Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Sridevi Nagaraja"'
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
A deep neural network-based artificial intelligence (AI) model was assessed for its utility in predicting vital signs of hemorrhage patients and optimizing the management of fluid resuscitation in mass casualties. With the use of a cardio-respiratory
Externí odkaz:
https://doaj.org/article/4f5d43bb9fe94465b6c616d561332180
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Hyperalgesic priming, a form of neuroplasticity induced by inflammatory mediators, in peripheral nociceptors enhances the magnitude and duration of action potential (AP) firing to future inflammatory events and can potentially lead to pain chronifica
Externí odkaz:
https://doaj.org/article/79aeca94a1334874a6dc8bfce52d777d
Publikováno v:
Clean Energy; Oct2024, Vol. 8 Issue 5, p218-228, 11p
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Sensory neurons embedded in muscle tissue that initiate pain sensations, i.e., nociceptors, are temporarily sensitized by inflammatory mediators during musculoskeletal trauma. These neurons transduce peripheral noxious stimuli into an electrical sign
Externí odkaz:
https://doaj.org/article/941864d804ff4b73a98d991909b3d082
Autor:
Sridevi Nagaraja, Luis F. Queme, Megan C. Hofmann, Shivendra G. Tewari, Michael P. Jankowski, Jaques Reifman
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Nociceptive nerve endings embedded in muscle tissue transduce peripheral noxious stimuli into an electrical signal [i.e., an action potential (AP)] to initiate pain sensations. A major contributor to nociception from the muscles is mechanosensation.
Externí odkaz:
https://doaj.org/article/a14c0fada30744a68434c06eb308f1cc
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-13 (2018)
Abstract Background Pathological scarring in wounds is a prevalent clinical outcome with limited prognostic options. The objective of this study was to investigate whether cellular signaling proteins could be used as prognostic biomarkers of patholog
Externí odkaz:
https://doaj.org/article/fe4e82ee0c04494194403e53adceecbe
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Impaired angiogenesis is a hallmark of wounds with delayed healing, and currently used therapies to restore angiogenesis have limited efficacy. Here, we employ a computational simulation-based approach to identify influential molecular and cellular p
Externí odkaz:
https://doaj.org/article/3ad8108a25004facae08cd0a35b3baef
Publikováno v:
International journal for numerical methods in biomedical engineeringREFERENCES.
Mathematical models of human cardiovascular and respiratory systems provide a viable alternative to generate synthetic data to train artificial intelligence (AI) clinical decision-support systems and assess closed-loop control technologies, for milit
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 12, p e1004460 (2015)
Timely resolution of inflammation is critical for the restoration of homeostasis in injured or infected tissue. Chronic inflammation is often characterized by a persistent increase in the concentrations of inflammatory cells and molecular mediators,
Externí odkaz:
https://doaj.org/article/c863b9249c5d40d8b2b511f3312272c6
Autor:
Yan Zhao, Sridevi Nagaraja, Alexander Y. Mitrophanov, Lin Chen, Luisa A. DiPietro, Jian Zhou, David Fine, Jaques Reifman
Publikováno v:
Wound Repair and Regeneration. 25:366-376
Mac-1 (CD11b/CD18) is a macrophage receptor that plays several critical roles in macrophage recruitment and activation. Because macrophages are essential for proper wound healing, the impact of Mac-1 deficiency on wound healing is of significant inte