Lapierre, Sapna Suravajjala, Kenneth R. Maksimchuk, Richard R. Gontarek, Ryan G. Kruger, Kelly Anderson, Jingsong Yang, Melissa Dumble, Charity Atkins, Dominic Leperi, Qi Liu, Arthur Groy, Jason L. Rowand, Susan Korenchuk, Peter Sabbatini
Supplementary Figure 1. Cell cycle effects of GSK1838705A.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35dbf19db7624f81e1b1bd2711932df6
https://doi.org/10.1158/1535-7163.22485584
https://doi.org/10.1158/1535-7163.22485584
Autor:
Rakesh Kumar, Sridhar K. Rabindran, Kyle A. Emmitte, Brian J. Wilson, Kelly Anderson, Jingsong Yang, Melissa Dumble, Charity Atkins, Qi Liu, Susan Korenchuk, Arthur Groy, Jason L. Rowand, Peter Sabbatini
Supplementary Data from Antitumor Activity of GSK1904529A, a Small-molecule Inhibitor of the Insulin-like Growth Factor-I Receptor Tyrosine Kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17ee3dbcdc2cbf5caa4c1c56dba5fcb3
https://doi.org/10.1158/1078-0432.22440624
https://doi.org/10.1158/1078-0432.22440624
Autor:
Rakesh Kumar, Sridhar K. Rabindran, Stanley D. Chamberlain, Joseph W. Wilson, J. Brad Shotwell, Russell R. Lapierre, Sapna Suravajjala, Kenneth R. Maksimchuk, Richard R. Gontarek, Ryan G. Kruger, Kelly Anderson, Jingsong Yang, Melissa Dumble, Charity Atkins, Dominic Leperi, Qi Liu, Arthur Groy, Jason L. Rowand, Susan Korenchuk, Peter Sabbatini
Supplementary Figure 6. Glucose metabolism after 8-day treatment of GSK1838705A.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89ae9917b8bd7e74ea01fd3a9c74c704
https://doi.org/10.1158/1535-7163.22485569
https://doi.org/10.1158/1535-7163.22485569
Autor:
Rakesh Kumar, Sridhar K. Rabindran, Stanley D. Chamberlain, Joseph W. Wilson, J. Brad Shotwell, Russell R. Lapierre, Sapna Suravajjala, Kenneth R. Maksimchuk, Richard R. Gontarek, Ryan G. Kruger, Kelly Anderson, Jingsong Yang, Melissa Dumble, Charity Atkins, Dominic Leperi, Qi Liu, Arthur Groy, Jason L. Rowand, Susan Korenchuk, Peter Sabbatini
Supplementary Figure 5. Anti-tumor activity of GSK1838705A in additional xenografts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::042e952df16d3281d40085d1dcc1e123
https://doi.org/10.1158/1535-7163.22485572
https://doi.org/10.1158/1535-7163.22485572
Autor:
Rakesh Kumar, Sridhar K. Rabindran, Stanley D. Chamberlain, Joseph W. Wilson, J. Brad Shotwell, Russell R. Lapierre, Sapna Suravajjala, Kenneth R. Maksimchuk, Richard R. Gontarek, Ryan G. Kruger, Kelly Anderson, Jingsong Yang, Melissa Dumble, Charity Atkins, Dominic Leperi, Qi Liu, Arthur Groy, Jason L. Rowand, Susan Korenchuk, Peter Sabbatini
Supplementary Figure 4. Effects of GSK1838705A on animal weights.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7af1c66109d25b6a310b2677f52b0c01
https://doi.org/10.1158/1535-7163.22485575
https://doi.org/10.1158/1535-7163.22485575
Autor:
Rakesh Kumar, Sridhar K. Rabindran, Stanley D. Chamberlain, Joseph W. Wilson, J. Brad Shotwell, Russell R. Lapierre, Sapna Suravajjala, Kenneth R. Maksimchuk, Richard R. Gontarek, Ryan G. Kruger, Kelly Anderson, Jingsong Yang, Melissa Dumble, Charity Atkins, Dominic Leperi, Qi Liu, Arthur Groy, Jason L. Rowand, Susan Korenchuk, Peter Sabbatini
The insulin-like growth factor-I receptor (IGF-IR) signaling pathway is activated in various tumors, and inhibition of IGF-IR kinase provides a therapeutic opportunity in these patients. GSK1838705A is a small-molecule kinase inhibitor that inhibits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a23acaf05c0a5f96e6ac563a34f9564
https://doi.org/10.1158/1535-7163.c.6532001
https://doi.org/10.1158/1535-7163.c.6532001
Autor:
Rakesh Kumar, Sridhar K. Rabindran, Stanley D. Chamberlain, Joseph W. Wilson, J. Brad Shotwell, Russell R. Lapierre, Sapna Suravajjala, Kenneth R. Maksimchuk, Richard R. Gontarek, Ryan G. Kruger, Kelly Anderson, Jingsong Yang, Melissa Dumble, Charity Atkins, Dominic Leperi, Qi Liu, Arthur Groy, Jason L. Rowand, Susan Korenchuk, Peter Sabbatini
Supplementary Figure 3. A. Time course of IGF-1R inhibition in vivo. B. Effect of GSK1838705A on IGF-1R signaling in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2da4c5bfbaad320a1cf0248ce348a22c
https://doi.org/10.1158/1535-7163.22485578
https://doi.org/10.1158/1535-7163.22485578